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The map label for this gene is yhdH [H]

Identifier: 42523422

GI number: 42523422

Start: 1857184

End: 1858551

Strand: Direct

Name: yhdH [H]

Synonym: Bd1945

Alternate gene names: 42523422

Gene position: 1857184-1858551 (Clockwise)

Preceding gene: 42523421

Following gene: 42523425

Centisome position: 49.09

GC content: 52.92

Gene sequence:

>1368_bases
ATGGCTAGTAAACGCGGCTCATGGAAAACACGCTATGGATTCTATCTTCTGGCCATCGGCTCTGCCTGTGGTTTGGGGAA
TCTGTGGCGTTTTCCCTATGTCGTGGGCGAAAATGGGGGCGGTGCCTTCATTTTGCTTTATGGTCTGCTGGCTTTGGCCA
TCGGCGCTCCGCTGTTGATTGCCGAGCTGATGCTGGGTAAAGGCACGCGCCGTTCGGTGATCGTCGCTACCCAGCAGATG
AGTGCCAAGACCGGCGTGAATTTCCGCTGGGTCGGGCGACTGGCCGTGATGGTCAGTATTGTCGTCTTGTCTTATTACTC
AGTGATCAGTGGCTGGGTTTTGCACTTCTTAACCCAATTCCTGGTGTCTTTATTTTCCAGCCCCGAACAACTGACTGACA
AAACCAATCTGGCAGCTTTGATGTCTAACGGCTGGCTGCAGTTGATGCTGGCCAGTGCGCACATCCTGATCACGGTGGTT
GTGGTCGTCAAAGGGGTGCAGCAGGGGTTGGAGCGCTGGATCGGGTACACCATGCCGTTATTTGCGGTGCTGGTTATTAT
TCTGGTCATGCGTTCTTTCTCGCTGCCTTCAACTCCGGAAGTGTTGCGCTTCCTGTTTTATCCGGACTTTTCAAAGCTGA
GCTGGGATTCCATCAATCACGCTCTGGGGCATGTGTTCTTCACGCTTTCAGTGGGCTTTGGCACGATGGTGACCTTTGGT
TCTTACATGCGTGAAGAAGACCACGTTCCGACCGCGGGTTTCCGTGTGACGATCGTGGATACAGTGATTTCCTTGGTGGC
CGTGGTGATGATTTTCCCGGTGGCGTTCCAGGCGTCCAATGTGCCGCTGACGGATCCGGCGTTGATGTTTGAGGTCTTGC
CGAAGTATCTGTTGGGAATCCGTGGGGGCACGCTGTTTGGTCTGGCGTTCTTTGCGTGTCTTTATATGGCAGCGCTGAAT
GCCAGCATTGGTTTGCTGGAAGTTGTCGTGTCCAATTGGGTGGATGCCAAGAAAGAAATGGAGCGTGGCAAGGCGACCTG
GTATTCCGGGGCGATTGCTTTGATGCTGACGGTTCTGCCGGCGCTTTCAAGTTCGATCTTTAAAGACATCCGCGTGGGTG
GCCGTTCGTTGATCGAAAATCTGGATTCATTGCTGATCAACTGGCTGCTGCCGTTGGTGGCGCTGGGTATTTTGATCGCC
TTCAATCGCGGGGTTTCAGACAAGGAAAAAGAGCTGGGCTTTGTCGACAAGGACAAGTTCGTCAGCTATTCAATGTATCC
GCATTGGATGTTTGTTTTGAAGTGGGCAGGCCCGGTGGTGATTATCGTGGGCCTTTTGCTGCAAGTTATTGGGGTTTTTG
TCAGTTAG

Upstream 100 bases:

>100_bases
TATCGCCGCTTCCTGATTAAGCACATTAAAACGAACTGGGACCTTCACGGGATGCCGATTCGTATCTTCTGTATGAAATC
ACGCCGTGGTGGATCGGATA

Downstream 100 bases:

>100_bases
ACGGGGATGATTAGAAGTTCATCCCCAGGATCACCAGGAAGTTATAGAAGTCACCGGTCAGATTCTTATCCAGCTTTTCA
GTTCCATCCACGTAGGACTT

Product: sodium-dependent serine transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MASKRGSWKTRYGFYLLAIGSACGLGNLWRFPYVVGENGGGAFILLYGLLALAIGAPLLIAELMLGKGTRRSVIVATQQM
SAKTGVNFRWVGRLAVMVSIVVLSYYSVISGWVLHFLTQFLVSLFSSPEQLTDKTNLAALMSNGWLQLMLASAHILITVV
VVVKGVQQGLERWIGYTMPLFAVLVIILVMRSFSLPSTPEVLRFLFYPDFSKLSWDSINHALGHVFFTLSVGFGTMVTFG
SYMREEDHVPTAGFRVTIVDTVISLVAVVMIFPVAFQASNVPLTDPALMFEVLPKYLLGIRGGTLFGLAFFACLYMAALN
ASIGLLEVVVSNWVDAKKEMERGKATWYSGAIALMLTVLPALSSSIFKDIRVGGRSLIENLDSLLINWLLPLVALGILIA
FNRGVSDKEKELGFVDKDKFVSYSMYPHWMFVLKWAGPVVIIVGLLLQVIGVFVS

Sequences:

>Translated_455_residues
MASKRGSWKTRYGFYLLAIGSACGLGNLWRFPYVVGENGGGAFILLYGLLALAIGAPLLIAELMLGKGTRRSVIVATQQM
SAKTGVNFRWVGRLAVMVSIVVLSYYSVISGWVLHFLTQFLVSLFSSPEQLTDKTNLAALMSNGWLQLMLASAHILITVV
VVVKGVQQGLERWIGYTMPLFAVLVIILVMRSFSLPSTPEVLRFLFYPDFSKLSWDSINHALGHVFFTLSVGFGTMVTFG
SYMREEDHVPTAGFRVTIVDTVISLVAVVMIFPVAFQASNVPLTDPALMFEVLPKYLLGIRGGTLFGLAFFACLYMAALN
ASIGLLEVVVSNWVDAKKEMERGKATWYSGAIALMLTVLPALSSSIFKDIRVGGRSLIENLDSLLINWLLPLVALGILIA
FNRGVSDKEKELGFVDKDKFVSYSMYPHWMFVLKWAGPVVIIVGLLLQVIGVFVS
>Mature_454_residues
ASKRGSWKTRYGFYLLAIGSACGLGNLWRFPYVVGENGGGAFILLYGLLALAIGAPLLIAELMLGKGTRRSVIVATQQMS
AKTGVNFRWVGRLAVMVSIVVLSYYSVISGWVLHFLTQFLVSLFSSPEQLTDKTNLAALMSNGWLQLMLASAHILITVVV
VVKGVQQGLERWIGYTMPLFAVLVIILVMRSFSLPSTPEVLRFLFYPDFSKLSWDSINHALGHVFFTLSVGFGTMVTFGS
YMREEDHVPTAGFRVTIVDTVISLVAVVMIFPVAFQASNVPLTDPALMFEVLPKYLLGIRGGTLFGLAFFACLYMAALNA
SIGLLEVVVSNWVDAKKEMERGKATWYSGAIALMLTVLPALSSSIFKDIRVGGRSLIENLDSLLINWLLPLVALGILIAF
NRGVSDKEKELGFVDKDKFVSYSMYPHWMFVLKWAGPVVIIVGLLLQVIGVFVS

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=396, Percent_Identity=26.5151515151515, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI289191351, Length=397, Percent_Identity=25.9445843828715, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4557046, Length=397, Percent_Identity=25.9445843828715, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI289191377, Length=397, Percent_Identity=25.9445843828715, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4507043, Length=393, Percent_Identity=26.7175572519084, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4507041, Length=396, Percent_Identity=26.7676767676768, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI33354281, Length=312, Percent_Identity=26.9230769230769, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI21361581, Length=388, Percent_Identity=23.1958762886598, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI194018524, Length=311, Percent_Identity=27.6527331189711, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI51468073, Length=310, Percent_Identity=28.0645161290323, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI58219014, Length=310, Percent_Identity=26.4516129032258, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI7657587, Length=387, Percent_Identity=24.031007751938, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI134304856, Length=412, Percent_Identity=26.4563106796117, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI171184408, Length=381, Percent_Identity=23.6220472440945, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI171184406, Length=381, Percent_Identity=23.6220472440945, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI171184404, Length=381, Percent_Identity=23.6220472440945, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI11181770, Length=313, Percent_Identity=25.5591054313099, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI197276623, Length=343, Percent_Identity=24.7813411078717, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI54607094, Length=343, Percent_Identity=24.7813411078717, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI21361693, Length=119, Percent_Identity=37.8151260504202, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI67782317, Length=394, Percent_Identity=23.3502538071066, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI67782313, Length=394, Percent_Identity=23.3502538071066, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI92859670, Length=142, Percent_Identity=32.3943661971831, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI67782315, Length=394, Percent_Identity=23.3502538071066, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI12408638, Length=289, Percent_Identity=24.9134948096886, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI5032097, Length=346, Percent_Identity=23.4104046242775, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI6005715, Length=115, Percent_Identity=35.6521739130435, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI197276625, Length=116, Percent_Identity=31.8965517241379, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI218563756, Length=340, Percent_Identity=23.5294117647059, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI289191353, Length=384, Percent_Identity=22.9166666666667, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=509, Percent_Identity=23.5756385068762, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71995588, Length=432, Percent_Identity=23.3796296296296, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25146584, Length=388, Percent_Identity=21.6494845360825, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17569475, Length=387, Percent_Identity=26.8733850129199, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17554804, Length=346, Percent_Identity=24.2774566473988, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17542050, Length=148, Percent_Identity=32.4324324324324, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17136952, Length=383, Percent_Identity=26.3707571801567, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281364394, Length=382, Percent_Identity=26.9633507853403, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28574704, Length=382, Percent_Identity=26.9633507853403, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI17136950, Length=382, Percent_Identity=26.9633507853403, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28574702, Length=382, Percent_Identity=26.9633507853403, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45550877, Length=452, Percent_Identity=26.5486725663717, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24762620, Length=375, Percent_Identity=25.3333333333333, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI45551183, Length=409, Percent_Identity=26.6503667481663, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24661428, Length=461, Percent_Identity=25.3796095444685, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24639514, Length=511, Percent_Identity=24.6575342465753, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI221329674, Length=511, Percent_Identity=24.6575342465753, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19921936, Length=378, Percent_Identity=25.6613756613757, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24639516, Length=531, Percent_Identity=23.728813559322, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24652942, Length=384, Percent_Identity=23.1770833333333, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45551088, Length=384, Percent_Identity=23.1770833333333, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24655079, Length=309, Percent_Identity=26.537216828479, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281363702, Length=300, Percent_Identity=27.3333333333333, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281363700, Length=300, Percent_Identity=26, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582567, Length=312, Percent_Identity=23.0769230769231, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654186, Length=117, Percent_Identity=35.8974358974359, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281365034, Length=387, Percent_Identity=22.9974160206718, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24639853, Length=307, Percent_Identity=22.4755700325733, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364136, Length=402, Percent_Identity=22.8855721393035, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49982; Mature: 49851

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKRGSWKTRYGFYLLAIGSACGLGNLWRFPYVVGENGGGAFILLYGLLALAIGAPLLI
CCCCCCCCCHHHCEEEEEECCCCCCCCHHHCCEEEECCCCCHHHHHHHHHHHHHCCHHHH
AELMLGKGTRRSVIVATQQMSAKTGVNFRWVGRLAVMVSIVVLSYYSVISGWVLHFLTQF
HHHHHCCCCCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVSLFSSPEQLTDKTNLAALMSNGWLQLMLASAHILITVVVVVKGVQQGLERWIGYTMPL
HHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
FAVLVIILVMRSFSLPSTPEVLRFLFYPDFSKLSWDSINHALGHVFFTLSVGFGTMVTFG
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SYMREEDHVPTAGFRVTIVDTVISLVAVVMIFPVAFQASNVPLTDPALMFEVLPKYLLGI
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
RGGTLFGLAFFACLYMAALNASIGLLEVVVSNWVDAKKEMERGKATWYSGAIALMLTVLP
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ALSSSIFKDIRVGGRSLIENLDSLLINWLLPLVALGILIAFNRGVSDKEKELGFVDKDKF
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHC
VSYSMYPHWMFVLKWAGPVVIIVGLLLQVIGVFVS
EEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASKRGSWKTRYGFYLLAIGSACGLGNLWRFPYVVGENGGGAFILLYGLLALAIGAPLLI
CCCCCCCCHHHCEEEEEECCCCCCCCHHHCCEEEECCCCCHHHHHHHHHHHHHCCHHHH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EEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]