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The map label for this gene is qor [H]

Identifier: 42521928

GI number: 42521928

Start: 294495

End: 295475

Strand: Direct

Name: qor [H]

Synonym: Bd0305

Alternate gene names: 42521928

Gene position: 294495-295475 (Clockwise)

Preceding gene: 42521926

Following gene: 42521930

Centisome position: 7.78

GC content: 55.25

Gene sequence:

>981_bases
ATGCGTGCAGTTGAAATCACCCAACCCGGCGGACCTGAAGTTTTAAAAATCACCGAACGAACCAAGCCTGAACCTGCCAT
CGGCGAAGTGCTGATCGAGATCCATGCCTCGGGTGTGAATCGTCCGGACTGCGCGCAAAGACAGGGAACTTATCCACCAC
CTCCGGGGGCCTCCGATATTCCGGGGCTTGAGATTGCCGGAAAGATTGTGGCCGTGGGTGCGGGTGTCAGCAAATGGAAA
GTCGGCGACATGGTGTGTGCGCTGGTTTCTGGTGGTGGTTATGCTGAATACGTTGCGGCCCCTGAGGGGCAGTGCCTGCC
TGTTCCAACGGGAATGAGTGTTGTTGAAGCCGCCGCTTTGCCAGAGACCTTCTTCACCGTTTGGACCAACTTGTTTGAAA
GCGGTCGCCTGCAAAAAGGCGAAAGTGTTCTGATTCACGGCGGAGCCGGCGGCATCGGCACGACGGCCATTCAAATGGCC
TCGGCCATGGGTGTGCGGGTTTTCACGACGGTGGGGAAAAAGGAATCCGTATCGATATGTCAGGAGCTGGGGGCTGAACG
AGTGATCCTGTACAAGGAAGAGGATTTTGTCAGTGTGGTGAAATCACTTACGGCTGACAAGGGTGTGGATGTGATTCTGG
ATATGGTGGGTGGGGATTACTTTGCCCGCAATATTGAGGCCCTGGCCGTCCAGGGGCGGCTGGTGCAGATCGCAACGATG
CAAGGGGCGAAGGTGGAGCTGGATTTGCGCAAAGTGATGTTTAAGCGTCTGACTTTGACAGGTTCAACCCTGCGCGCACG
CCCGGTCGCAGAAAAATCCCGCATTGCCACGGCGTTGTTGCAGAATATCTGGCCGCTCTTGAATAAAAATCAAATGCGAC
CGGTGATTTATAAAGTTTTGAAACTGGAACAGGCCGCTGAGGCCCACGCGATGATGGAAGCCAGTCAGCACACCGGAAAG
ATTGTGCTGACGACCCGTTAG

Upstream 100 bases:

>100_bases
GGGCTTAACGCCCGGCAACTGGCCTATGGCCCAGTTTCAAAGTCTTGACGACGGAAAAACAGGGGCGCATTTTGAATTAT
TCCCAGAAGGAGTCACTTTC

Downstream 100 bases:

>100_bases
ACAAGTTTATTCCAAGTGCTCTCTTTGACGGGAGCTCTTGTCGCATTTGCCGGTGAAGGCATGATTCACAGCGCGCTGTT
TCGGCGCGTTTTCAAAGAAG

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MRAVEITQPGGPEVLKITERTKPEPAIGEVLIEIHASGVNRPDCAQRQGTYPPPPGASDIPGLEIAGKIVAVGAGVSKWK
VGDMVCALVSGGGYAEYVAAPEGQCLPVPTGMSVVEAAALPETFFTVWTNLFESGRLQKGESVLIHGGAGGIGTTAIQMA
SAMGVRVFTTVGKKESVSICQELGAERVILYKEEDFVSVVKSLTADKGVDVILDMVGGDYFARNIEALAVQGRLVQIATM
QGAKVELDLRKVMFKRLTLTGSTLRARPVAEKSRIATALLQNIWPLLNKNQMRPVIYKVLKLEQAAEAHAMMEASQHTGK
IVLTTR

Sequences:

>Translated_326_residues
MRAVEITQPGGPEVLKITERTKPEPAIGEVLIEIHASGVNRPDCAQRQGTYPPPPGASDIPGLEIAGKIVAVGAGVSKWK
VGDMVCALVSGGGYAEYVAAPEGQCLPVPTGMSVVEAAALPETFFTVWTNLFESGRLQKGESVLIHGGAGGIGTTAIQMA
SAMGVRVFTTVGKKESVSICQELGAERVILYKEEDFVSVVKSLTADKGVDVILDMVGGDYFARNIEALAVQGRLVQIATM
QGAKVELDLRKVMFKRLTLTGSTLRARPVAEKSRIATALLQNIWPLLNKNQMRPVIYKVLKLEQAAEAHAMMEASQHTGK
IVLTTR
>Mature_326_residues
MRAVEITQPGGPEVLKITERTKPEPAIGEVLIEIHASGVNRPDCAQRQGTYPPPPGASDIPGLEIAGKIVAVGAGVSKWK
VGDMVCALVSGGGYAEYVAAPEGQCLPVPTGMSVVEAAALPETFFTVWTNLFESGRLQKGESVLIHGGAGGIGTTAIQMA
SAMGVRVFTTVGKKESVSICQELGAERVILYKEEDFVSVVKSLTADKGVDVILDMVGGDYFARNIEALAVQGRLVQIATM
QGAKVELDLRKVMFKRLTLTGSTLRARPVAEKSRIATALLQNIWPLLNKNQMRPVIYKVLKLEQAAEAHAMMEASQHTGK
IVLTTR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=40.8536585365854, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=40.8536585365854, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=33.7386018237082, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=33.7386018237082, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=31.6109422492401, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI24308257, Length=341, Percent_Identity=29.0322580645161, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI18379349, Length=340, Percent_Identity=30.8823529411765, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI28557745, Length=234, Percent_Identity=34.1880341880342, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI197927207, Length=198, Percent_Identity=30.3030303030303, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI41872631, Length=310, Percent_Identity=26.4516129032258, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI47519420, Length=370, Percent_Identity=26.4864864864865, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI67078404, Length=244, Percent_Identity=27.4590163934426, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI67078406, Length=237, Percent_Identity=27.8481012658228, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1790485, Length=247, Percent_Identity=35.2226720647773, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17507255, Length=309, Percent_Identity=29.126213592233, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17536829, Length=256, Percent_Identity=28.515625, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71987554, Length=350, Percent_Identity=26.5714285714286, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212642053, Length=308, Percent_Identity=25.6493506493506, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=329, Percent_Identity=29.1793313069909, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323961, Length=334, Percent_Identity=28.4431137724551, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324486, Length=334, Percent_Identity=27.8443113772455, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=26.2048192771084, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=282, Percent_Identity=26.9503546099291, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221330659, Length=269, Percent_Identity=26.0223048327138, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19920632, Length=269, Percent_Identity=26.0223048327138, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24581345, Length=269, Percent_Identity=25.6505576208178, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI45550423, Length=266, Percent_Identity=26.6917293233083, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34777; Mature: 34777

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVEITQPGGPEVLKITERTKPEPAIGEVLIEIHASGVNRPDCAQRQGTYPPPPGASDI
CCEEEECCCCCCCEEEEECCCCCCCCHHHEEEEEECCCCCCCCHHHCCCCCCCCCCCCCC
PGLEIAGKIVAVGAGVSKWKVGDMVCALVSGGGYAEYVAAPEGQCLPVPTGMSVVEAAAL
CCCHHCCEEEEECCCCCCCCHHHHHEEEECCCCCEEEEECCCCCEEECCCCHHHHHHHHC
PETFFTVWTNLFESGRLQKGESVLIHGGAGGIGTTAIQMASAMGVRVFTTVGKKESVSIC
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHH
QELGAERVILYKEEDFVSVVKSLTADKGVDVILDMVGGDYFARNIEALAVQGRLVQIATM
HHCCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCHHEEEECCEEEEEEEC
QGAKVELDLRKVMFKRLTLTGSTLRARPVAEKSRIATALLQNIWPLLNKNQMRPVIYKVL
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KLEQAAEAHAMMEASQHTGKIVLTTR
HHHHHHHHHHHHHHHCCCCEEEEEEC
>Mature Secondary Structure
MRAVEITQPGGPEVLKITERTKPEPAIGEVLIEIHASGVNRPDCAQRQGTYPPPPGASDI
CCEEEECCCCCCCEEEEECCCCCCCCHHHEEEEEECCCCCCCCHHHCCCCCCCCCCCCCC
PGLEIAGKIVAVGAGVSKWKVGDMVCALVSGGGYAEYVAAPEGQCLPVPTGMSVVEAAAL
CCCHHCCEEEEECCCCCCCCHHHHHEEEECCCCCEEEEECCCCCEEECCCCHHHHHHHHC
PETFFTVWTNLFESGRLQKGESVLIHGGAGGIGTTAIQMASAMGVRVFTTVGKKESVSIC
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHH
QELGAERVILYKEEDFVSVVKSLTADKGVDVILDMVGGDYFARNIEALAVQGRLVQIATM
HHCCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCHHEEEECCEEEEEEEC
QGAKVELDLRKVMFKRLTLTGSTLRARPVAEKSRIATALLQNIWPLLNKNQMRPVIYKVL
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KLEQAAEAHAMMEASQHTGKIVLTTR
HHHHHHHHHHHHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]