Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 42523409

GI number: 42523409

Start: 1843472

End: 1844845

Strand: Direct

Name: glmM

Synonym: Bd1931

Alternate gene names: 42523409

Gene position: 1843472-1844845 (Clockwise)

Preceding gene: 42523408

Following gene: 42523410

Centisome position: 48.73

GC content: 50.29

Gene sequence:

>1374_bases
GTGGAAAAGAAAACAAGACTGTTTGGAACTGATGGTATTCGCGGGACTGCGAATCAGTATCCGATGACTCCGGATATGGT
TGTGAAGATCGGTCAAGCCATTGGTTATCTTTTGCGTAAAGAAGCTGAAGAAAAATCCTCCAGCGTGCGCAAAGTGGTTA
TTGGAAAAGACACGCGTTTGTCCGGTTATATGATCGAGCAGGCCTTGGCTTCTGGTTTGAACTCCATGGGTGTGTTCGTG
CAACTGGTGGGACCACTGCCGACTCCGGGTATCGGTTACTTGACCAGAACGATGCGTGCGGCGGCGGGGATCGTGATCTC
GGCGTCTCACAATCCATTCCATGATAATGGGATCAAAGTGTTTGGTTCTGATGGTTTTAAAATCTCTGAAGAGATGGAGC
GTGAAATCGAGCGTCTGGTGCTTGAAGAAGACCTGACGCCACTTCTGCCTCCAAGCAAAGAAATCGGCCGCACTCGCCGT
ATCGAAGACTCCCAGGGTCGTTATATCGTTTACGTGAAAGGCACATTCCCTCTGGAGTATACTCTGGATGGTATGCGTAT
CGTATTGGATACGGCCAACGGGGCTTCATACAAAGTTGCTCCATCCATCTTCCAGGAGCTGGGTGCGGAAGTCATCCAGC
TGGGTGATGATCCCAATGGCACAAACATCAATGACAAAGTCGGTGCTTTGTATCCACAAAAGCTGGCTGAATCCGTTTTG
CACTATCGTGCGGACGTGGGCATCAGTTTGGATGGGGATGCGGACCGTGTGATCATGGTGGATGAAAAGGGCGAGATCGT
AAACGGAGACCGTATTTTGGCGATCTGTGCTTTGCACATGAAAGAGCGTGGCTTGCTGAAAGGTGACACTCTGGTGGCAA
CTCAGATGTCAAACTTCGGTCTTGAAAAGCGCATGAATGAAGCGGGCATCAAGCTTGTGAAAACCGGCGTAGGTGACAAG
TACGTGGTCGAAGAAATGCGTAAACACGGTTACAACCTGGGTGGCGAGCAGTCTGGCCACATCATCTTCCTGGATCACAC
CACAACGGGGGATGGCTGTATCGCGGCGTTGAGTGTTCTGGCGGTGATGAAACAAACTGGCAAGAAGATGAGCGATCTGA
ATCACGTCTTTGAGGACGTTCCGCAAATCCTGATCAACTGCCGTGTAAAACGCCGTGCCGAGCTTTCTGAGCTTGCCGGC
TACAATGACATGATTCGCAATATTGAAAAGAAACTGGCTGGCAATGGCCGCGTCTTCGTTCGTTTCTCTGGCACCGAGCC
GGTGATTCGTGTGTTGGTCGAGGGAACTGAAAAAGCTCAGATCACTCAATTCGCGGAAGAAATCGCCTCTTTCCTGGAAA
AAGAACTGTCTTAA

Upstream 100 bases:

>100_bases
CCGCTGGGTGTGCGAATTCTGGGTGTCCGTCCAAATCAAATTCAAGCTGAAGTGTTGCAGATAAAGGAAAAGCCCCGTGA
CGAACAAGAAAGCCGATAAA

Downstream 100 bases:

>100_bases
TTAAAGGGGGATGGCAGTTCTGCCATCCTAAAAATCTATGAAACATAAAATTCGTTTGGGTGTAAATGTGGACCACGTGG
CGACGCTTCGTCAGGTGCGT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MEKKTRLFGTDGIRGTANQYPMTPDMVVKIGQAIGYLLRKEAEEKSSSVRKVVIGKDTRLSGYMIEQALASGLNSMGVFV
QLVGPLPTPGIGYLTRTMRAAAGIVISASHNPFHDNGIKVFGSDGFKISEEMEREIERLVLEEDLTPLLPPSKEIGRTRR
IEDSQGRYIVYVKGTFPLEYTLDGMRIVLDTANGASYKVAPSIFQELGAEVIQLGDDPNGTNINDKVGALYPQKLAESVL
HYRADVGISLDGDADRVIMVDEKGEIVNGDRILAICALHMKERGLLKGDTLVATQMSNFGLEKRMNEAGIKLVKTGVGDK
YVVEEMRKHGYNLGGEQSGHIIFLDHTTTGDGCIAALSVLAVMKQTGKKMSDLNHVFEDVPQILINCRVKRRAELSELAG
YNDMIRNIEKKLAGNGRVFVRFSGTEPVIRVLVEGTEKAQITQFAEEIASFLEKELS

Sequences:

>Translated_457_residues
MEKKTRLFGTDGIRGTANQYPMTPDMVVKIGQAIGYLLRKEAEEKSSSVRKVVIGKDTRLSGYMIEQALASGLNSMGVFV
QLVGPLPTPGIGYLTRTMRAAAGIVISASHNPFHDNGIKVFGSDGFKISEEMEREIERLVLEEDLTPLLPPSKEIGRTRR
IEDSQGRYIVYVKGTFPLEYTLDGMRIVLDTANGASYKVAPSIFQELGAEVIQLGDDPNGTNINDKVGALYPQKLAESVL
HYRADVGISLDGDADRVIMVDEKGEIVNGDRILAICALHMKERGLLKGDTLVATQMSNFGLEKRMNEAGIKLVKTGVGDK
YVVEEMRKHGYNLGGEQSGHIIFLDHTTTGDGCIAALSVLAVMKQTGKKMSDLNHVFEDVPQILINCRVKRRAELSELAG
YNDMIRNIEKKLAGNGRVFVRFSGTEPVIRVLVEGTEKAQITQFAEEIASFLEKELS
>Mature_457_residues
MEKKTRLFGTDGIRGTANQYPMTPDMVVKIGQAIGYLLRKEAEEKSSSVRKVVIGKDTRLSGYMIEQALASGLNSMGVFV
QLVGPLPTPGIGYLTRTMRAAAGIVISASHNPFHDNGIKVFGSDGFKISEEMEREIERLVLEEDLTPLLPPSKEIGRTRR
IEDSQGRYIVYVKGTFPLEYTLDGMRIVLDTANGASYKVAPSIFQELGAEVIQLGDDPNGTNINDKVGALYPQKLAESVL
HYRADVGISLDGDADRVIMVDEKGEIVNGDRILAICALHMKERGLLKGDTLVATQMSNFGLEKRMNEAGIKLVKTGVGDK
YVVEEMRKHGYNLGGEQSGHIIFLDHTTTGDGCIAALSVLAVMKQTGKKMSDLNHVFEDVPQILINCRVKRRAELSELAG
YNDMIRNIEKKLAGNGRVFVRFSGTEPVIRVLVEGTEKAQITQFAEEIASFLEKELS

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=445, Percent_Identity=47.8651685393258, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI1788361, Length=454, Percent_Identity=28.6343612334802, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17864244, Length=405, Percent_Identity=24.6913580246914, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_BDEBA (Q6MLS4)

Other databases:

- EMBL:   BX842651
- RefSeq:   NP_968789.1
- ProteinModelPortal:   Q6MLS4
- GeneID:   2734665
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd1931
- NMPDR:   fig|264462.1.peg.1760
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- PhylomeDB:   Q6MLS4
- BioCyc:   BBAC264462:BD1931-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 50212; Mature: 50212

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 109-109

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKTRLFGTDGIRGTANQYPMTPDMVVKIGQAIGYLLRKEAEEKSSSVRKVVIGKDTRL
CCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
SGYMIEQALASGLNSMGVFVQLVGPLPTPGIGYLTRTMRAAAGIVISASHNPFHDNGIKV
HHHHHHHHHHCCCCHHCCHHEEECCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCEEE
FGSDGFKISEEMEREIERLVLEEDLTPLLPPSKEIGRTRRIEDSQGRYIVYVKGTFPLEY
ECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCEEEEEEECCCEEE
TLDGMRIVLDTANGASYKVAPSIFQELGAEVIQLGDDPNGTNINDKVGALYPQKLAESVL
EECCEEEEEECCCCCCEEECHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHH
HYRADVGISLDGDADRVIMVDEKGEIVNGDRILAICALHMKERGLLKGDTLVATQMSNFG
HHHHCCCEEECCCCCEEEEEECCCCEECCCCEEEHHHHHHHHCCCCCCCEEEEEHHHHCC
LEKRMNEAGIKLVKTGVGDKYVVEEMRKHGYNLGGEQSGHIIFLDHTTTGDGCIAALSVL
HHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHH
AVMKQTGKKMSDLNHVFEDVPQILINCRVKRRAELSELAGYNDMIRNIEKKLAGNGRVFV
HHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEE
RFSGTEPVIRVLVEGTEKAQITQFAEEIASFLEKELS
EECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKKTRLFGTDGIRGTANQYPMTPDMVVKIGQAIGYLLRKEAEEKSSSVRKVVIGKDTRL
CCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
SGYMIEQALASGLNSMGVFVQLVGPLPTPGIGYLTRTMRAAAGIVISASHNPFHDNGIKV
HHHHHHHHHHCCCCHHCCHHEEECCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCEEE
FGSDGFKISEEMEREIERLVLEEDLTPLLPPSKEIGRTRRIEDSQGRYIVYVKGTFPLEY
ECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCEEEEEEECCCEEE
TLDGMRIVLDTANGASYKVAPSIFQELGAEVIQLGDDPNGTNINDKVGALYPQKLAESVL
EECCEEEEEECCCCCCEEECHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHH
HYRADVGISLDGDADRVIMVDEKGEIVNGDRILAICALHMKERGLLKGDTLVATQMSNFG
HHHHCCCEEECCCCCEEEEEECCCCEECCCCEEEHHHHHHHHCCCCCCCEEEEEHHHHCC
LEKRMNEAGIKLVKTGVGDKYVVEEMRKHGYNLGGEQSGHIIFLDHTTTGDGCIAALSVL
HHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHH
AVMKQTGKKMSDLNHVFEDVPQILINCRVKRRAELSELAGYNDMIRNIEKKLAGNGRVFV
HHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEE
RFSGTEPVIRVLVEGTEKAQITQFAEEIASFLEKELS
EECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA