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The map label for this gene is neuB

Identifier: 42523180

GI number: 42523180

Start: 1619936

End: 1621006

Strand: Direct

Name: neuB

Synonym: Bd1683

Alternate gene names: NA

Gene position: 1619936-1621006 (Clockwise)

Preceding gene: 42523179

Following gene: 42523181

Centisome position: 42.82

GC content: 43.04

Gene sequence:

>1071_bases
ATGACATATATCATTGCAGAAGCTGGCGTAAATCATAATGGTTCGTTGGAGATGGCCAAAAAACTTGTTGATGTTGCGAA
AGAATCTGGTGCAGATGCCGTAAAGTTTCAAACGTTTAAAGCAGAGAATATTGTCAGCAAAAAAGCTCCAAAAGCAGACT
ACCAAGTTGAAACGACAGGTAATAATGAGACTCAGCTTCAGATGATTCAAAAGCTAGAGCTCGACGAGGAAGCGCATGCC
GTTTTGGTCGAGTATTGCAAAAAGAAGGGAATTGATTTTCTTTCAACACCATTTGATATCCCGAGCGTAGGACTATTGGC
GAAGAAAATGGGTGTGCCTCGTTTAAAAGTGCCTTCTGGTGAGATTATCAATGCTCCGCTGCTTTTGAAGGTGGCGCAAA
CAAATCTCCCAGTAATTGTTTCCACGGGAATGGCTACTTTGGGAGAAATTGAAGCAGCTTTGGGTGTATTGGCTTTCGGT
TATCTGGGATCAAAAGAGCAACCATCAGTTCGTCAATTCCAAAATGCATTTATCAGTGAAGAGGGGCGTAGGAAGCTATC
TGAAAAGGTCACGATTTTACATTGCACCACTGACTATCCAGCAAAGCTTGAAGAAGTAAATCTGAATGCAATGTTGACGA
TCAAAAATGCTTTTGGTCTGCCAATTGGTTACTCGGATCATACTGTTGGAATTTCTGTGGCGATTGCAGCCGTAGCAATG
GGGGCCACGTTAATTGAAAAGCACTTCACTTTAGATAGAAATCTGCCGGGGCCGGATCATAGAGCCTCGTTGGAGCCTCA
GGAATTGAAAAATATGGTTGATGGCATCAGAGCTGTTGAGAAAGCCAAAGGCTCCTTTGTCAAAGGTCCAACACCCGCTG
AAGTTTTGAATCGTGCGGTTGTTAGAAGAAGTCTTGTCGCAAAAGCAGAGATTCAGGTAAATGAAAGGTTTAGTGAGAAT
AATCTTGATGCGAAAAGGCCGGGTACTGGGGTTTCACCAATGTTGTTTTGGGAGTATTTGAGTAAGTCTTCTTCCAAGGC
TTACGCCGTGGACGATTTGATTGAGGATTAA

Upstream 100 bases:

>100_bases
ATCCACGTAGTGCTGAAGCAATTAAGTCTCTCGCTCAGCTTCGTGGCTCGACTGCGGGAGTAAAGAATGCAGAAAGCTTT
CAGTTAATTAGGGAGATACT

Downstream 100 bases:

>100_bases
TATATATGTCTGTTGCGGGAACAATTGTTTTGGGTGCAGGCGGGCATTCAAAAGTTGTGGTTGACACCTTAATTGCCAGT
TCTGTTGTTGTTGTTGGTCT

Product: putative N-acetylneuraminic acid synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTYIIAEAGVNHNGSLEMAKKLVDVAKESGADAVKFQTFKAENIVSKKAPKADYQVETTGNNETQLQMIQKLELDEEAHA
VLVEYCKKKGIDFLSTPFDIPSVGLLAKKMGVPRLKVPSGEIINAPLLLKVAQTNLPVIVSTGMATLGEIEAALGVLAFG
YLGSKEQPSVRQFQNAFISEEGRRKLSEKVTILHCTTDYPAKLEEVNLNAMLTIKNAFGLPIGYSDHTVGISVAIAAVAM
GATLIEKHFTLDRNLPGPDHRASLEPQELKNMVDGIRAVEKAKGSFVKGPTPAEVLNRAVVRRSLVAKAEIQVNERFSEN
NLDAKRPGTGVSPMLFWEYLSKSSSKAYAVDDLIED

Sequences:

>Translated_356_residues
MTYIIAEAGVNHNGSLEMAKKLVDVAKESGADAVKFQTFKAENIVSKKAPKADYQVETTGNNETQLQMIQKLELDEEAHA
VLVEYCKKKGIDFLSTPFDIPSVGLLAKKMGVPRLKVPSGEIINAPLLLKVAQTNLPVIVSTGMATLGEIEAALGVLAFG
YLGSKEQPSVRQFQNAFISEEGRRKLSEKVTILHCTTDYPAKLEEVNLNAMLTIKNAFGLPIGYSDHTVGISVAIAAVAM
GATLIEKHFTLDRNLPGPDHRASLEPQELKNMVDGIRAVEKAKGSFVKGPTPAEVLNRAVVRRSLVAKAEIQVNERFSEN
NLDAKRPGTGVSPMLFWEYLSKSSSKAYAVDDLIED
>Mature_355_residues
TYIIAEAGVNHNGSLEMAKKLVDVAKESGADAVKFQTFKAENIVSKKAPKADYQVETTGNNETQLQMIQKLELDEEAHAV
LVEYCKKKGIDFLSTPFDIPSVGLLAKKMGVPRLKVPSGEIINAPLLLKVAQTNLPVIVSTGMATLGEIEAALGVLAFGY
LGSKEQPSVRQFQNAFISEEGRRKLSEKVTILHCTTDYPAKLEEVNLNAMLTIKNAFGLPIGYSDHTVGISVAIAAVAMG
ATLIEKHFTLDRNLPGPDHRASLEPQELKNMVDGIRAVEKAKGSFVKGPTPAEVLNRAVVRRSLVAKAEIQVNERFSENN
LDAKRPGTGVSPMLFWEYLSKSSSKAYAVDDLIED

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=311, Percent_Identity=33.7620578778135, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI21357081, Length=275, Percent_Identity=33.4545454545455, Blast_Score=157, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38708; Mature: 38577

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYIIAEAGVNHNGSLEMAKKLVDVAKESGADAVKFQTFKAENIVSKKAPKADYQVETTG
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHCCCCCCEEEEECC
NNETQLQMIQKLELDEEAHAVLVEYCKKKGIDFLSTPFDIPSVGLLAKKMGVPRLKVPSG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCC
EIINAPLLLKVAQTNLPVIVSTGMATLGEIEAALGVLAFGYLGSKEQPSVRQFQNAFISE
CEECCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCH
EGRRKLSEKVTILHCTTDYPAKLEEVNLNAMLTIKNAFGLPIGYSDHTVGISVAIAAVAM
HHHHHHHHCEEEEEECCCCCCCHHEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
GATLIEKHFTLDRNLPGPDHRASLEPQELKNMVDGIRAVEKAKGSFVKGPTPAEVLNRAV
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VRRSLVAKAEIQVNERFSENNLDAKRPGTGVSPMLFWEYLSKSSSKAYAVDDLIED
HHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEHHHHHCC
>Mature Secondary Structure 
TYIIAEAGVNHNGSLEMAKKLVDVAKESGADAVKFQTFKAENIVSKKAPKADYQVETTG
EEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHCCCCCCEEEEECC
NNETQLQMIQKLELDEEAHAVLVEYCKKKGIDFLSTPFDIPSVGLLAKKMGVPRLKVPSG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCC
EIINAPLLLKVAQTNLPVIVSTGMATLGEIEAALGVLAFGYLGSKEQPSVRQFQNAFISE
CEECCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCH
EGRRKLSEKVTILHCTTDYPAKLEEVNLNAMLTIKNAFGLPIGYSDHTVGISVAIAAVAM
HHHHHHHHCEEEEEECCCCCCCHHEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
GATLIEKHFTLDRNLPGPDHRASLEPQELKNMVDGIRAVEKAKGSFVKGPTPAEVLNRAV
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VRRSLVAKAEIQVNERFSENNLDAKRPGTGVSPMLFWEYLSKSSSKAYAVDDLIED
HHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]