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The map label for this gene is yueD [H]

Identifier: 42521949

GI number: 42521949

Start: 310754

End: 311509

Strand: Direct

Name: yueD [H]

Synonym: Bd0327

Alternate gene names: 42521949

Gene position: 310754-311509 (Clockwise)

Preceding gene: 42521946

Following gene: 42521950

Centisome position: 8.21

GC content: 48.54

Gene sequence:

>756_bases
ATGGATTTATTTATTGTTACCGGCGGTTCCAAGGGACTGGGGGAGCAGGTGTGTCTGCAAGCTCTTGAAAGAGGGCATCA
GGTCATCAACCTGTCGCGCACTCGGCCAAACATTAAGTCAGAGCGCTTTAAACATGTCACAGCCGATTTCAGTCGGGGAT
TGAAAACAGTTCAGAAAGTGGACTCTGTTCTGCAAGACATCTCGATGACGGCATTCAAAAAGATTCATCTGATCAACAAT
GCGGCGCTGATCAATCCGGTGGGCTCATTGGTGGATCTGGATCCGGCCGAGATGAACACCCACCTGGTCACGAATTTGAT
TTCTCCGCTATTGCTGTCACAAGTGTGTGCGCGGATTGCGACAGAAGAAAAGAAGCCGCTGACGGTCTTCAATATTGGGT
CCGGAGCTTCGTTCCGTCCTATTGCCGGGTGGTCGATGTATTGCTCCTCGAAAGCCGGTCTTAAGATGTTTACCGAGAAC
ACGGATTTGGATCTTCAGATGGCCAGGAACAAGAGGATCAAAATTTATCACTTCAGTCCCGGGGTTCTGGATACGCAGAT
GCAACAGACCATTCGTGGTTTAAAGAAAAAAGATTTTCCTGATGTCGCGAACTTCAAAAAGTTGAAGTCCGAAGACCAGC
TGCGCGATCCAGCGGATGTGGCGTCTTTGGTTGTCAGATTCTGCCTGTTCCCACAAACGTCTCAAGGTCAGTCATGTCTG
ATTACTGTTCAGGATTTAGAGGGGTCTTTGAAATGA

Upstream 100 bases:

>100_bases
GTCCAGCCAGTCTGGAGTCTGTTTCATTTTGTGTTCCCAATTCTGGACCTGATCTTCCATGTTTCTTGCTGAATGTCAGG
CCGAAATCCATAATTGAATC

Downstream 100 bases:

>100_bases
ATCGTACTTTCTTCTGTGCGGCAGTGATAGCGGTGTGTTTTTTGTTGGGCTTTAAGGTTGCTAATCCGGAAGGTGCGCCT
CGGGCGGGAAAAGAAGATCT

Product: hypothetical protein

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MDLFIVTGGSKGLGEQVCLQALERGHQVINLSRTRPNIKSERFKHVTADFSRGLKTVQKVDSVLQDISMTAFKKIHLINN
AALINPVGSLVDLDPAEMNTHLVTNLISPLLLSQVCARIATEEKKPLTVFNIGSGASFRPIAGWSMYCSSKAGLKMFTEN
TDLDLQMARNKRIKIYHFSPGVLDTQMQQTIRGLKKKDFPDVANFKKLKSEDQLRDPADVASLVVRFCLFPQTSQGQSCL
ITVQDLEGSLK

Sequences:

>Translated_251_residues
MDLFIVTGGSKGLGEQVCLQALERGHQVINLSRTRPNIKSERFKHVTADFSRGLKTVQKVDSVLQDISMTAFKKIHLINN
AALINPVGSLVDLDPAEMNTHLVTNLISPLLLSQVCARIATEEKKPLTVFNIGSGASFRPIAGWSMYCSSKAGLKMFTEN
TDLDLQMARNKRIKIYHFSPGVLDTQMQQTIRGLKKKDFPDVANFKKLKSEDQLRDPADVASLVVRFCLFPQTSQGQSCL
ITVQDLEGSLK
>Mature_251_residues
MDLFIVTGGSKGLGEQVCLQALERGHQVINLSRTRPNIKSERFKHVTADFSRGLKTVQKVDSVLQDISMTAFKKIHLINN
AALINPVGSLVDLDPAEMNTHLVTNLISPLLLSQVCARIATEEKKPLTVFNIGSGASFRPIAGWSMYCSSKAGLKMFTEN
TDLDLQMARNKRIKIYHFSPGVLDTQMQQTIRGLKKKDFPDVANFKKLKSEDQLRDPADVASLVVRFCLFPQTSQGQSCL
ITVQDLEGSLK

Specific function: Reduces benzil stereospecifically to (S)-benzoin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI115534694, Length=189, Percent_Identity=28.042328042328, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322227, Length=249, Percent_Identity=24.4979919678715, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=253, Percent_Identity=26.8774703557312, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI23397609, Length=198, Percent_Identity=30.8080808080808, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 27835; Mature: 27835

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFIVTGGSKGLGEQVCLQALERGHQVINLSRTRPNIKSERFKHVTADFSRGLKTVQKV
CEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DSVLQDISMTAFKKIHLINNAALINPVGSLVDLDPAEMNTHLVTNLISPLLLSQVCARIA
HHHHHHHHHHHHHHHHHHCCCCEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TEEKKPLTVFNIGSGASFRPIAGWSMYCSSKAGLKMFTENTDLDLQMARNKRIKIYHFSP
CCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCEEEECCCCCEEEECCCCEEEEEEECC
GVLDTQMQQTIRGLKKKDFPDVANFKKLKSEDQLRDPADVASLVVRFCLFPQTSQGQSCL
CCCHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCEEE
ITVQDLEGSLK
EEEECCCCCCC
>Mature Secondary Structure
MDLFIVTGGSKGLGEQVCLQALERGHQVINLSRTRPNIKSERFKHVTADFSRGLKTVQKV
CEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DSVLQDISMTAFKKIHLINNAALINPVGSLVDLDPAEMNTHLVTNLISPLLLSQVCARIA
HHHHHHHHHHHHHHHHHHCCCCEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TEEKKPLTVFNIGSGASFRPIAGWSMYCSSKAGLKMFTENTDLDLQMARNKRIKIYHFSP
CCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCEEEECCCCCEEEECCCCEEEEEEECC
GVLDTQMQQTIRGLKKKDFPDVANFKKLKSEDQLRDPADVASLVVRFCLFPQTSQGQSCL
CCCHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCEEE
ITVQDLEGSLK
EEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]