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The map label for this gene is neuA [H]

Identifier: 42523183

GI number: 42523183

Start: 1622710

End: 1623402

Strand: Direct

Name: neuA [H]

Synonym: Bd1686

Alternate gene names: 42523183

Gene position: 1622710-1623402 (Clockwise)

Preceding gene: 42523182

Following gene: 42523184

Centisome position: 42.9

GC content: 40.26

Gene sequence:

>693_bases
TTGAAGGGTACTTCGGTGGGTAGCTTAGCTATAATACCAGCACGAGCTGGATCGAGAAGATTGCCAGGGAAGAACAAGAG
GAATTTTGCTGGAAAACCTTTGGTTCAATGGACGATAGAAGCGGCTTTAGATTCTTCTGAATTTAGTTGTATTGTTGTTT
CAAGTGACGATTTGGATGTGTTGTCATTGGTTGAGAAGTTTCCTTCTGTGCTTTTTTTGGAGCGTGATCCACGACTATCA
AGCGATAGTGCAACAAGTGTTGATGTAATGTTGGATGTTATTGATAGGGTTGGTGCAAAATTTCAGACTGTAACACTTTT
GCAGCCGACCTCGCCTCTGCGTGATAGTGATTGTATTCGAAATGCATTTTCATTTTATCGGAGTTGTGGTTTTAAACAGG
TAGTTAGCGCAAGGGATTTAAAAGAAAATGTTAACCACTTGGCGGTGGTAACAGATGGCAAATTAAATAGAATCGCGAGT
GATAAACTATTTATGACTGAAGGAAGTAGTTTAGTTGCTCTTAATGGTGCGATTTATATATCGGAGTTCGATTATTTTAG
GGCAATGAAGTCTTTGTTTACTGAAAGCACGACTGCTTTTTTGATGGAGGCGCTTATCTCAATTGATATTGACTACGAAG
ATGACTGGCAAAAAGCAGAATCGGTTGCGCTAGCACTTGGTAAGGCGAAGTAG

Upstream 100 bases:

>100_bases
TCCCTTAAGGACAAAGAAAAATTGATACAGAGTTTTAAACTTAAAGATTACTGGGTCGACATCGGTAGGCTGGAAGATTT
TCATAAAGCTCAGTCTGATT

Downstream 100 bases:

>100_bases
GTGGACGAGGCATTAGTATCCTTTTTTTTGAGTGGCAGTCTCAACGGATTCGCATATTTTATTGAAAGGCAGCTTTTATG
AATGATAATTGGGGTAAAAT

Product: acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKGTSVGSLAIIPARAGSRRLPGKNKRNFAGKPLVQWTIEAALDSSEFSCIVVSSDDLDVLSLVEKFPSVLFLERDPRLS
SDSATSVDVMLDVIDRVGAKFQTVTLLQPTSPLRDSDCIRNAFSFYRSCGFKQVVSARDLKENVNHLAVVTDGKLNRIAS
DKLFMTEGSSLVALNGAIYISEFDYFRAMKSLFTESTTAFLMEALISIDIDYEDDWQKAESVALALGKAK

Sequences:

>Translated_230_residues
MKGTSVGSLAIIPARAGSRRLPGKNKRNFAGKPLVQWTIEAALDSSEFSCIVVSSDDLDVLSLVEKFPSVLFLERDPRLS
SDSATSVDVMLDVIDRVGAKFQTVTLLQPTSPLRDSDCIRNAFSFYRSCGFKQVVSARDLKENVNHLAVVTDGKLNRIAS
DKLFMTEGSSLVALNGAIYISEFDYFRAMKSLFTESTTAFLMEALISIDIDYEDDWQKAESVALALGKAK
>Mature_230_residues
MKGTSVGSLAIIPARAGSRRLPGKNKRNFAGKPLVQWTIEAALDSSEFSCIVVSSDDLDVLSLVEKFPSVLFLERDPRLS
SDSATSVDVMLDVIDRVGAKFQTVTLLQPTSPLRDSDCIRNAFSFYRSCGFKQVVSARDLKENVNHLAVVTDGKLNRIAS
DKLFMTEGSSLVALNGAIYISEFDYFRAMKSLFTESTTAFLMEALISIDIDYEDDWQKAESVALALGKAK

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=229, Percent_Identity=29.2576419213974, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087 [H]

Pfam domain/function: PF02348 CTP_transf_3; PF00657 Lipase_GDSL [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 25264; Mature: 25264

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTSVGSLAIIPARAGSRRLPGKNKRNFAGKPLVQWTIEAALDSSEFSCIVVSSDDLDV
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHEEEHHHHCCCCCCEEEEECCCCHHH
LSLVEKFPSVLFLERDPRLSSDSATSVDVMLDVIDRVGAKFQTVTLLQPTSPLRDSDCIR
HHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHH
NAFSFYRSCGFKQVVSARDLKENVNHLAVVTDGKLNRIASDKLFMTEGSSLVALNGAIYI
HHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCEEEEECCCEEEEECCEEEE
SEFDYFRAMKSLFTESTTAFLMEALISIDIDYEDDWQKAESVALALGKAK
EHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKGTSVGSLAIIPARAGSRRLPGKNKRNFAGKPLVQWTIEAALDSSEFSCIVVSSDDLDV
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHEEEHHHHCCCCCCEEEEECCCCHHH
LSLVEKFPSVLFLERDPRLSSDSATSVDVMLDVIDRVGAKFQTVTLLQPTSPLRDSDCIR
HHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHH
NAFSFYRSCGFKQVVSARDLKENVNHLAVVTDGKLNRIASDKLFMTEGSSLVALNGAIYI
HHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCEEEEECCCEEEEECCEEEE
SEFDYFRAMKSLFTESTTAFLMEALISIDIDYEDDWQKAESVALALGKAK
EHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10464185 [H]