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The map label for this gene is infC [H]

Identifier: 42523122

GI number: 42523122

Start: 1549747

End: 1550283

Strand: Direct

Name: infC [H]

Synonym: Bd1618

Alternate gene names: 42523122

Gene position: 1549747-1550283 (Clockwise)

Preceding gene: 42523121

Following gene: 42523123

Centisome position: 40.97

GC content: 48.42

Gene sequence:

>537_bases
ATGCTGGGCGTGATGACAGTTCCTGAGGCGTTACGCATTGCTGAAGATAGAGGCCTCGATCTTCTTGAGATTGCTCCAAC
AGCAACTCCTCCCACTTGTAAAATCATGGATTACGGCAAGTGGAAGTACGAGAATAAGAAAAAAGCCACTGCGGCTCGTA
AAAAACAGACTGTTGTGACAATCAAAGAAATCCAGATGCGTCCTCGCACGGATCAGCATGACTTTGAAACCAAGATGAAC
CACGCCCGCCGCTTCCTTCTGGAAGGCGACAAGGTGAAGGTTTCCTTGCGTTTCATGGGTCGTGAAATGGCCCACCAGGA
ATTGGGTATGGACGTGATGAAAAAGTGCATCGCTTTCGTTGATGATCTGGCGCTGGTTGAATCTCAGCCGAAGATGGAAG
GTAAGAACATGTTCCTGATGCTGGGTCCAGACCCGCTCAAGATCAAAGAATACCAGAAACTTCACCCGAACAAGTCCAAG
CAAGACACCAAAGAACTTGCTGAGCTTGAAGAGGTCGAAGAAGACGACGAAGAGTAA

Upstream 100 bases:

>100_bases
CGGTCGCTTTGATCGCAACAAAAAAGACTCTAAAGACTCATTGAGAGTCAACCGCGAGATTCGCGCGCAACAGATCCGTG
TTATCGATGATGAAGGTAAC

Downstream 100 bases:

>100_bases
AAGGTACCTCTGCCGTACCCTCCGCAGGAGGGCCCCCGGCAGTTTTTCCGAAGCGCTGCGTCGAACCAGTAAGCTGATAC
AATTTGTTCAATAAAACCCA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MLGVMTVPEALRIAEDRGLDLLEIAPTATPPTCKIMDYGKWKYENKKKATAARKKQTVVTIKEIQMRPRTDQHDFETKMN
HARRFLLEGDKVKVSLRFMGREMAHQELGMDVMKKCIAFVDDLALVESQPKMEGKNMFLMLGPDPLKIKEYQKLHPNKSK
QDTKELAELEEVEEDDEE

Sequences:

>Translated_178_residues
MLGVMTVPEALRIAEDRGLDLLEIAPTATPPTCKIMDYGKWKYENKKKATAARKKQTVVTIKEIQMRPRTDQHDFETKMN
HARRFLLEGDKVKVSLRFMGREMAHQELGMDVMKKCIAFVDDLALVESQPKMEGKNMFLMLGPDPLKIKEYQKLHPNKSK
QDTKELAELEEVEEDDEE
>Mature_178_residues
MLGVMTVPEALRIAEDRGLDLLEIAPTATPPTCKIMDYGKWKYENKKKATAARKKQTVVTIKEIQMRPRTDQHDFETKMN
HARRFLLEGDKVKVSLRFMGREMAHQELGMDVMKKCIAFVDDLALVESQPKMEGKNMFLMLGPDPLKIKEYQKLHPNKSK
QDTKELAELEEVEEDDEE

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=143, Percent_Identity=50.3496503496504, Blast_Score=143, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20579; Mature: 20579

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGVMTVPEALRIAEDRGLDLLEIAPTATPPTCKIMDYGKWKYENKKKATAARKKQTVVT
CCCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHEEE
IKEIQMRPRTDQHDFETKMNHARRFLLEGDKVKVSLRFMGREMAHQELGMDVMKKCIAFV
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHHH
DDLALVESQPKMEGKNMFLMLGPDPLKIKEYQKLHPNKSKQDTKELAELEEVEEDDEE
HHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLGVMTVPEALRIAEDRGLDLLEIAPTATPPTCKIMDYGKWKYENKKKATAARKKQTVVT
CCCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHEEE
IKEIQMRPRTDQHDFETKMNHARRFLLEGDKVKVSLRFMGREMAHQELGMDVMKKCIAFV
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHHH
DDLALVESQPKMEGKNMFLMLGPDPLKIKEYQKLHPNKSKQDTKELAELEEVEEDDEE
HHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA