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The map label for this gene is 42522725

Identifier: 42522725

GI number: 42522725

Start: 1128086

End: 1129651

Strand: Direct

Name: 42522725

Synonym: Bd1188

Alternate gene names: NA

Gene position: 1128086-1129651 (Clockwise)

Preceding gene: 42522724

Following gene: 42522726

Centisome position: 29.82

GC content: 51.02

Gene sequence:

>1566_bases
ATGGAGATCGTAATCAGCGCCATTATCGGCCTGCTCATCGGTGGAACAGTCGTCTTCGTTATTAAACGTCTGCAGGACAA
CAACAAAAAGAAATCTGCACGTTTCGAAGCAGAACGCATCGTCAACAAAGCCAACTCGGAAGCGGCTAAAATCAAAAAAG
AGTCCGAAAACAAAGCCAAGGATTTCGAATCCCGCGCCCGCAAGAATGTCGAGCAGGACATTCACAAACAAAAATCCACT
TTGAAAAACAAAGAGTCCCAGCTGGAGCGCCGTTTGAAAGAGGTCGAAGACCAGTTCAAACAAAAGATGGAAGAAAACGA
GCGCTATCTGAACTCTTTGAAAGACCGCGAGGAAAAAATCGCGATCTCTGAAAACCGCATCAAAGATCTTGAGAAAAAAG
GCGAGGCTCACATTGGGGAGCTGAAGCAAAAGCTTGAGTCCGTAGCCGCCATGAGCCAGGACGAAGCGCGCCGCCAGTTG
CTGACAGCTTTGGAAGACGAAGCGAAACAGGAAGCAGCGAAGAAAATCGCCCAGATCGAAGAAGAAGCAAACAAAGAATC
CGAGAAAAAAGCCAAGCGCATTCTGGCAACAGCTTTGTCCCGCTTTGCTTCCGAGTACACGTCTGAAAGAACTGTCAGCG
TTCTGGCTCTGCCAAACGACGAGATGAAGGGTAAAATCATCGGCCGTGAAGGTCGTAACATCCGCACGTTGGAAGCCCAC
TGCGGTGTGGATCTGATCGTTGATGACACGCCAGAAGCAGTTGTGATTTCCGGTTTCGATCCGGTTCGCCGTGAACTGGC
TCGTCGTACCATCGAAAAGCTGATGGAAGACGGTCGTGTTCACCCGGCACGTATCGAAGAAGTTGCCGAAAAGCAGCGCA
ACGAACTGATGAAATCCATGAAAGAGGAAGGCGAGCGCCACGTGATGGAGCTGGGCATTCCGAACATGCACCCTGAACTG
GTGAAAATCATCGGTGGTTTGAAATACCGTTCTTACCAGGGGCAAAATGCCTTGAATCAGTCTTTGGAAGTGGCGACGAT
TGCCGGTCTTCTGGCGGCTGAACTGGGTGTCAGCGTGAAGCTGGCTCGCCGTGCAGGTCTTTTGCACAATATCGGTAAAG
CGATCGATCACACCGTGGAAGGCAGCTATGCTTTCGTGGGTGCTGAAGCCGCTAAGAAATACAATGAATCCGAAGATGTT
TGTCATGCGATCCGCGCCCACGATGAAGAGGAAAAACCTCACTCCATCCTGGCTTGGATTGTTCATGCAGCTTACACTCT
TTCCAGCTCTCGTCCGGGCGCACGTCGTCCACAGATGGATACCTTCATCCATCGTTTGGAAGACCTGGAAAGCATCGGCA
ACAGCTTCGACGGCGTTTTGAAAACATTGGCCCTGCAAGCCGGTAAAGACATCCGCGTGTTGGTTGAATCCAGCCGTGTG
ACCGATGATCAGGCCGTGATGTTGTCCCGTGATATCGCTCGTAAGATCGAACGCGAGATGCCTCAGGCCGGTCAGGTGAA
AGTCACTGTGGTTCGTGAAACCCGTTCTGTGGAGCATGCAAGATGA

Upstream 100 bases:

>100_bases
GCCGATCCGCTTCCCACCGAGCCTCATGATGTGAAAATGGATTTCCTCATCACAGAATCAGGACTGGTCGATTGCAAGAA
GCATCAGGAGTAAATGAATC

Downstream 100 bases:

>100_bases
TGAGTCCTCAGGAGCAGCTGGAAAGAATCAAATTCGGCACGGCCGACTTCATCAATGACGAGGACATGCTTAAAAAACTT
AAGCGCTCGATCGAGACGAA

Product: HD superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MEIVISAIIGLLIGGTVVFVIKRLQDNNKKKSARFEAERIVNKANSEAAKIKKESENKAKDFESRARKNVEQDIHKQKST
LKNKESQLERRLKEVEDQFKQKMEENERYLNSLKDREEKIAISENRIKDLEKKGEAHIGELKQKLESVAAMSQDEARRQL
LTALEDEAKQEAAKKIAQIEEEANKESEKKAKRILATALSRFASEYTSERTVSVLALPNDEMKGKIIGREGRNIRTLEAH
CGVDLIVDDTPEAVVISGFDPVRRELARRTIEKLMEDGRVHPARIEEVAEKQRNELMKSMKEEGERHVMELGIPNMHPEL
VKIIGGLKYRSYQGQNALNQSLEVATIAGLLAAELGVSVKLARRAGLLHNIGKAIDHTVEGSYAFVGAEAAKKYNESEDV
CHAIRAHDEEEKPHSILAWIVHAAYTLSSSRPGARRPQMDTFIHRLEDLESIGNSFDGVLKTLALQAGKDIRVLVESSRV
TDDQAVMLSRDIARKIEREMPQAGQVKVTVVRETRSVEHAR

Sequences:

>Translated_521_residues
MEIVISAIIGLLIGGTVVFVIKRLQDNNKKKSARFEAERIVNKANSEAAKIKKESENKAKDFESRARKNVEQDIHKQKST
LKNKESQLERRLKEVEDQFKQKMEENERYLNSLKDREEKIAISENRIKDLEKKGEAHIGELKQKLESVAAMSQDEARRQL
LTALEDEAKQEAAKKIAQIEEEANKESEKKAKRILATALSRFASEYTSERTVSVLALPNDEMKGKIIGREGRNIRTLEAH
CGVDLIVDDTPEAVVISGFDPVRRELARRTIEKLMEDGRVHPARIEEVAEKQRNELMKSMKEEGERHVMELGIPNMHPEL
VKIIGGLKYRSYQGQNALNQSLEVATIAGLLAAELGVSVKLARRAGLLHNIGKAIDHTVEGSYAFVGAEAAKKYNESEDV
CHAIRAHDEEEKPHSILAWIVHAAYTLSSSRPGARRPQMDTFIHRLEDLESIGNSFDGVLKTLALQAGKDIRVLVESSRV
TDDQAVMLSRDIARKIEREMPQAGQVKVTVVRETRSVEHAR
>Mature_521_residues
MEIVISAIIGLLIGGTVVFVIKRLQDNNKKKSARFEAERIVNKANSEAAKIKKESENKAKDFESRARKNVEQDIHKQKST
LKNKESQLERRLKEVEDQFKQKMEENERYLNSLKDREEKIAISENRIKDLEKKGEAHIGELKQKLESVAAMSQDEARRQL
LTALEDEAKQEAAKKIAQIEEEANKESEKKAKRILATALSRFASEYTSERTVSVLALPNDEMKGKIIGREGRNIRTLEAH
CGVDLIVDDTPEAVVISGFDPVRRELARRTIEKLMEDGRVHPARIEEVAEKQRNELMKSMKEEGERHVMELGIPNMHPEL
VKIIGGLKYRSYQGQNALNQSLEVATIAGLLAAELGVSVKLARRAGLLHNIGKAIDHTVEGSYAFVGAEAAKKYNESEDV
CHAIRAHDEEEKPHSILAWIVHAAYTLSSSRPGARRPQMDTFIHRLEDLESIGNSFDGVLKTLALQAGKDIRVLVESSRV
TDDQAVMLSRDIARKIEREMPQAGQVKVTVVRETRSVEHAR

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD1_BDEBA (Q6MNQ3)

Other databases:

- EMBL:   BX842649
- RefSeq:   NP_968105.1
- ProteinModelPortal:   Q6MNQ3
- SMR:   Q6MNQ3
- GeneID:   2733226
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd1188
- NMPDR:   fig|264462.1.peg.1075
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- BioCyc:   BBAC264462:BD1188-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 58705; Mature: 58705

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe1b1ae0)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIVISAIIGLLIGGTVVFVIKRLQDNNKKKSARFEAERIVNKANSEAAKIKKESENKAK
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DFESRARKNVEQDIHKQKSTLKNKESQLERRLKEVEDQFKQKMEENERYLNSLKDREEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISENRIKDLEKKGEAHIGELKQKLESVAAMSQDEARRQLLTALEDEAKQEAAKKIAQIE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEANKESEKKAKRILATALSRFASEYTSERTVSVLALPNDEMKGKIIGREGRNIRTLEAH
HHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEECCCCCCEEEEEHH
CGVDLIVDDTPEAVVISGFDPVRRELARRTIEKLMEDGRVHPARIEEVAEKQRNELMKSM
CCEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KEEGERHVMELGIPNMHPELVKIIGGLKYRSYQGQNALNQSLEVATIAGLLAAELGVSVK
HHHHHHHHHHHCCCCCCHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
LARRAGLLHNIGKAIDHTVEGSYAFVGAEAAKKYNESEDVCHAIRAHDEEEKPHSILAWI
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
VHAAYTLSSSRPGARRPQMDTFIHRLEDLESIGNSFDGVLKTLALQAGKDIRVLVESSRV
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
TDDQAVMLSRDIARKIEREMPQAGQVKVTVVRETRSVEHAR
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHCCCCH
>Mature Secondary Structure
MEIVISAIIGLLIGGTVVFVIKRLQDNNKKKSARFEAERIVNKANSEAAKIKKESENKAK
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DFESRARKNVEQDIHKQKSTLKNKESQLERRLKEVEDQFKQKMEENERYLNSLKDREEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISENRIKDLEKKGEAHIGELKQKLESVAAMSQDEARRQLLTALEDEAKQEAAKKIAQIE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEANKESEKKAKRILATALSRFASEYTSERTVSVLALPNDEMKGKIIGREGRNIRTLEAH
HHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEECCCCCCEEEEEHH
CGVDLIVDDTPEAVVISGFDPVRRELARRTIEKLMEDGRVHPARIEEVAEKQRNELMKSM
CCEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KEEGERHVMELGIPNMHPELVKIIGGLKYRSYQGQNALNQSLEVATIAGLLAAELGVSVK
HHHHHHHHHHHCCCCCCHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
LARRAGLLHNIGKAIDHTVEGSYAFVGAEAAKKYNESEDVCHAIRAHDEEEKPHSILAWI
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
VHAAYTLSSSRPGARRPQMDTFIHRLEDLESIGNSFDGVLKTLALQAGKDIRVLVESSRV
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
TDDQAVMLSRDIARKIEREMPQAGQVKVTVVRETRSVEHAR
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA