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The map label for this gene is prpC [H]

Identifier: 42522011

GI number: 42522011

Start: 374962

End: 375726

Strand: Direct

Name: prpC [H]

Synonym: Bd0397

Alternate gene names: 42522011

Gene position: 374962-375726 (Clockwise)

Preceding gene: 42522002

Following gene: 42522012

Centisome position: 9.91

GC content: 49.54

Gene sequence:

>765_bases
TTGACTCTTCTGTCGGTAGTGGGTGAAAATGATACAACTATGAAATTTGACTCGTGGTATCTGACAGATAAAGGTCTTCG
TCGTGATTCGAACCAGGATTCCTGCCTTATTAACCGGGAACTGGGATTATTCATTGTGGCGGATGGAATGGGCGGCCATA
TGGGCGGGGAAGTCGCTTCCAGCATGGCTGTGGAGACGGTTGAAGAAATCATGCTTCAGCCAGAAGCCACAAGAAAATCA
CCGCGCGAAGTGATTTTGCAAGCCTATGAAGAGGCTTCAAAACGCATTTTTGACAAGGCTGCCAATGAACGCCCCGAGCT
TGCCGGTATGGGCACCACGATGGTGATGGCCTACATCCGCGGCAAACATCTTTATGTCGGAAACGTCGGTGATTCCCGCT
GCTATTTGTTCAAGCGTCCGAACCTGTGGCAGATCACGGAAGATCATTCCCTGATCAATGAGCAGCTGCGGGCCGGCGTG
ATGAGTGAAGAGCAGGTGCGCCAGTTTGTGGGGCGAAATGTCATCACCCGCAGTGTAGGTTATGAGCGTGAAGTTTATCC
GGATATCATTGAGCGCGAGATCTTCCCTGGGGAAATTTTCCTCATGTGCTCCGACGGACTTTCCGGTTTGGTGGAAGATG
GAAGAATTTCTGAGATTTTAAATCAAAATACACCTGACAAAGCCGTAAAAGCCTGTGTAGAACAAGCCCTGGCAAATGGT
GGAGATGACAACGTCACAGTGATGCTGGTGCATTTCCACGAATAA

Upstream 100 bases:

>100_bases
TTCATAAGACCTCACCCCTTTCTATCGGTATTATGACACTTGAAATTGAGAAGATGGTGAGCTGGACTCAAAGATTGCGA
CCCAAGTCTAGGGCCAGACT

Downstream 100 bases:

>100_bases
TTGTGAATAGTTACTGATAGTTTTAGCGAAGATATCTAAGTAGGGGTCAAGGTTTGGATAAAAAGAAGGTCACGCTGTTT
ATTGTGAGCAATCAGACGGG

Product: protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTLLSVVGENDTTMKFDSWYLTDKGLRRDSNQDSCLINRELGLFIVADGMGGHMGGEVASSMAVETVEEIMLQPEATRKS
PREVILQAYEEASKRIFDKAANERPELAGMGTTMVMAYIRGKHLYVGNVGDSRCYLFKRPNLWQITEDHSLINEQLRAGV
MSEEQVRQFVGRNVITRSVGYEREVYPDIIEREIFPGEIFLMCSDGLSGLVEDGRISEILNQNTPDKAVKACVEQALANG
GDDNVTVMLVHFHE

Sequences:

>Translated_254_residues
MTLLSVVGENDTTMKFDSWYLTDKGLRRDSNQDSCLINRELGLFIVADGMGGHMGGEVASSMAVETVEEIMLQPEATRKS
PREVILQAYEEASKRIFDKAANERPELAGMGTTMVMAYIRGKHLYVGNVGDSRCYLFKRPNLWQITEDHSLINEQLRAGV
MSEEQVRQFVGRNVITRSVGYEREVYPDIIEREIFPGEIFLMCSDGLSGLVEDGRISEILNQNTPDKAVKACVEQALANG
GDDNVTVMLVHFHE
>Mature_253_residues
TLLSVVGENDTTMKFDSWYLTDKGLRRDSNQDSCLINRELGLFIVADGMGGHMGGEVASSMAVETVEEIMLQPEATRKSP
REVILQAYEEASKRIFDKAANERPELAGMGTTMVMAYIRGKHLYVGNVGDSRCYLFKRPNLWQITEDHSLINEQLRAGVM
SEEQVRQFVGRNVITRSVGYEREVYPDIIEREIFPGEIFLMCSDGLSGLVEDGRISEILNQNTPDKAVKACVEQALANGG
DDNVTVMLVHFHE

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 28444; Mature: 28313

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLSVVGENDTTMKFDSWYLTDKGLRRDSNQDSCLINRELGLFIVADGMGGHMGGEVAS
CCEEEEECCCCCEEEECCEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHH
SMAVETVEEIMLQPEATRKSPREVILQAYEEASKRIFDKAANERPELAGMGTTMVMAYIR
HHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
GKHLYVGNVGDSRCYLFKRPNLWQITEDHSLINEQLRAGVMSEEQVRQFVGRNVITRSVG
CCEEEEECCCCCEEEEEECCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHCC
YEREVYPDIIEREIFPGEIFLMCSDGLSGLVEDGRISEILNQNTPDKAVKACVEQALANG
CCCCCCHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHHHHCCCCCHHHHHHHHHHHHHCC
GDDNVTVMLVHFHE
CCCCEEEEEEEECC
>Mature Secondary Structure 
TLLSVVGENDTTMKFDSWYLTDKGLRRDSNQDSCLINRELGLFIVADGMGGHMGGEVAS
CEEEEECCCCCEEEECCEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHH
SMAVETVEEIMLQPEATRKSPREVILQAYEEASKRIFDKAANERPELAGMGTTMVMAYIR
HHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
GKHLYVGNVGDSRCYLFKRPNLWQITEDHSLINEQLRAGVMSEEQVRQFVGRNVITRSVG
CCEEEEECCCCCEEEEEECCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHCC
YEREVYPDIIEREIFPGEIFLMCSDGLSGLVEDGRISEILNQNTPDKAVKACVEQALANG
CCCCCCHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHHHHCCCCCHHHHHHHHHHHHHCC
GDDNVTVMLVHFHE
CCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]