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The map label for this gene is kdpE [H]

Identifier: 42523251

GI number: 42523251

Start: 1696430

End: 1697122

Strand: Direct

Name: kdpE [H]

Synonym: Bd1759

Alternate gene names: 42523251

Gene position: 1696430-1697122 (Clockwise)

Preceding gene: 42523250

Following gene: 42523253

Centisome position: 44.84

GC content: 52.38

Gene sequence:

>693_bases
ATGAAAGAGAACTTGAAGAAAGTTTTGGTGATTGATGATGAAGCCTCCATCCGTAAGCTTTTGCGGGTGAGTCTGGAAGC
CAACGCCTATCAGGTGGAAGAGGCTCCCAGCGGGCGAGACGGGTTGGCGGCGGCGGCGTCATTGCGACCGGATCTGGTTC
TTTTGGATCTGGGCCTGCCGGATATGACAGGGCTGCATGTGCTGTCGGAGCTGCGCAGTTGGTCTAAAGTGCCGGTGATT
GTTTTAACTGTGCAGGATTCCGACAATGATAAGATTGCCGCTTTGGATGGCGGCGCGGATGATTACATCACCAAACCTTT
TAGTGTGCCGGAGCTGTTGGTGCGCATGCGTGTGGCTTTAAGGCATTCACCGCAGAACGCCGCTGAAAAAACCGAGATGG
TCAGTGGGCCGTTGAAAGTGGATGTTCCCGGTCACACCGTGACGGTGGAAGGGGAGCTCGTTAAGCTGACCGCGACCGAG
TTTAATATTTTAAAAGTGCTGATCAAAAACAAAGACAAAGTGGTCACCCATCGCATGCTTTTAAATGAAGTCTGGGGGCC
TAATTCTGTGGAGCACACTCATTATTTGAGGGTGTATGTGGGCGGTTTGCGTAAGAAGCTTCACATCCGAGAGGAGTTGG
CCGAGATCATCGTCACAGAAGCCGGCGTTGGATACCGGCTGCTGGATCTTTAG

Upstream 100 bases:

>100_bases
GCGGCAGGGTCTATGCTCAGAATCGCAAGGATAGGTCCGGAGCGGAGTTCGTCGTGGAACTTCCCTACGAGAGTCCTCCT
GCGGATTTAGAGGACGGAAG

Downstream 100 bases:

>100_bases
ATTACTTTTTCAGGATGGATTTTTTAAGGGTGGCTACGCCATCGTCAGAAGGCTTGCCCAGCCAGATGGAGAAGATCTTT
TCGATGAATCCCGCCGGACC

Product: two-component response regulator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKENLKKVLVIDDEASIRKLLRVSLEANAYQVEEAPSGRDGLAAAASLRPDLVLLDLGLPDMTGLHVLSELRSWSKVPVI
VLTVQDSDNDKIAALDGGADDYITKPFSVPELLVRMRVALRHSPQNAAEKTEMVSGPLKVDVPGHTVTVEGELVKLTATE
FNILKVLIKNKDKVVTHRMLLNEVWGPNSVEHTHYLRVYVGGLRKKLHIREELAEIIVTEAGVGYRLLDL

Sequences:

>Translated_230_residues
MKENLKKVLVIDDEASIRKLLRVSLEANAYQVEEAPSGRDGLAAAASLRPDLVLLDLGLPDMTGLHVLSELRSWSKVPVI
VLTVQDSDNDKIAALDGGADDYITKPFSVPELLVRMRVALRHSPQNAAEKTEMVSGPLKVDVPGHTVTVEGELVKLTATE
FNILKVLIKNKDKVVTHRMLLNEVWGPNSVEHTHYLRVYVGGLRKKLHIREELAEIIVTEAGVGYRLLDL
>Mature_230_residues
MKENLKKVLVIDDEASIRKLLRVSLEANAYQVEEAPSGRDGLAAAASLRPDLVLLDLGLPDMTGLHVLSELRSWSKVPVI
VLTVQDSDNDKIAALDGGADDYITKPFSVPELLVRMRVALRHSPQNAAEKTEMVSGPLKVDVPGHTVTVEGELVKLTATE
FNILKVLIKNKDKVVTHRMLLNEVWGPNSVEHTHYLRVYVGGLRKKLHIREELAEIIVTEAGVGYRLLDL

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=46.875, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=34.3891402714932, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=34.3478260869565, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.0807174887892, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=32.15859030837, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=32.8828828828829, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=32.2869955156951, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=29.7297297297297, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=31.0043668122271, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=29.4117647058824, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=31.7596566523605, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=31.2775330396476, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.9559471365639, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788550, Length=159, Percent_Identity=28.9308176100629, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=30.5343511450382, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693140, Length=215, Percent_Identity=26.9767441860465, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=123, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=33.6363636363636, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788521, Length=217, Percent_Identity=28.110599078341, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25436; Mature: 25436

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENLKKVLVIDDEASIRKLLRVSLEANAYQVEEAPSGRDGLAAAASLRPDLVLLDLGLP
CCCCCCEEEEECCCHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHCCCCCEEEEECCCC
DMTGLHVLSELRSWSKVPVIVLTVQDSDNDKIAALDGGADDYITKPFSVPELLVRMRVAL
CHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
RHSPQNAAEKTEMVSGPLKVDVPGHTVTVEGELVKLTATEFNILKVLIKNKDKVVTHRML
HCCCCCHHHHHHHHCCCEEEECCCCEEEECCEEEEEEECHHHHHHHHHCCCCHHHHHHHH
LNEVWGPNSVEHTHYLRVYVGGLRKKLHIREELAEIIVTEAGVGYRLLDL
HHHCCCCCCCCHHEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MKENLKKVLVIDDEASIRKLLRVSLEANAYQVEEAPSGRDGLAAAASLRPDLVLLDLGLP
CCCCCCEEEEECCCHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHCCCCCEEEEECCCC
DMTGLHVLSELRSWSKVPVIVLTVQDSDNDKIAALDGGADDYITKPFSVPELLVRMRVAL
CHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
RHSPQNAAEKTEMVSGPLKVDVPGHTVTVEGELVKLTATEFNILKVLIKNKDKVVTHRML
HCCCCCHHHHHHHHCCCEEEECCCCEEEECCEEEEEEECHHHHHHHHHCCCCHHHHHHHH
LNEVWGPNSVEHTHYLRVYVGGLRKKLHIREELAEIIVTEAGVGYRLLDL
HHHCCCCCCCCHHEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]