Click here to switch to the map view.

The map label for this gene is argB [H]

Identifier: 45357626

GI number: 45357626

Start: 75475

End: 76359

Strand: Direct

Name: argB [H]

Synonym: MMP0063

Alternate gene names: 45357626

Gene position: 75475-76359 (Clockwise)

Preceding gene: 45357621

Following gene: 45357627

Centisome position: 4.54

GC content: 38.53

Gene sequence:

>885_bases
ATGGAAGACTACACAAAAGCAGAAATTTTAATCGAAGCCCTGCCTTACATCTGTAAATTTCACGATCAGAAGATTTTAAT
TAAGTACGGCGGCCACGCTATGGTAAACGAGCAGGCAAAGAACTGGATTGCAAAAGACCTCGTGCTTTTGAAATATGTTG
GCATAAACCCGATAGTAGTACACGGCGGCGGCCCTGAAATCAATCGTGCGATGGAAAAAATGGGAAAAACCCCTGAATTT
ATTCACGGGCTTCGTGTAACTGATGAAGAAACACTTGATATTGTTAAAATGGTTCTTATTGGTAAAATAAATGGTGACAT
TGTTTCAAAATTAGAACGATACGGCGGAAAATCTGTCGGTCTTTCTGGAAAATCAGGTCAATTAATTAAAGCAAAGAAAA
AAATCCAGTATTTAATGAAAGACAGCCAAAAAATCGAAGTAGATCTCGGAATGGTCGGAGAAGTCGAACATGTCGACACA
AAATTAATAGATATATTAGTTGAAAAACGCTACATTCCGGTAATTTCCCCAATAGGTGTTGACCACCAAGGAAATGATTT
AAACTTAAACGCAGACATTGCTGCTGGAGATATTGCAGGTGCAATGAACGCTCAAAAACTTATAATGGTCACAGACGTTG
ATGGAATAATGGACGACGTAAATGACCCATCTACCCTTCACAGGAGATTAACTATTCCTCAAATTGAAGATATGATCGAA
AAAGGGCTTATTACTGGTGGTATGATTCCAAAAATCGAAGCATGTGTCAATGCACTTGACAAAGGAGTTCAGAGTGTACA
CATAGTAAATGGAAAAACTCCTCACGCAGTTCTTCTTGAAATTTTCACGGAAGATGGTGTGGGTACCATGGTTGTAAGAG
AATAA

Upstream 100 bases:

>100_bases
TTCCATATTATGCACCTCCGCATGGATTAAAAAATGTATAAATATTAAATCATATAGAATATGAAAAAACAATATTTAAA
TATTTTGGTGAGCGGGTAAC

Downstream 100 bases:

>100_bases
CTTTCTTTTTTTAATTTTTCAAACTCTTTAAATTCTTCTTTTATCTGAAAAATATATCTATTTATTGGTCTATTTGGATT
AAAAAAGATTTAAATTTTTA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MEDYTKAEILIEALPYICKFHDQKILIKYGGHAMVNEQAKNWIAKDLVLLKYVGINPIVVHGGGPEINRAMEKMGKTPEF
IHGLRVTDEETLDIVKMVLIGKINGDIVSKLERYGGKSVGLSGKSGQLIKAKKKIQYLMKDSQKIEVDLGMVGEVEHVDT
KLIDILVEKRYIPVISPIGVDHQGNDLNLNADIAAGDIAGAMNAQKLIMVTDVDGIMDDVNDPSTLHRRLTIPQIEDMIE
KGLITGGMIPKIEACVNALDKGVQSVHIVNGKTPHAVLLEIFTEDGVGTMVVRE

Sequences:

>Translated_294_residues
MEDYTKAEILIEALPYICKFHDQKILIKYGGHAMVNEQAKNWIAKDLVLLKYVGINPIVVHGGGPEINRAMEKMGKTPEF
IHGLRVTDEETLDIVKMVLIGKINGDIVSKLERYGGKSVGLSGKSGQLIKAKKKIQYLMKDSQKIEVDLGMVGEVEHVDT
KLIDILVEKRYIPVISPIGVDHQGNDLNLNADIAAGDIAGAMNAQKLIMVTDVDGIMDDVNDPSTLHRRLTIPQIEDMIE
KGLITGGMIPKIEACVNALDKGVQSVHIVNGKTPHAVLLEIFTEDGVGTMVVRE
>Mature_294_residues
MEDYTKAEILIEALPYICKFHDQKILIKYGGHAMVNEQAKNWIAKDLVLLKYVGINPIVVHGGGPEINRAMEKMGKTPEF
IHGLRVTDEETLDIVKMVLIGKINGDIVSKLERYGGKSVGLSGKSGQLIKAKKKIQYLMKDSQKIEVDLGMVGEVEHVDT
KLIDILVEKRYIPVISPIGVDHQGNDLNLNADIAAGDIAGAMNAQKLIMVTDVDGIMDDVNDPSTLHRRLTIPQIEDMIE
KGLITGGMIPKIEACVNALDKGVQSVHIVNGKTPHAVLLEIFTEDGVGTMVVRE

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=288, Percent_Identity=28.4722222222222, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI145693208, Length=235, Percent_Identity=31.4893617021277, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320913, Length=291, Percent_Identity=27.8350515463918, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 32250; Mature: 32250

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDYTKAEILIEALPYICKFHDQKILIKYGGHAMVNEQAKNWIAKDLVLLKYVGINPIVV
CCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECHHHHHHHHHHHHHHHEECCCEEEE
HGGGPEINRAMEKMGKTPEFIHGLRVTDEETLDIVKMVLIGKINGDIVSKLERYGGKSVG
ECCCCHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEC
LSGKSGQLIKAKKKIQYLMKDSQKIEVDLGMVGEVEHVDTKLIDILVEKRYIPVISPIGV
CCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEECCCCC
DHQGNDLNLNADIAAGDIAGAMNAQKLIMVTDVDGIMDDVNDPSTLHRRLTIPQIEDMIE
CCCCCCEEEECCCCCCHHHCCCCCCEEEEEEECHHHHHCCCCHHHHHHCCCCHHHHHHHH
KGLITGGMIPKIEACVNALDKGVQSVHIVNGKTPHAVLLEIFTEDGVGTMVVRE
HCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MEDYTKAEILIEALPYICKFHDQKILIKYGGHAMVNEQAKNWIAKDLVLLKYVGINPIVV
CCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECHHHHHHHHHHHHHHHEECCCEEEE
HGGGPEINRAMEKMGKTPEFIHGLRVTDEETLDIVKMVLIGKINGDIVSKLERYGGKSVG
ECCCCHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEC
LSGKSGQLIKAKKKIQYLMKDSQKIEVDLGMVGEVEHVDTKLIDILVEKRYIPVISPIGV
CCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEECCCCC
DHQGNDLNLNADIAAGDIAGAMNAQKLIMVTDVDGIMDDVNDPSTLHRRLTIPQIEDMIE
CCCCCCEEEECCCCCCHHHCCCCCCEEEEEEECHHHHHCCCCHHHHHHCCCCHHHHHHHH
KGLITGGMIPKIEACVNALDKGVQSVHIVNGKTPHAVLLEIFTEDGVGTMVVRE
HCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA