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The map label for this gene is era [H]

Identifier: 42523420

GI number: 42523420

Start: 1854953

End: 1855864

Strand: Direct

Name: era [H]

Synonym: Bd1942

Alternate gene names: 42523420

Gene position: 1854953-1855864 (Clockwise)

Preceding gene: 42523419

Following gene: 42523421

Centisome position: 49.03

GC content: 49.45

Gene sequence:

>912_bases
ATGAGTTACAAAGCTGGATTTTTAGGTCTGATCGGACAGCCGAACGCGGGGAAGAGCACATTGATGAACTTCCTTGTGGA
CGAAAAGGTCTCTATCGTCTCTTCAAAACCTCAGACAACCCGCCGCCGCATTCTGGGCATCTGGAGCACAGAAAAAGGTC
AGGTGATCTTTGTTGATGCACCGGGTTTGATCAAAGCTGATGAAGGTTTGAATGGTTTCCTGGCACAGGAAGCCCATGAT
GTTATCAACAGCTCTGATGCTTTGCTGGCGATCATTGCCGTGGATGAGGAAAAACCGGAAAACGCAGAAAAGGTCATCGA
CCTGGTTTCCAAAAGCGGCAAACCATGGATCGCCGTGATCACCAAAACGGATATCGAGGAAAAAGCCCACCGTGTGATGA
TTCTTCGCAAGATGGTCGAGGACAAGGGCGGCAAAGCCTTCTCTGTGTCCGTGAAAGATTCCAAAAACGACCAGGAAGAG
CGTGAAGCACTTCTGATTGAGTTCATGGAATTGCTGCCAGAATCTCCGGCGCCTTTGTATGACACTGAGTTGTTTACAAA
TGAAAACGTGCGTGAAATGGCCGCGGAAATCGTCCGTGAGCAGTGCTTTGAGGCCCTTCACCACGAAATCCCGTATTCTA
TCGCGGTTCGTATCGTGAAGTTTGAAGAGGACGCGAAGCCGGTTCCAAAGATCTATGCAGAGATCGTGGTGTCCAAAGAC
AGCCACAAGGCGATCGTGATCGGAAAAGGCGCCAGCGTGATCAAACAGATCGGTATGGAAGCCCGCAAGGAAATTGAAAA
ACTGATGGGAGAGAAAATCTTCCTGGACCTGAACGTGGCATCCAAGCCCGAGTGGTTCTCCAATAAACGCATGATGAAGG
AGCTTGGATATGTCGTCGACTCTAAAGACTGA

Upstream 100 bases:

>100_bases
GAAGATGTCTGGGCTCAAGGGCGGGGCCGCAGTAAGAAAAACGCCGAACAAATGGCGGCAAAGAATGCCCTTGAGATGAA
GTACAAGGAGACGAATTAAG

Downstream 100 bases:

>100_bases
TTTCTCGCCGAAAGTGGCGATCATCGGTCGCCCGAATGTCGGTAAATCAACACTGTTTAATATCATCACTGAAACCCGCA
AAGCCGTGGTGAAAAACCAG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSYKAGFLGLIGQPNAGKSTLMNFLVDEKVSIVSSKPQTTRRRILGIWSTEKGQVIFVDAPGLIKADEGLNGFLAQEAHD
VINSSDALLAIIAVDEEKPENAEKVIDLVSKSGKPWIAVITKTDIEEKAHRVMILRKMVEDKGGKAFSVSVKDSKNDQEE
REALLIEFMELLPESPAPLYDTELFTNENVREMAAEIVREQCFEALHHEIPYSIAVRIVKFEEDAKPVPKIYAEIVVSKD
SHKAIVIGKGASVIKQIGMEARKEIEKLMGEKIFLDLNVASKPEWFSNKRMMKELGYVVDSKD

Sequences:

>Translated_303_residues
MSYKAGFLGLIGQPNAGKSTLMNFLVDEKVSIVSSKPQTTRRRILGIWSTEKGQVIFVDAPGLIKADEGLNGFLAQEAHD
VINSSDALLAIIAVDEEKPENAEKVIDLVSKSGKPWIAVITKTDIEEKAHRVMILRKMVEDKGGKAFSVSVKDSKNDQEE
REALLIEFMELLPESPAPLYDTELFTNENVREMAAEIVREQCFEALHHEIPYSIAVRIVKFEEDAKPVPKIYAEIVVSKD
SHKAIVIGKGASVIKQIGMEARKEIEKLMGEKIFLDLNVASKPEWFSNKRMMKELGYVVDSKD
>Mature_302_residues
SYKAGFLGLIGQPNAGKSTLMNFLVDEKVSIVSSKPQTTRRRILGIWSTEKGQVIFVDAPGLIKADEGLNGFLAQEAHDV
INSSDALLAIIAVDEEKPENAEKVIDLVSKSGKPWIAVITKTDIEEKAHRVMILRKMVEDKGGKAFSVSVKDSKNDQEER
EALLIEFMELLPESPAPLYDTELFTNENVREMAAEIVREQCFEALHHEIPYSIAVRIVKFEEDAKPVPKIYAEIVVSKDS
HKAIVIGKGASVIKQIGMEARKEIEKLMGEKIFLDLNVASKPEWFSNKRMMKELGYVVDSKD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=31.8936877076412, Blast_Score=140, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33845; Mature: 33713

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKAGFLGLIGQPNAGKSTLMNFLVDEKVSIVSSKPQTTRRRILGIWSTEKGQVIFVDA
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEECCCCCEEEEEC
PGLIKADEGLNGFLAQEAHDVINSSDALLAIIAVDEEKPENAEKVIDLVSKSGKPWIAVI
CCCEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEE
TKTDIEEKAHRVMILRKMVEDKGGKAFSVSVKDSKNDQEEREALLIEFMELLPESPAPLY
ECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC
DTELFTNENVREMAAEIVREQCFEALHHEIPYSIAVRIVKFEEDAKPVPKIYAEIVVSKD
CCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCCHHHHHHHHHCCCC
SHKAIVIGKGASVIKQIGMEARKEIEKLMGEKIFLDLNVASKPEWFSNKRMMKELGYVVD
CCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
SKD
CCC
>Mature Secondary Structure 
SYKAGFLGLIGQPNAGKSTLMNFLVDEKVSIVSSKPQTTRRRILGIWSTEKGQVIFVDA
CCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEECCCCCEEEEEC
PGLIKADEGLNGFLAQEAHDVINSSDALLAIIAVDEEKPENAEKVIDLVSKSGKPWIAVI
CCCEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEE
TKTDIEEKAHRVMILRKMVEDKGGKAFSVSVKDSKNDQEEREALLIEFMELLPESPAPLY
ECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC
DTELFTNENVREMAAEIVREQCFEALHHEIPYSIAVRIVKFEEDAKPVPKIYAEIVVSKD
CCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCCHHHHHHHHHCCCC
SHKAIVIGKGASVIKQIGMEARKEIEKLMGEKIFLDLNVASKPEWFSNKRMMKELGYVVD
CCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
SKD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA