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The map label for this gene is msrB [H]

Identifier: 42522340

GI number: 42522340

Start: 719145

End: 719561

Strand: Direct

Name: msrB [H]

Synonym: Bd0757

Alternate gene names: 42522340

Gene position: 719145-719561 (Clockwise)

Preceding gene: 42522329

Following gene: 42522341

Centisome position: 19.01

GC content: 52.28

Gene sequence:

>417_bases
ATGGCTGACAAGGTTTTAAAATGCGGGCTGCCCTCGGATGAAGGGGAGCTTAAAAAGATTCTGACCCCTGAACAATATCG
CATCATGGTTGAAAACGGCACTGAGCGTCCGTTCCAGAATGCCTATTGGAATCATCATGAACAGGGCATCTATGTGGATG
CTATTTCCGGTGTGCCGCTTTTTTCCAGCGATGACAAATTTGATTCCGGCTCCGGCTGGCCCAGCTTCACCCGCCCCATC
TCTGCGGATGCGGTGAAAGAGATTGCGGATTATTCCCACGGGATGACGCGGATTGAAGTGCGGGCCTCTTCGTCGAATTC
TCACTTGGGGCATGTGTTTGATGACGGGCCGGCGCCCACGGGTCTTCGTTATTGCATCAATTCGGCCTCGTTGAAATTCA
TTCCGCGCAAAGGTTGA

Upstream 100 bases:

>100_bases
AAAACTTCTTCATTCCCCCATACTAGCAAGGTTGAGTGGCGAACGACATGAATTCGGCCACACTCTGGACTAAAGCTCCT
GGACCGGGTACAACCAAGGT

Downstream 100 bases:

>100_bases
GTCCTGAGCAGACCTCAGCATTTAATCCCGCAAAAACACAGAAAATAGTCCATACTGGTGGAATGAAACTCATCGGTTCT
GTTATTGCTTTCATGTTGTT

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MADKVLKCGLPSDEGELKKILTPEQYRIMVENGTERPFQNAYWNHHEQGIYVDAISGVPLFSSDDKFDSGSGWPSFTRPI
SADAVKEIADYSHGMTRIEVRASSSNSHLGHVFDDGPAPTGLRYCINSASLKFIPRKG

Sequences:

>Translated_138_residues
MADKVLKCGLPSDEGELKKILTPEQYRIMVENGTERPFQNAYWNHHEQGIYVDAISGVPLFSSDDKFDSGSGWPSFTRPI
SADAVKEIADYSHGMTRIEVRASSSNSHLGHVFDDGPAPTGLRYCINSASLKFIPRKG
>Mature_137_residues
ADKVLKCGLPSDEGELKKILTPEQYRIMVENGTERPFQNAYWNHHEQGIYVDAISGVPLFSSDDKFDSGSGWPSFTRPIS
ADAVKEIADYSHGMTRIEVRASSSNSHLGHVFDDGPAPTGLRYCINSASLKFIPRKG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=141, Percent_Identity=49.645390070922, Blast_Score=145, Evalue=7e-36,
Organism=Homo sapiens, GI301336162, Length=141, Percent_Identity=49.645390070922, Blast_Score=145, Evalue=7e-36,
Organism=Homo sapiens, GI73089054, Length=141, Percent_Identity=49.645390070922, Blast_Score=145, Evalue=7e-36,
Organism=Homo sapiens, GI37620216, Length=128, Percent_Identity=51.5625, Blast_Score=144, Evalue=2e-35,
Organism=Homo sapiens, GI117606353, Length=143, Percent_Identity=44.7552447552448, Blast_Score=122, Evalue=7e-29,
Organism=Homo sapiens, GI7706511, Length=96, Percent_Identity=40.625, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788077, Length=123, Percent_Identity=51.219512195122, Blast_Score=132, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17553450, Length=122, Percent_Identity=47.5409836065574, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI115532676, Length=120, Percent_Identity=48.3333333333333, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319816, Length=128, Percent_Identity=35.9375, Blast_Score=82, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221378664, Length=123, Percent_Identity=48.780487804878, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45553335, Length=123, Percent_Identity=47.9674796747967, Blast_Score=122, Evalue=5e-29,
Organism=Drosophila melanogaster, GI21356369, Length=123, Percent_Identity=47.9674796747967, Blast_Score=122, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24645799, Length=123, Percent_Identity=47.9674796747967, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI221378662, Length=130, Percent_Identity=46.1538461538462, Blast_Score=122, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24645804, Length=134, Percent_Identity=44.0298507462687, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24645801, Length=134, Percent_Identity=44.0298507462687, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15260; Mature: 15129

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKVLKCGLPSDEGELKKILTPEQYRIMVENGTERPFQNAYWNHHEQGIYVDAISGVPL
CCCCEEECCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCC
FSSDDKFDSGSGWPSFTRPISADAVKEIADYSHGMTRIEVRASSSNSHLGHVFDDGPAPT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCCCC
GLRYCINSASLKFIPRKG
HHHHHHCCCCEEEEECCC
>Mature Secondary Structure 
ADKVLKCGLPSDEGELKKILTPEQYRIMVENGTERPFQNAYWNHHEQGIYVDAISGVPL
CCCEEECCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCC
FSSDDKFDSGSGWPSFTRPISADAVKEIADYSHGMTRIEVRASSSNSHLGHVFDDGPAPT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCCCC
GLRYCINSASLKFIPRKG
HHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA