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The map label for this gene is mtnN [H]

Identifier: 42522418

GI number: 42522418

Start: 793550

End: 794113

Strand: Direct

Name: mtnN [H]

Synonym: Bd0846

Alternate gene names: 42522418

Gene position: 793550-794113 (Clockwise)

Preceding gene: 42522417

Following gene: 42522419

Centisome position: 20.98

GC content: 50.35

Gene sequence:

>564_bases
GTGGCTTTGGTGATGGCGCTTCCGGGCGAGTCTCAGGGCTTCTTTGAAAAAGAAAATATCCCTGTGGTCTATACCGGCAT
TGGCAAAGTGAATGCCGCGCTGGTGGCTATGGATGTGATTCATAAAACCAAGTGCAAAGTCATGATCAACCTGGGAACCG
CGGGCAGTTCCCGTTTTAAAACCCATGACCTTGTCGAGGTTTCAAGCTTCGTGCAAAGAGACATGGACATTTCCCCTTTG
GGATTCAAGGTCGGTGAAACACCGTTTGATCCGCTTCCAGGAGCGATTGACCTGATTCCTTACTTCCCGGAGCTGTCTCA
TGGGGTGTGTGGCACAGGGGACAGCTTTGAAACCGGCACTCCAAAAGTGCCTTGCGAGCTGGTGGACATGGAAGGTTATG
CCCTGGCCAAGGTTTGTCGCAAAATGAACGTGCAGCTGATCTCACTGAAGTACATCACCGACGGGGCGGATCACAATGCC
CACAATGATTGGGAGGCCAATCTGGTTCATGGGGCTAAAAAGCTTCTGGAATTTTATAAAAAAATGGTGACCATCCCAAG
TTAG

Upstream 100 bases:

>100_bases
TACTCCGTGGAGTCAGTGGCAGTTCTGGTCAATCTGACGTTCCTTAACAAGATGACCTACAACGATCAAAAGGTGGCTTC
GCTTGTTCAATATTAATGAC

Downstream 100 bases:

>100_bases
AATTGAGCGGGCTCCGACAGGGGCCCGTCTCTTTTTGGAACATGGAAAAACCTCATCTTTGGTCCGGGATTGCCGATAAG
TTTTCCATGATCAAGCCAGC

Product: putative MTA/SAH nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MALVMALPGESQGFFEKENIPVVYTGIGKVNAALVAMDVIHKTKCKVMINLGTAGSSRFKTHDLVEVSSFVQRDMDISPL
GFKVGETPFDPLPGAIDLIPYFPELSHGVCGTGDSFETGTPKVPCELVDMEGYALAKVCRKMNVQLISLKYITDGADHNA
HNDWEANLVHGAKKLLEFYKKMVTIPS

Sequences:

>Translated_187_residues
MALVMALPGESQGFFEKENIPVVYTGIGKVNAALVAMDVIHKTKCKVMINLGTAGSSRFKTHDLVEVSSFVQRDMDISPL
GFKVGETPFDPLPGAIDLIPYFPELSHGVCGTGDSFETGTPKVPCELVDMEGYALAKVCRKMNVQLISLKYITDGADHNA
HNDWEANLVHGAKKLLEFYKKMVTIPS
>Mature_186_residues
ALVMALPGESQGFFEKENIPVVYTGIGKVNAALVAMDVIHKTKCKVMINLGTAGSSRFKTHDLVEVSSFVQRDMDISPLG
FKVGETPFDPLPGAIDLIPYFPELSHGVCGTGDSFETGTPKVPCELVDMEGYALAKVCRKMNVQLISLKYITDGADHNAH
NDWEANLVHGAKKLLEFYKKMVTIPS

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 20404; Mature: 20273

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVMALPGESQGFFEKENIPVVYTGIGKVNAALVAMDVIHKTKCKVMINLGTAGSSRFK
CEEEEECCCCCCCCEECCCCCEEEECCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCC
THDLVEVSSFVQRDMDISPLGFKVGETPFDPLPGAIDLIPYFPELSHGVCGTGDSFETGT
HHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
PKVPCELVDMEGYALAKVCRKMNVQLISLKYITDGADHNAHNDWEANLVHGAKKLLEFYK
CCCCEEEEECCCHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
KMVTIPS
HHHCCCC
>Mature Secondary Structure 
ALVMALPGESQGFFEKENIPVVYTGIGKVNAALVAMDVIHKTKCKVMINLGTAGSSRFK
EEEEECCCCCCCCEECCCCCEEEECCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCC
THDLVEVSSFVQRDMDISPLGFKVGETPFDPLPGAIDLIPYFPELSHGVCGTGDSFETGT
HHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
PKVPCELVDMEGYALAKVCRKMNVQLISLKYITDGADHNAHNDWEANLVHGAKKLLEFYK
CCCCEEEEECCCHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
KMVTIPS
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA