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The map label for this gene is 45357607

Identifier: 45357607

GI number: 45357607

Start: 61568

End: 62914

Strand: Direct

Name: 45357607

Synonym: MMP0044

Alternate gene names: NA

Gene position: 61568-62914 (Clockwise)

Preceding gene: 45357606

Following gene: 45357608

Centisome position: 3.71

GC content: 37.27

Gene sequence:

>1347_bases
TTGCAGTTAGAAGTAGTCGCAATAGGTGGATACGAAGAAGTCGGAAGGAACATGACTGCCGTAAATATCGACGGCGAGAT
CATAATTTTCGATATGGGTGTAAGACTCGACAGGATAATGATTCACGAGGATACAGACATCTCAAAAATGCACAGTTTAA
ACTTGATTGAGATGGGCGTAATTCCAGATGATACGGTAATGAAAAATATCGAAGGAGAGGTTAAGGCGATTGTTTTAACG
CACGGGCACCTCGACCACATCGGAGCAATTACAAAACTTGCACACAGGTACAACGCTCCAATTATCGGAACTCCATACAC
TTTAGAACTCGTAAAAAGAGAAATTTTAAGCGAAAAGAAATTTGATGTTAGAAATCCATTAATTACTTTAGAAAACGGAA
ATAAATTAGATTTAACAGCAAATATTACTTTAGAATTTGTAAAAATTACACACAGTATTCCTGATGCTGCAATGGCAGTA
CTTCACACACCTTATGGTGCAGTAGTTTATGGAAACGACTTTAAATTTGATAATTTCCCTGTAGTTGGCGAAAAACCAGA
TTACAAAGCGTTAAAAAGAATTGGAAAACAGGGCGTAATTGCAATGGTTTCCGAAAGTACAAGAGTTGATTTTGAAGGAA
AAACAGCATCAGAAGGAGTTGCTGCAAACCTTTTGAAAAACGACCTTTTAGGAACTGACAACGAAGACAATGCGGTAGTA
GTAACTACATTTTCATCACACATTGCAAGAATTAAATCCATTACGGATATTGCTTCAAAAATGGGCAGAATTCCAGTACT
TGTTGGAAGATCCATGTCAAAATACTGTGGAATTGCACAAGATATCGGTTTAGTAAAATTCCCAAAAGAAACAAAAATTT
GCTGGGACCCTTCATCAATCGATAAAACCTTCCACCAGATAATGAAAGACGGTAAAGAAAACTACCTTATGGTTGTTACA
GGACACCAAGGAGAAGAAGGTGCGGTTTTATCCAGAATGGCAACAAATAAAACTCCATTTAGGTTTGAAAAATACGATCA
GGTTGTATTTTCAGCAGACGTTATTCCAAACCCAATGAATGCGGCACAAAGATATTTATTGGAAGCAAGATTAAATTTAG
CAGGAGTTAGGCTATTTAAAGGAGCTCACGTATCTGGACACGCGGCAAAAGAAGATCACAGGGACATATTAAGATGGTTA
CAACCCGAACACTTGATACCTGCTCACGGTGATTTTAATTTAACTTCAGCATATGCTAAATTAGCAGAAGAAGAAGGATT
CAGACTCGGTGAAGATGTACACTTACTCAGAAACGGTCAAAGCTTGAAATTTGAAAGAGTAATTTAA

Upstream 100 bases:

>100_bases
TTTAAAGAATTGGAAGGATCAGATTTAATAATTTAAATATTATCCATCGGAATTTTTTCAATTTATTTATTCATGTATTC
AAAGCAAAGGATGTGATAAT

Downstream 100 bases:

>100_bases
TTGAGGTGCTAAAATGGTGTTTGATAGGGAAATATTGTCAAAAATCGATTCTGAACTCAAAAAATACATGGAAAAAGATA
CTAAACTTTACGGTGCATCA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MQLEVVAIGGYEEVGRNMTAVNIDGEIIIFDMGVRLDRIMIHEDTDISKMHSLNLIEMGVIPDDTVMKNIEGEVKAIVLT
HGHLDHIGAITKLAHRYNAPIIGTPYTLELVKREILSEKKFDVRNPLITLENGNKLDLTANITLEFVKITHSIPDAAMAV
LHTPYGAVVYGNDFKFDNFPVVGEKPDYKALKRIGKQGVIAMVSESTRVDFEGKTASEGVAANLLKNDLLGTDNEDNAVV
VTTFSSHIARIKSITDIASKMGRIPVLVGRSMSKYCGIAQDIGLVKFPKETKICWDPSSIDKTFHQIMKDGKENYLMVVT
GHQGEEGAVLSRMATNKTPFRFEKYDQVVFSADVIPNPMNAAQRYLLEARLNLAGVRLFKGAHVSGHAAKEDHRDILRWL
QPEHLIPAHGDFNLTSAYAKLAEEEGFRLGEDVHLLRNGQSLKFERVI

Sequences:

>Translated_448_residues
MQLEVVAIGGYEEVGRNMTAVNIDGEIIIFDMGVRLDRIMIHEDTDISKMHSLNLIEMGVIPDDTVMKNIEGEVKAIVLT
HGHLDHIGAITKLAHRYNAPIIGTPYTLELVKREILSEKKFDVRNPLITLENGNKLDLTANITLEFVKITHSIPDAAMAV
LHTPYGAVVYGNDFKFDNFPVVGEKPDYKALKRIGKQGVIAMVSESTRVDFEGKTASEGVAANLLKNDLLGTDNEDNAVV
VTTFSSHIARIKSITDIASKMGRIPVLVGRSMSKYCGIAQDIGLVKFPKETKICWDPSSIDKTFHQIMKDGKENYLMVVT
GHQGEEGAVLSRMATNKTPFRFEKYDQVVFSADVIPNPMNAAQRYLLEARLNLAGVRLFKGAHVSGHAAKEDHRDILRWL
QPEHLIPAHGDFNLTSAYAKLAEEEGFRLGEDVHLLRNGQSLKFERVI
>Mature_448_residues
MQLEVVAIGGYEEVGRNMTAVNIDGEIIIFDMGVRLDRIMIHEDTDISKMHSLNLIEMGVIPDDTVMKNIEGEVKAIVLT
HGHLDHIGAITKLAHRYNAPIIGTPYTLELVKREILSEKKFDVRNPLITLENGNKLDLTANITLEFVKITHSIPDAAMAV
LHTPYGAVVYGNDFKFDNFPVVGEKPDYKALKRIGKQGVIAMVSESTRVDFEGKTASEGVAANLLKNDLLGTDNEDNAVV
VTTFSSHIARIKSITDIASKMGRIPVLVGRSMSKYCGIAQDIGLVKFPKETKICWDPSSIDKTFHQIMKDGKENYLMVVT
GHQGEEGAVLSRMATNKTPFRFEKYDQVVFSADVIPNPMNAAQRYLLEARLNLAGVRLFKGAHVSGHAAKEDHRDILRWL
QPEHLIPAHGDFNLTSAYAKLAEEEGFRLGEDVHLLRNGQSLKFERVI

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 49797; Mature: 49797

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLEVVAIGGYEEVGRNMTAVNIDGEIIIFDMGVRLDRIMIHEDTDISKMHSLNLIEMGV
CEEEEEEECCHHHHCCCEEEEEECCEEEEEECCCCEEEEEEECCCCHHHHHCCCEEEECC
IPDDTVMKNIEGEVKAIVLTHGHLDHIGAITKLAHRYNAPIIGTPYTLELVKREILSEKK
CCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
FDVRNPLITLENGNKLDLTANITLEFVKITHSIPDAAMAVLHTPYGAVVYGNDFKFDNFP
CCCCCCEEEECCCCEEEEEEEEEEEEEEEECCCCHHHHHHHCCCCCEEEECCCCCCCCCC
VVGEKPDYKALKRIGKQGVIAMVSESTRVDFEGKTASEGVAANLLKNDLLGTDNEDNAVV
CCCCCCCHHHHHHCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEE
VTTFSSHIARIKSITDIASKMGRIPVLVGRSMSKYCGIAQDIGLVKFPKETKICWDPSSI
EEEHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCHHHCCCEEECCCCCCEEECCHHH
DKTFHQIMKDGKENYLMVVTGHQGEEGAVLSRMATNKTPFRFEKYDQVVFSADVIPNPMN
HHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCCCEEHHHCEEEEECCCCCCCHH
AAQRYLLEARLNLAGVRLFKGAHVSGHAAKEDHRDILRWLQPEHLIPAHGDFNLTSAYAK
HHHHHHHHHHHCHHEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LAEEEGFRLGEDVHLLRNGQSLKFERVI
HHHHCCCCCCCCCCEEECCCCCEEEECC
>Mature Secondary Structure
MQLEVVAIGGYEEVGRNMTAVNIDGEIIIFDMGVRLDRIMIHEDTDISKMHSLNLIEMGV
CEEEEEEECCHHHHCCCEEEEEECCEEEEEECCCCEEEEEEECCCCHHHHHCCCEEEECC
IPDDTVMKNIEGEVKAIVLTHGHLDHIGAITKLAHRYNAPIIGTPYTLELVKREILSEKK
CCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
FDVRNPLITLENGNKLDLTANITLEFVKITHSIPDAAMAVLHTPYGAVVYGNDFKFDNFP
CCCCCCEEEECCCCEEEEEEEEEEEEEEEECCCCHHHHHHHCCCCCEEEECCCCCCCCCC
VVGEKPDYKALKRIGKQGVIAMVSESTRVDFEGKTASEGVAANLLKNDLLGTDNEDNAVV
CCCCCCCHHHHHHCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEE
VTTFSSHIARIKSITDIASKMGRIPVLVGRSMSKYCGIAQDIGLVKFPKETKICWDPSSI
EEEHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCHHHCCCEEECCCCCCEEECCHHH
DKTFHQIMKDGKENYLMVVTGHQGEEGAVLSRMATNKTPFRFEKYDQVVFSADVIPNPMN
HHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCCCEEHHHCEEEEECCCCCCCHH
AAQRYLLEARLNLAGVRLFKGAHVSGHAAKEDHRDILRWLQPEHLIPAHGDFNLTSAYAK
HHHHHHHHHHHCHHEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LAEEEGFRLGEDVHLLRNGQSLKFERVI
HHHHCCCCCCCCCCEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]