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The map label for this gene is ilvE [H]

Identifier: 42523231

GI number: 42523231

Start: 1670684

End: 1671658

Strand: Direct

Name: ilvE [H]

Synonym: Bd1736

Alternate gene names: 42523231

Gene position: 1670684-1671658 (Clockwise)

Preceding gene: 42523226

Following gene: 42523234

Centisome position: 44.16

GC content: 50.36

Gene sequence:

>975_bases
ATGAATCTACCCATTCTTTCTTCTGCGGATGTTCAGGCCCAACTTTTAAAGCGACAATACCAGGCTCAAGGCAGCTATCT
GGCGATGTACAGCAGCTGGTATGGCGGGGTGATTAAAGACCCGGGGCTGATGATGGTGCCGGTGGATGATCACCTTGTGC
ACCGCGGGGATGGTGTCTTTGAGGCGATCAAAGTCGTGGATGGTCAGGTGTTTTTGATGCAAGAGCATCTGGAGCGTCTG
CAGTCTTCCGCCCAGCAGATCGGTATCAGTCTGCCGCACAGCCTGGAAGACATGAAAAAGATTATTCTCGAAACCACGCG
CATTGCCGGCGCGCCTTATGCAGTTTTGCGCCTGTATATTTCCCGTGGTCCGGGGTATTTTACGACAAATCCTTACGATT
CCATCAGCTCGCAGATGTATTTGATTGTGACTTCGTTTACGCCGTTAACAGATGAAAAGTACTTGAAGGGCGTGAAGGTC
GGGCGCAGTCAGATTGTTCCCAAAGACCCGTGGCTGGCTCGGATTAAGACCTGCAATTATTTGCCGAACGTAATGATGAA
AAAAGAAAGTGTGGACCGCAAGATCGACTTCACCATCGGCATTGATCCGCAAGGGTTCATCACGGAAGGCAGCACGGAAA
ACATCGTTCTGATTGATAAAGACAAAAACCTGCTTCGCCCAAAACTGCGCCAAATTCTGAAAGGCACAACCATGATGCGC
ACCTTTGATCTGGCTGAAAGCCTGTTGGCGTCGGGGGAGTTAAAGTCCATCCAGGAAAAGGATCTGACCGAGCAGGATAT
TCTCAGCGCATCTGAAGCCATGATGATCGGAACAACTTTGGATGTGTTGCCAGTGACCGAATACGAAGGTCAGCAGATTG
GCGAGGGCAAACAAGGAGCGCTCGCGTTTAAGCTTTTGCAGCTGCTCCGCGAGGATATGAAAAAGGGGCCGAAAACGACC
CCTGTAAAGTTCTAA

Upstream 100 bases:

>100_bases
AGGACCTCCCTTGGGAATGGTCAAATTAAAAACAAAAAAAACTTCACGCCGAACCGACGTGAATCTAGAATGAAACGGTG
ATTTTTTAATAAGGACGTTT

Downstream 100 bases:

>100_bases
ACTTCCAACTGAATTTTATCGAGCAGTTCTGGATCACTCAGCACTGCTTCGCCGCCCTTGGCGATCGCCGTCAGCGGGTC
ATCCGCGATGCGAACCTGCA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MNLPILSSADVQAQLLKRQYQAQGSYLAMYSSWYGGVIKDPGLMMVPVDDHLVHRGDGVFEAIKVVDGQVFLMQEHLERL
QSSAQQIGISLPHSLEDMKKIILETTRIAGAPYAVLRLYISRGPGYFTTNPYDSISSQMYLIVTSFTPLTDEKYLKGVKV
GRSQIVPKDPWLARIKTCNYLPNVMMKKESVDRKIDFTIGIDPQGFITEGSTENIVLIDKDKNLLRPKLRQILKGTTMMR
TFDLAESLLASGELKSIQEKDLTEQDILSASEAMMIGTTLDVLPVTEYEGQQIGEGKQGALAFKLLQLLREDMKKGPKTT
PVKF

Sequences:

>Translated_324_residues
MNLPILSSADVQAQLLKRQYQAQGSYLAMYSSWYGGVIKDPGLMMVPVDDHLVHRGDGVFEAIKVVDGQVFLMQEHLERL
QSSAQQIGISLPHSLEDMKKIILETTRIAGAPYAVLRLYISRGPGYFTTNPYDSISSQMYLIVTSFTPLTDEKYLKGVKV
GRSQIVPKDPWLARIKTCNYLPNVMMKKESVDRKIDFTIGIDPQGFITEGSTENIVLIDKDKNLLRPKLRQILKGTTMMR
TFDLAESLLASGELKSIQEKDLTEQDILSASEAMMIGTTLDVLPVTEYEGQQIGEGKQGALAFKLLQLLREDMKKGPKTT
PVKF
>Mature_324_residues
MNLPILSSADVQAQLLKRQYQAQGSYLAMYSSWYGGVIKDPGLMMVPVDDHLVHRGDGVFEAIKVVDGQVFLMQEHLERL
QSSAQQIGISLPHSLEDMKKIILETTRIAGAPYAVLRLYISRGPGYFTTNPYDSISSQMYLIVTSFTPLTDEKYLKGVKV
GRSQIVPKDPWLARIKTCNYLPNVMMKKESVDRKIDFTIGIDPQGFITEGSTENIVLIDKDKNLLRPKLRQILKGTTMMR
TFDLAESLLASGELKSIQEKDLTEQDILSASEAMMIGTTLDVLPVTEYEGQQIGEGKQGALAFKLLQLLREDMKKGPKTT
PVKF

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=246, Percent_Identity=27.6422764227642, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI48994963, Length=288, Percent_Identity=25.6944444444444, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 36267; Mature: 36267

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPILSSADVQAQLLKRQYQAQGSYLAMYSSWYGGVIKDPGLMMVPVDDHLVHRGDGVF
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHCCCEECCCCEEEEECCHHHHCCCCCHH
EAIKVVDGQVFLMQEHLERLQSSAQQIGISLPHSLEDMKKIILETTRIAGAPYAVLRLYI
HHHHHHCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
SRGPGYFTTNPYDSISSQMYLIVTSFTPLTDEKYLKGVKVGRSQIVPKDPWLARIKTCNY
HCCCCCCCCCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHCHHHCCCCCCHHHHHHHHHH
LPNVMMKKESVDRKIDFTIGIDPQGFITEGSTENIVLIDKDKNLLRPKLRQILKGTTMMR
HHHHHHHHHCCCCEEEEEEECCCCCCEECCCCCEEEEEECCCHHHHHHHHHHHCCHHHHH
TFDLAESLLASGELKSIQEKDLTEQDILSASEAMMIGTTLDVLPVTEYEGQQIGEGKQGA
HHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCEEEECEEEEEECCCCCCCCCCCCCCHH
LAFKLLQLLREDMKKGPKTTPVKF
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNLPILSSADVQAQLLKRQYQAQGSYLAMYSSWYGGVIKDPGLMMVPVDDHLVHRGDGVF
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHCCCEECCCCEEEEECCHHHHCCCCCHH
EAIKVVDGQVFLMQEHLERLQSSAQQIGISLPHSLEDMKKIILETTRIAGAPYAVLRLYI
HHHHHHCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
SRGPGYFTTNPYDSISSQMYLIVTSFTPLTDEKYLKGVKVGRSQIVPKDPWLARIKTCNY
HCCCCCCCCCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHCHHHCCCCCCHHHHHHHHHH
LPNVMMKKESVDRKIDFTIGIDPQGFITEGSTENIVLIDKDKNLLRPKLRQILKGTTMMR
HHHHHHHHHCCCCEEEEEEECCCCCCEECCCCCEEEEEECCCHHHHHHHHHHHCCHHHHH
TFDLAESLLASGELKSIQEKDLTEQDILSASEAMMIGTTLDVLPVTEYEGQQIGEGKQGA
HHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCEEEECEEEEEECCCCCCCCCCCCCCHH
LAFKLLQLLREDMKKGPKTTPVKF
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]