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The map label for this gene is pilC [H]

Identifier: 42523018

GI number: 42523018

Start: 1432713

End: 1433930

Strand: Direct

Name: pilC [H]

Synonym: Bd1511

Alternate gene names: 42523018

Gene position: 1432713-1433930 (Clockwise)

Preceding gene: 42523017

Following gene: 42523019

Centisome position: 37.87

GC content: 52.55

Gene sequence:

>1218_bases
ATGGCAAAATTCCAGTATCAGGCCAAGAATGCCTCTGGCCAAATGGTTCAGGGCGAGATCGAAGCCGCTTCCCAGCAGGA
AGCCATCATCCGTCTGCGCGCCCAGCAGCTTCTGCCAGTGCGAGTGGTGGCCTTCGGGGCTTCCCGCGCTTCGGCGGGAA
AAACTCCCAGTTTGTTTGCTCCGACGGTCAAAGGTAAGGATCTGCAGATTTTCACGCGTCAGTTTGCAACTTTGATCAAC
GCCGGTATCCCGGTGGTGGATTCTTTGAAAATCCTGTCTGAAGGTTTGCGTCCGGGTCTTCTGAAAGAGGCCTCGGCCCA
GGTGAAAACGTCGATCGAGGGCGGTCGTCGCCTGGCGGACTCGATGGCGCAGGTGCCAAACGTATTTGATAAGTTGTATG
TGAATATGATCCAGGCCGGGGAAGAAGCCGGTATCCTTGACGGGATTCTGCAGCGTCTGGCCAGTTACATGGAAAAATCC
GAAAAAATCAAGGCCCAGGTGAAAGGCGCCTTGGTGTATCCGATGGTTATCATCGTCGTGGCGATGATCGTGATCGCCGG
TATTTTGGTATTCATCATTCCGAAGTTCATGGAATTCTTCGCTGGTTCCGGTAAAGAGCCACCAATGCTGACCTTGATGG
TGGTGAACTTGAGTAACTCGATGATCAACAACTGGTATCTGTACCTGGGTGTGATGGTGATCGGCCCGATGGCATTGATG
CAGTGGCTGAAAACCGAGGGTGGTAAAGACGCCTTTGACCGTTTTATCATGAAAGCGCCGGTGTTTGGTGAAGTGGTGCA
AAAATCCGCGATCGCGCGTTTGACACGCACATTGTCGACGTTGTTGTCCTCAGGTGTGGGTTTGATCGAGGCGATTGAGA
TTTCGGCGAAGACCGCGGGTAACGTGGTGATTGAGCAGTCCCTGCTTCGCTGTAAAGAGTCCGTCACTGCGGGTCGTACC
TTTGCGTCCCCGCTGGCGAAGGAAAAAGCCTTCCCCGAGATGGTGGTTCAGATGATCTCTATCGGGGAGCAGTCCGGTAC
AATGGATATCATGCTGGGTAAAATTGCGGACTTCTATGAAGATGAAGTTGAAACTGCCGTGAAAGCGATGACCTCATTGC
TGGAGCCATTATTGATGGTTGTTCTGGGTGGTATCATCGCGGTTCTGGTTGTGGCGATGTATCTTCCGATCTTCAACATG
GCGGATGTGGTTCAATAG

Upstream 100 bases:

>100_bases
CAACATCTGATTCGTCGTCGTGTGGACTTGAAAACCGCGTTTGAAGTGTCCCGCGACCCGGACAACCTCGATCAGCTTCT
TAAGAAGGTAGGTATCTAAG

Downstream 100 bases:

>100_bases
ATGCGTTTAAGTTTTGCTTTGCAGAACAGTAAAAATCAGGGGCTGACGGTGGAATTTACCCGCGTCAGCCTTTTTGCGTT
GATTTTGCTGATCAGTGCGG

Product: pilC; type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAKFQYQAKNASGQMVQGEIEAASQQEAIIRLRAQQLLPVRVVAFGASRASAGKTPSLFAPTVKGKDLQIFTRQFATLIN
AGIPVVDSLKILSEGLRPGLLKEASAQVKTSIEGGRRLADSMAQVPNVFDKLYVNMIQAGEEAGILDGILQRLASYMEKS
EKIKAQVKGALVYPMVIIVVAMIVIAGILVFIIPKFMEFFAGSGKEPPMLTLMVVNLSNSMINNWYLYLGVMVIGPMALM
QWLKTEGGKDAFDRFIMKAPVFGEVVQKSAIARLTRTLSTLLSSGVGLIEAIEISAKTAGNVVIEQSLLRCKESVTAGRT
FASPLAKEKAFPEMVVQMISIGEQSGTMDIMLGKIADFYEDEVETAVKAMTSLLEPLLMVVLGGIIAVLVVAMYLPIFNM
ADVVQ

Sequences:

>Translated_405_residues
MAKFQYQAKNASGQMVQGEIEAASQQEAIIRLRAQQLLPVRVVAFGASRASAGKTPSLFAPTVKGKDLQIFTRQFATLIN
AGIPVVDSLKILSEGLRPGLLKEASAQVKTSIEGGRRLADSMAQVPNVFDKLYVNMIQAGEEAGILDGILQRLASYMEKS
EKIKAQVKGALVYPMVIIVVAMIVIAGILVFIIPKFMEFFAGSGKEPPMLTLMVVNLSNSMINNWYLYLGVMVIGPMALM
QWLKTEGGKDAFDRFIMKAPVFGEVVQKSAIARLTRTLSTLLSSGVGLIEAIEISAKTAGNVVIEQSLLRCKESVTAGRT
FASPLAKEKAFPEMVVQMISIGEQSGTMDIMLGKIADFYEDEVETAVKAMTSLLEPLLMVVLGGIIAVLVVAMYLPIFNM
ADVVQ
>Mature_404_residues
AKFQYQAKNASGQMVQGEIEAASQQEAIIRLRAQQLLPVRVVAFGASRASAGKTPSLFAPTVKGKDLQIFTRQFATLINA
GIPVVDSLKILSEGLRPGLLKEASAQVKTSIEGGRRLADSMAQVPNVFDKLYVNMIQAGEEAGILDGILQRLASYMEKSE
KIKAQVKGALVYPMVIIVVAMIVIAGILVFIIPKFMEFFAGSGKEPPMLTLMVVNLSNSMINNWYLYLGVMVIGPMALMQ
WLKTEGGKDAFDRFIMKAPVFGEVVQKSAIARLTRTLSTLLSSGVGLIEAIEISAKTAGNVVIEQSLLRCKESVTAGRTF
ASPLAKEKAFPEMVVQMISIGEQSGTMDIMLGKIADFYEDEVETAVKAMTSLLEPLLMVVLGGIIAVLVVAMYLPIFNMA
DVVQ

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=403, Percent_Identity=28.5359801488834, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1786295, Length=410, Percent_Identity=25.1219512195122, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 43820; Mature: 43688

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKFQYQAKNASGQMVQGEIEAASQQEAIIRLRAQQLLPVRVVAFGASRASAGKTPSLFA
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCCCCCCCCC
PTVKGKDLQIFTRQFATLINAGIPVVDSLKILSEGLRPGLLKEASAQVKTSIEGGRRLAD
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SMAQVPNVFDKLYVNMIQAGEEAGILDGILQRLASYMEKSEKIKAQVKGALVYPMVIIVV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMIVIAGILVFIIPKFMEFFAGSGKEPPMLTLMVVNLSNSMINNWYLYLGVMVIGPMALM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
QWLKTEGGKDAFDRFIMKAPVFGEVVQKSAIARLTRTLSTLLSSGVGLIEAIEISAKTAG
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
NVVIEQSLLRCKESVTAGRTFASPLAKEKAFPEMVVQMISIGEQSGTMDIMLGKIADFYE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DEVETAVKAMTSLLEPLLMVVLGGIIAVLVVAMYLPIFNMADVVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]