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The map label for this gene is 42522064

Identifier: 42522064

GI number: 42522064

Start: 427304

End: 427732

Strand: Direct

Name: 42522064

Synonym: Bd0456

Alternate gene names: NA

Gene position: 427304-427732 (Clockwise)

Preceding gene: 42522063

Following gene: 42522065

Centisome position: 11.3

GC content: 53.15

Gene sequence:

>429_bases
ATGGAAACAAATGAACTGCATCGAGGGCGTCTGATTGATCACTTGCAGCTGGTGGTGAAGGATTTGGATAAAACGAAAAG
GTTTTATTCTGCGGTTTTTGAGACTCTGGGCATTCCGATGGGTGGTGAAGGCCCTGGATTTTTCTGGTGTGATGAGTTGT
TTATTTCCTCTGCCGACAGTCCGGCCAGCGCAGGCAAGCTGACTGGCAGAACGCATCTGGCGTTTCAGGCCAAGGATCGC
GACATGGTGAAAAAGTTCTACGAAGTGGCGCTGCAATCCGGCGGCCAGGATAACGGTGCGCCGGGCGAGCGTCCTTACCA
CCCGGGTTATTATGCGGCCTTTGTGCTGGATCCAGACGGAAACAACATCGAAGCGGTCTTCCATGGTCCGGCGAAAAAGT
CGGCGGAGTCGGTGAAGATCACCTTCTAA

Upstream 100 bases:

>100_bases
CTTTTGAACTGACCCATGACGGGGCGACGTTCCGCTGCAGTGGAGCTGACAAGTCCTCGACATTCCAGTGTCAGTGTCGC
AACAATCCTTAGGGGGAATC

Downstream 100 bases:

>100_bases
ATGACAGGCGCATGTTGAGATGCATGAAGGGCTCTTTGCTTTGGCAAAGGGCCTTTTGCTTTCTTGAGGGTGACAATGCT
GGATTCTAAGATGAGTTGTC

Product: putative lactoylglutathione lyase

Products: glutathione; methylglyoxal

Alternate protein names: Glyoxalase Family Protein; Lactoylglutathione Lyase; Lactoylglutathione Lyase Protein; Glyoxalase; Glyoxalase/Bleomycin Resistance Protein; Glyoxalase/Dioxygenase; Lactoylglutathione Lyase-Like Lyase; Exported Glyoxalase; Asparaginyl-TRNA Synthetase; Dioxygenase; Glyoxalase Family Protein Family Protein; Lactoylgluthathione Lyase; Glyoxylase Protein

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
METNELHRGRLIDHLQLVVKDLDKTKRFYSAVFETLGIPMGGEGPGFFWCDELFISSADSPASAGKLTGRTHLAFQAKDR
DMVKKFYEVALQSGGQDNGAPGERPYHPGYYAAFVLDPDGNNIEAVFHGPAKKSAESVKITF

Sequences:

>Translated_142_residues
METNELHRGRLIDHLQLVVKDLDKTKRFYSAVFETLGIPMGGEGPGFFWCDELFISSADSPASAGKLTGRTHLAFQAKDR
DMVKKFYEVALQSGGQDNGAPGERPYHPGYYAAFVLDPDGNNIEAVFHGPAKKSAESVKITF
>Mature_142_residues
METNELHRGRLIDHLQLVVKDLDKTKRFYSAVFETLGIPMGGEGPGFFWCDELFISSADSPASAGKLTGRTHLAFQAKDR
DMVKKFYEVALQSGGQDNGAPGERPYHPGYYAAFVLDPDGNNIEAVFHGPAKKSAESVKITF

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.4.1.5

Molecular weight: Translated: 15639; Mature: 15639

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METNELHRGRLIDHLQLVVKDLDKTKRFYSAVFETLGIPMGGEGPGFFWCDELFISSADS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCC
PASAGKLTGRTHLAFQAKDRDMVKKFYEVALQSGGQDNGAPGERPYHPGYYAAFVLDPDG
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCC
NNIEAVFHGPAKKSAESVKITF
CCEEEEEECCCCCCCCEEEEEC
>Mature Secondary Structure
METNELHRGRLIDHLQLVVKDLDKTKRFYSAVFETLGIPMGGEGPGFFWCDELFISSADS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCC
PASAGKLTGRTHLAFQAKDRDMVKKFYEVALQSGGQDNGAPGERPYHPGYYAAFVLDPDG
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCC
NNIEAVFHGPAKKSAESVKITF
CCEEEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA