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The map label for this gene is arnA [H]

Identifier: 42523179

GI number: 42523179

Start: 1618384

End: 1619271

Strand: Direct

Name: arnA [H]

Synonym: Bd1681

Alternate gene names: 42523179

Gene position: 1618384-1619271 (Clockwise)

Preceding gene: 42523178

Following gene: 42523180

Centisome position: 42.78

GC content: 43.24

Gene sequence:

>888_bases
ATGAAGATTGCGTTTATTGGCTGCGTGGATTTTAGTGAAGCTATGCTCAGAACGGTACTTAACGTTCCAAAAGCTGAAGT
TTGCTGTATTATCACCCGTAAGGCTTCATCATTTAACAGCGACTTTCGAGACCTGACTCCCATTGCTGAAGAAAGGAAGA
TCCCAGTGTTTCATGCGACGGGGAATATGCAGTCGTCCATGGAATCTTTCCTTCAAGAGCACTCTCCAGATGTAATTTTT
TGCTTTGGTTGGTCTTATTTGCTTCAGCCCGCAATATTGAACTTATCACGTTTGGGAGTTGTTGGTTTCCATCCGGCAGA
GCTACCTGAAAATCGCGGACGCCATCCTATTATTTGGGCTTTAGCATTGGGGTTGAAGCAGACAGCTTCAACATTCTTTT
GGATGGATGACGGAGCTGATAGTGGAGATATCCTCAGTCAACAACCTATTCAGATCTCAGACGACGATGATGCAGCCTCT
CTTTATCATAAAGTTATTGAGACAGCTCAGAATCAAGTTGCCGTATTTGTGACTGACTTGCTGGTGGGTAGAGTAATTAG
ACTTCCTCAGGATGCCACTCGGGCAACATATTGGAGAAAACGAGGTAAGTCAGATGGGCGAATTGACTTTAGGATGAGTT
CTTCCGGAATTCATAATTTGGTACGTGCTCTAGCAAGGCCCTATGTAGGTGCCCATGTCGAGAAGGATGGTCAAGACTAC
AAGGTTTGGAAAACTCGATTAAGTTCTGTTGTCTTTCCAGTGAATATTGAGCCGGGCAAAGTTGTGGCTGTGAATGGTTC
AGTTCTTACAATTAAGACTTCAGATTCTGCTATCGATATTCTTGAACATGAATTTACAAATCTACCTACCATAGGGGAAT
ACTTGTAA

Upstream 100 bases:

>100_bases
ATGGCGATGGAAATACGGCTGTTAAGGTTGCTGAAGTCCTTGCCTCTTATGATCTTGACGGAATCATTTTCAAAAAATTT
TATAGTATTGATGGCGTGAA

Downstream 100 bases:

>100_bases
TGTCTAAAAATGTAGTGGTTATTGCGCCTCATCCTGACGATGAGACTCTAGGTTGTGGCGGTACAATTTTGAAGCACATA
AAGTCGGGTGATTCAGTTCA

Product: putative formyltransferase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKIAFIGCVDFSEAMLRTVLNVPKAEVCCIITRKASSFNSDFRDLTPIAEERKIPVFHATGNMQSSMESFLQEHSPDVIF
CFGWSYLLQPAILNLSRLGVVGFHPAELPENRGRHPIIWALALGLKQTASTFFWMDDGADSGDILSQQPIQISDDDDAAS
LYHKVIETAQNQVAVFVTDLLVGRVIRLPQDATRATYWRKRGKSDGRIDFRMSSSGIHNLVRALARPYVGAHVEKDGQDY
KVWKTRLSSVVFPVNIEPGKVVAVNGSVLTIKTSDSAIDILEHEFTNLPTIGEYL

Sequences:

>Translated_295_residues
MKIAFIGCVDFSEAMLRTVLNVPKAEVCCIITRKASSFNSDFRDLTPIAEERKIPVFHATGNMQSSMESFLQEHSPDVIF
CFGWSYLLQPAILNLSRLGVVGFHPAELPENRGRHPIIWALALGLKQTASTFFWMDDGADSGDILSQQPIQISDDDDAAS
LYHKVIETAQNQVAVFVTDLLVGRVIRLPQDATRATYWRKRGKSDGRIDFRMSSSGIHNLVRALARPYVGAHVEKDGQDY
KVWKTRLSSVVFPVNIEPGKVVAVNGSVLTIKTSDSAIDILEHEFTNLPTIGEYL
>Mature_295_residues
MKIAFIGCVDFSEAMLRTVLNVPKAEVCCIITRKASSFNSDFRDLTPIAEERKIPVFHATGNMQSSMESFLQEHSPDVIF
CFGWSYLLQPAILNLSRLGVVGFHPAELPENRGRHPIIWALALGLKQTASTFFWMDDGADSGDILSQQPIQISDDDDAAS
LYHKVIETAQNQVAVFVTDLLVGRVIRLPQDATRATYWRKRGKSDGRIDFRMSSSGIHNLVRALARPYVGAHVEKDGQDY
KVWKTRLSSVVFPVNIEPGKVVAVNGSVLTIKTSDSAIDILEHEFTNLPTIGEYL

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=229, Percent_Identity=28.82096069869, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI238814322, Length=177, Percent_Identity=28.8135593220339, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI1788589, Length=277, Percent_Identity=29.9638989169675, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789683, Length=286, Percent_Identity=28.3216783216783, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI133930964, Length=124, Percent_Identity=29.8387096774194, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24585660, Length=234, Percent_Identity=24.3589743589744, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 32839; Mature: 32839

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAFIGCVDFSEAMLRTVLNVPKAEVCCIITRKASSFNSDFRDLTPIAEERKIPVFHAT
CEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHCCCCHHHCCCCEEEEC
GNMQSSMESFLQEHSPDVIFCFGWSYLLQPAILNLSRLGVVGFHPAELPENRGRHPIIWA
CCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEH
LALGLKQTASTFFWMDDGADSGDILSQQPIQISDDDDAASLYHKVIETAQNQVAVFVTDL
HHHHHHHHCCEEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHH
LVGRVIRLPQDATRATYWRKRGKSDGRIDFRMSSSGIHNLVRALARPYVGAHVEKDGQDY
HHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEECCCCCHH
KVWKTRLSSVVFPVNIEPGKVVAVNGSVLTIKTSDSAIDILEHEFTNLPTIGEYL
HHHHHHHHHEEEEEECCCCEEEEECCCEEEEEECCCHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure
MKIAFIGCVDFSEAMLRTVLNVPKAEVCCIITRKASSFNSDFRDLTPIAEERKIPVFHAT
CEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHCCCCHHHCCCCEEEEC
GNMQSSMESFLQEHSPDVIFCFGWSYLLQPAILNLSRLGVVGFHPAELPENRGRHPIIWA
CCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEH
LALGLKQTASTFFWMDDGADSGDILSQQPIQISDDDDAASLYHKVIETAQNQVAVFVTDL
HHHHHHHHCCEEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHH
LVGRVIRLPQDATRATYWRKRGKSDGRIDFRMSSSGIHNLVRALARPYVGAHVEKDGQDY
HHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEECCCCCHH
KVWKTRLSSVVFPVNIEPGKVVAVNGSVLTIKTSDSAIDILEHEFTNLPTIGEYL
HHHHHHHHHEEEEEECCCCEEEEECCCEEEEEECCCHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA