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The map label for this gene is glnS [H]

Identifier: 42522890

GI number: 42522890

Start: 1295672

End: 1297366

Strand: Direct

Name: glnS [H]

Synonym: Bd1371

Alternate gene names: 42522890

Gene position: 1295672-1297366 (Clockwise)

Preceding gene: 42522889

Following gene: 42522891

Centisome position: 34.25

GC content: 50.74

Gene sequence:

>1695_bases
GTGTACTGGTACGCTATGAGCAAGCCCAATAAAACACCTGTAGATGCACCCAATTTCCTGAAACAAATCATCGAAAAAGA
CCTGGAGACTGGCAAAGTCAAAGGCGAAGTGGTCACGCGCTTCCCGCCAGAGCCGAACGGATACCTGCACTTGGGTCACG
CCAAGTCGATCTGTTTGAATTTTGGTCTGGCTCAGGAATACCAGGGTCGCTGCCATCTGCGTTTTGACGACACCAATCCT
GAAACGGAAGAAACCGAATACGTTGAATCCATCCAGGAAGACGTCAAGTGGCTGGGCTATGACTGGGGCCAACACCTGTA
TTACGCGTCTGATTACTTCGAGCAGATCTATCAGTGGGCTGAACAGCTGATTAAAGACGGCAAGGCCTATGTGGATTCCC
AGAATGAAGAGGAAGTGCGCAAGAACCGCGGCGACTTCACGACTCCGGGTAAGGATTCCCCTTACCGCAATCGTACTGTT
GAAGAAAATCTGGATTTGTTCCGTCGCATGCGTGCCGGTGAGTTCGATGAAGGTCAGCATATTCTGCGTGCGAAAATCGA
CATGCAGTCTCCGAACATGAACATGCGTGACCCGTTGTTGTACCGTATCCGCAAGGCGCATCACCACCGTACTGGTGACA
AGTGGTGCATCTATCCGATGTACGATTATGCTCACCCCTTGTCTGATGCAATGGAGCACATCACGCATTCCATCTGTACT
TTGGAATTCCAGGATCACCGTCCATTCTATGACTGGTGTGTGCAGAATGTTCCGGTGCCGGCAGAGCCTCATCAATATGA
GTTTGCACGCATGAACATGACGTATCTGGTGATGAGCAAGCGCAAGCTTTTGCAACTGGTAAAAGAAAAGCTGGTTTCTG
GCTGGGATGACCCGCGCATGCCGACTATTTCCGGTGTTCGCCGTCGTGGTTACACTCCGGAATCCATCCGTCGATTTGCA
AAACGCATTGGTGTGGCGAAATCTGAAAGCATCATCGAATACGACATCCTGGAAAGCTGCGTGCGTGAGCACCTGGATGA
AACGGCTCATCGTGCGATGGCGGTTCTGGATCCAATCAAAGTTGTGATTGAAAACCTGCCGGACGGTCATAAAGAGCTGA
TTGAAACGTCTGTGCATCCAAAAAACACCGAGTTGGGGAACCGCTCTTTGCCGTTCACTAAAGAAGTGTACATTGATGCG
GCGGACTTCATGGAAAATCCGCCGGATGATTACTTCCGTCTGTCTCCGGGCAAGGAAGTTCGTCTGCGCAATGCCTATGT
GATCAAGTGCAAAGACGTGGTCAAAGATGCTTCCGGCAAAGTGACTGAATTGCGCTGTGAATATGATCCTGTGACTTTGG
GCGGTAAGCCGACTGCCGATGGCCGCAAAGTAAAAGGTATCGTCCACTGGGTTTCGGCAACGGATTGTGTGGATGCGGAA
GTGCGTGTGTACGGGCGTCTGTTCAAAGTGGCGGATCCGGAAAATGTACCGGACGGTCAGGATTTCAAAGTGAACCTGAA
TCCGGACTCTTTGAAGGTGATCAAGAACGCGAAGCTGGAAAAAGGTTTGAAGGATGCGAAACTTGAAAACCGTTACCAGT
TTGAACGTGTGGGTTACTTCTGCCTGGACAGTAAGGACTCCAAGCCAGGGGCGTTGGTGTTCAACCGGGTTGTCGAGCTG
CCATCAAGTCACTAA

Upstream 100 bases:

>100_bases
GCTAACTGCGCCTTAGCTTATGCAGGGCAGCAGGAGGGCTTTCGGGCCTAACCAGAGCCAGTTAAGACCCTCCCAGACTT
GACAGAAATCAGGTCGAGGA

Downstream 100 bases:

>100_bases
GAAATTGAAAATTCAAACGACGAAGGCAGCCCCGAGCTGCCTTTGTTTTATAGGTGGTCGCTATGTTGTTTGCTGAAAGT
GTTTATAAGACCCGTCAGGG

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MYWYAMSKPNKTPVDAPNFLKQIIEKDLETGKVKGEVVTRFPPEPNGYLHLGHAKSICLNFGLAQEYQGRCHLRFDDTNP
ETEETEYVESIQEDVKWLGYDWGQHLYYASDYFEQIYQWAEQLIKDGKAYVDSQNEEEVRKNRGDFTTPGKDSPYRNRTV
EENLDLFRRMRAGEFDEGQHILRAKIDMQSPNMNMRDPLLYRIRKAHHHRTGDKWCIYPMYDYAHPLSDAMEHITHSICT
LEFQDHRPFYDWCVQNVPVPAEPHQYEFARMNMTYLVMSKRKLLQLVKEKLVSGWDDPRMPTISGVRRRGYTPESIRRFA
KRIGVAKSESIIEYDILESCVREHLDETAHRAMAVLDPIKVVIENLPDGHKELIETSVHPKNTELGNRSLPFTKEVYIDA
ADFMENPPDDYFRLSPGKEVRLRNAYVIKCKDVVKDASGKVTELRCEYDPVTLGGKPTADGRKVKGIVHWVSATDCVDAE
VRVYGRLFKVADPENVPDGQDFKVNLNPDSLKVIKNAKLEKGLKDAKLENRYQFERVGYFCLDSKDSKPGALVFNRVVEL
PSSH

Sequences:

>Translated_564_residues
MYWYAMSKPNKTPVDAPNFLKQIIEKDLETGKVKGEVVTRFPPEPNGYLHLGHAKSICLNFGLAQEYQGRCHLRFDDTNP
ETEETEYVESIQEDVKWLGYDWGQHLYYASDYFEQIYQWAEQLIKDGKAYVDSQNEEEVRKNRGDFTTPGKDSPYRNRTV
EENLDLFRRMRAGEFDEGQHILRAKIDMQSPNMNMRDPLLYRIRKAHHHRTGDKWCIYPMYDYAHPLSDAMEHITHSICT
LEFQDHRPFYDWCVQNVPVPAEPHQYEFARMNMTYLVMSKRKLLQLVKEKLVSGWDDPRMPTISGVRRRGYTPESIRRFA
KRIGVAKSESIIEYDILESCVREHLDETAHRAMAVLDPIKVVIENLPDGHKELIETSVHPKNTELGNRSLPFTKEVYIDA
ADFMENPPDDYFRLSPGKEVRLRNAYVIKCKDVVKDASGKVTELRCEYDPVTLGGKPTADGRKVKGIVHWVSATDCVDAE
VRVYGRLFKVADPENVPDGQDFKVNLNPDSLKVIKNAKLEKGLKDAKLENRYQFERVGYFCLDSKDSKPGALVFNRVVEL
PSSH
>Mature_564_residues
MYWYAMSKPNKTPVDAPNFLKQIIEKDLETGKVKGEVVTRFPPEPNGYLHLGHAKSICLNFGLAQEYQGRCHLRFDDTNP
ETEETEYVESIQEDVKWLGYDWGQHLYYASDYFEQIYQWAEQLIKDGKAYVDSQNEEEVRKNRGDFTTPGKDSPYRNRTV
EENLDLFRRMRAGEFDEGQHILRAKIDMQSPNMNMRDPLLYRIRKAHHHRTGDKWCIYPMYDYAHPLSDAMEHITHSICT
LEFQDHRPFYDWCVQNVPVPAEPHQYEFARMNMTYLVMSKRKLLQLVKEKLVSGWDDPRMPTISGVRRRGYTPESIRRFA
KRIGVAKSESIIEYDILESCVREHLDETAHRAMAVLDPIKVVIENLPDGHKELIETSVHPKNTELGNRSLPFTKEVYIDA
ADFMENPPDDYFRLSPGKEVRLRNAYVIKCKDVVKDASGKVTELRCEYDPVTLGGKPTADGRKVKGIVHWVSATDCVDAE
VRVYGRLFKVADPENVPDGQDFKVNLNPDSLKVIKNAKLEKGLKDAKLENRYQFERVGYFCLDSKDSKPGALVFNRVVEL
PSSH

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=547, Percent_Identity=46.2522851919561, Blast_Score=444, Evalue=1e-125,
Organism=Homo sapiens, GI62241042, Length=527, Percent_Identity=35.4838709677419, Blast_Score=289, Evalue=5e-78,
Organism=Escherichia coli, GI1786895, Length=555, Percent_Identity=58.1981981981982, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=123, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17543332, Length=538, Percent_Identity=42.3791821561338, Blast_Score=426, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17511007, Length=376, Percent_Identity=38.563829787234, Blast_Score=258, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6324742, Length=593, Percent_Identity=41.9898819561551, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6321192, Length=535, Percent_Identity=37.0093457943925, Blast_Score=316, Evalue=5e-87,
Organism=Drosophila melanogaster, GI17864488, Length=535, Percent_Identity=42.6168224299065, Blast_Score=418, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24649466, Length=414, Percent_Identity=37.9227053140097, Blast_Score=271, Evalue=1e-72,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 65383; Mature: 65383

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWYAMSKPNKTPVDAPNFLKQIIEKDLETGKVKGEVVTRFPPEPNGYLHLGHAKSICLN
CEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHHHHHH
FGLAQEYQGRCHLRFDDTNPETEETEYVESIQEDVKWLGYDWGQHLYYASDYFEQIYQWA
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EQLIKDGKAYVDSQNEEEVRKNRGDFTTPGKDSPYRNRTVEENLDLFRRMRAGEFDEGQH
HHHHHCCHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCE
ILRAKIDMQSPNMNMRDPLLYRIRKAHHHRTGDKWCIYPMYDYAHPLSDAMEHITHSICT
EEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECHHHCCCHHHHHHHHHHHHEE
LEFQDHRPFYDWCVQNVPVPAEPHQYEFARMNMTYLVMSKRKLLQLVKEKLVSGWDDPRM
EEECCCCCHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PTISGVRRRGYTPESIRRFAKRIGVAKSESIIEYDILESCVREHLDETAHRAMAVLDPIK
CCHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVIENLPDGHKELIETSVHPKNTELGNRSLPFTKEVYIDAADFMENPPDDYFRLSPGKEV
HHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHEEEHHHHHCCCCCCCEECCCCCCE
RLRNAYVIKCKDVVKDASGKVTELRCEYDPVTLGGKPTADGRKVKGIVHWVSATDCVDAE
EECCEEEEEEHHHHHCCCCCEEEEEECCCCEEECCCCCCCCCCEEHEEEEECCCCCCCHH
VRVYGRLFKVADPENVPDGQDFKVNLNPDSLKVIKNAKLEKGLKDAKLENRYQFERVGYF
HHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEE
CLDSKDSKPGALVFNRVVELPSSH
EECCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYWYAMSKPNKTPVDAPNFLKQIIEKDLETGKVKGEVVTRFPPEPNGYLHLGHAKSICLN
CEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHHHHHH
FGLAQEYQGRCHLRFDDTNPETEETEYVESIQEDVKWLGYDWGQHLYYASDYFEQIYQWA
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EQLIKDGKAYVDSQNEEEVRKNRGDFTTPGKDSPYRNRTVEENLDLFRRMRAGEFDEGQH
HHHHHCCHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCE
ILRAKIDMQSPNMNMRDPLLYRIRKAHHHRTGDKWCIYPMYDYAHPLSDAMEHITHSICT
EEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECHHHCCCHHHHHHHHHHHHEE
LEFQDHRPFYDWCVQNVPVPAEPHQYEFARMNMTYLVMSKRKLLQLVKEKLVSGWDDPRM
EEECCCCCHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PTISGVRRRGYTPESIRRFAKRIGVAKSESIIEYDILESCVREHLDETAHRAMAVLDPIK
CCHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVIENLPDGHKELIETSVHPKNTELGNRSLPFTKEVYIDAADFMENPPDDYFRLSPGKEV
HHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHEEEHHHHHCCCCCCCEECCCCCCE
RLRNAYVIKCKDVVKDASGKVTELRCEYDPVTLGGKPTADGRKVKGIVHWVSATDCVDAE
EECCEEEEEEHHHHHCCCCCEEEEEECCCCEEECCCCCCCCCCEEHEEEEECCCCCCCHH
VRVYGRLFKVADPENVPDGQDFKVNLNPDSLKVIKNAKLEKGLKDAKLENRYQFERVGYF
HHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEE
CLDSKDSKPGALVFNRVVELPSSH
EECCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA