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The map label for this gene is dapE [H]

Identifier: 42521766

GI number: 42521766

Start: 112926

End: 114272

Strand: Direct

Name: dapE [H]

Synonym: Bd0129

Alternate gene names: 42521766

Gene position: 112926-114272 (Clockwise)

Preceding gene: 42521765

Following gene: 42521767

Centisome position: 2.99

GC content: 52.71

Gene sequence:

>1347_bases
TTGGACTTCATCGAGGCCTGCCGACAACTGATCGCTATCGACAGCTCACCCACTCACGGCAATAAAGAATTGTCCAAGTG
GGTGGCGGCCTTTTGCCGTCAGCGTGGATTGCACGTTGAAGAGCAAGAGGAGGTTGTCGGGGACCTTGAACAGGCGAATG
TGATTGCCCGTCCGGTGGCGGAGCGCCCGGAAGCCGAGTTCCTGCTGCAAACGCATCTGGACACGGTGGATCCGGGGCCG
TTCTCGCTTTGGACAGATACGGGCAGCAATCCGTTTGATGCCCATATCATCGACGGAAAAATCCACGGCCTGGGGGCCGC
GGATGTAAAGCTCGACTTCTTGTGCAAACTAGAAGCGCTGGCATCGTTCGGACCTGATCGCAAATGGCGTTTGCCGCCAG
TCCTGGTGGGGACCTTTGGGGAAGAGTCCGGCATGCAAGGGGCCCTGAAGCTGATTCGCAAAAACAAGATTTCTGCGAAG
ATGGCGTTGATCGGGGAGCCCAGTGATCTGCGAGTGATCAATGCGGCGAAAGGTTTTGCCAGTGTTGAAATTCACGTGCC
GTTCTCGGATGAAGAGATGCGCTATCGGGAAGAACACAACCTGCGCGAAAGCACCTCGACGCAGTCTAAGATTTTCCGCG
GTAAAGCGGCGCACTCTTCCACGCCGCATCTGGGGGAAAGTGCGATAGCCAAGATGTTTGAATATCTCATGATGCTGCCG
GATTCGGTGAACGTCATGGAGATGGATGGCGGAATCAATTTCAACACTGTTCCCAGCCATGCATTCTTGGAAATCGATAT
GGTGAACCAGATCCCTGAGCCCATTTCACGTAAGATTGCCAATATCTATCGTGCGGTGAAAGCTCTGGAGCTGGAGTTTT
TGGATCATAAAGATGACGATTTTTATCCGACCACGCCGACATTGAACATTGGACTGATCCGCACCAATGAAGGCGACATT
CAGATTTCCGGTTCGTGCCGGATTCCTCCGGTGATCACGCATGAAATCTATGAAGGCTGGATGGATCGTCTGCGCCAGGT
GTGCGAAGCCAATGGCGCCACCTTCCGCGTGAATGACTATAAAAAGCCCTTCCGCACCGAAGTGACTTCGATTCTTGCAA
AAGGGTGTCTGGATGAATTGCGGGCGATGGGACTTGATGACAAGCCAATCACCCAGGCCTCAACAAATGAAGCCAGCATC
TTCACCCGCGTGGGTATTGAGTGTGTGTGTTTTGGTCCCGGTAAAAGGGAAGGAAACGTGCACACCCCTCAGGAGCACGT
CTCTATAGAGGATCTGCACAAGGCTATTGAGTTTTATAAAAGGATCATCGAAAGGTTTTGTTTATGA

Upstream 100 bases:

>100_bases
TCCGGTTCGCGCCCGTTTCCTGGTGCCGGCGATCATTGAAGACGCTGACATCGACATCGCTTTGAAAGCGATCGAAAAAA
CTTTGCTTGAAGGAGTCTAG

Downstream 100 bases:

>100_bases
GTTTCATAATACGTCCGGTACATCACGATGATTTGAATCAACTGGTGGACCTTGCCAAGCAGTTCAATCTTTTGAACCTG
CCTGGCGATAAAAAAGTGAT

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MDFIEACRQLIAIDSSPTHGNKELSKWVAAFCRQRGLHVEEQEEVVGDLEQANVIARPVAERPEAEFLLQTHLDTVDPGP
FSLWTDTGSNPFDAHIIDGKIHGLGAADVKLDFLCKLEALASFGPDRKWRLPPVLVGTFGEESGMQGALKLIRKNKISAK
MALIGEPSDLRVINAAKGFASVEIHVPFSDEEMRYREEHNLRESTSTQSKIFRGKAAHSSTPHLGESAIAKMFEYLMMLP
DSVNVMEMDGGINFNTVPSHAFLEIDMVNQIPEPISRKIANIYRAVKALELEFLDHKDDDFYPTTPTLNIGLIRTNEGDI
QISGSCRIPPVITHEIYEGWMDRLRQVCEANGATFRVNDYKKPFRTEVTSILAKGCLDELRAMGLDDKPITQASTNEASI
FTRVGIECVCFGPGKREGNVHTPQEHVSIEDLHKAIEFYKRIIERFCL

Sequences:

>Translated_448_residues
MDFIEACRQLIAIDSSPTHGNKELSKWVAAFCRQRGLHVEEQEEVVGDLEQANVIARPVAERPEAEFLLQTHLDTVDPGP
FSLWTDTGSNPFDAHIIDGKIHGLGAADVKLDFLCKLEALASFGPDRKWRLPPVLVGTFGEESGMQGALKLIRKNKISAK
MALIGEPSDLRVINAAKGFASVEIHVPFSDEEMRYREEHNLRESTSTQSKIFRGKAAHSSTPHLGESAIAKMFEYLMMLP
DSVNVMEMDGGINFNTVPSHAFLEIDMVNQIPEPISRKIANIYRAVKALELEFLDHKDDDFYPTTPTLNIGLIRTNEGDI
QISGSCRIPPVITHEIYEGWMDRLRQVCEANGATFRVNDYKKPFRTEVTSILAKGCLDELRAMGLDDKPITQASTNEASI
FTRVGIECVCFGPGKREGNVHTPQEHVSIEDLHKAIEFYKRIIERFCL
>Mature_448_residues
MDFIEACRQLIAIDSSPTHGNKELSKWVAAFCRQRGLHVEEQEEVVGDLEQANVIARPVAERPEAEFLLQTHLDTVDPGP
FSLWTDTGSNPFDAHIIDGKIHGLGAADVKLDFLCKLEALASFGPDRKWRLPPVLVGTFGEESGMQGALKLIRKNKISAK
MALIGEPSDLRVINAAKGFASVEIHVPFSDEEMRYREEHNLRESTSTQSKIFRGKAAHSSTPHLGESAIAKMFEYLMMLP
DSVNVMEMDGGINFNTVPSHAFLEIDMVNQIPEPISRKIANIYRAVKALELEFLDHKDDDFYPTTPTLNIGLIRTNEGDI
QISGSCRIPPVITHEIYEGWMDRLRQVCEANGATFRVNDYKKPFRTEVTSILAKGCLDELRAMGLDDKPITQASTNEASI
FTRVGIECVCFGPGKREGNVHTPQEHVSIEDLHKAIEFYKRIIERFCL

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=252, Percent_Identity=29.3650793650794, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 50149; Mature: 50149

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFIEACRQLIAIDSSPTHGNKELSKWVAAFCRQRGLHVEEQEEVVGDLEQANVIARPVA
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCC
ERPEAEFLLQTHLDTVDPGPFSLWTDTGSNPFDAHIIDGKIHGLGAADVKLDFLCKLEAL
CCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEECCEEECCCCCCEEHHHHHHHHHH
ASFGPDRKWRLPPVLVGTFGEESGMQGALKLIRKNKISAKMALIGEPSDLRVINAAKGFA
HHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCE
SVEIHVPFSDEEMRYREEHNLRESTSTQSKIFRGKAAHSSTPHLGESAIAKMFEYLMMLP
EEEEEECCCCHHHHHHHHHCHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
DSVNVMEMDGGINFNTVPSHAFLEIDMVNQIPEPISRKIANIYRAVKALELEFLDHKDDD
CCCCEEEECCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FYPTTPTLNIGLIRTNEGDIQISGSCRIPPVITHEIYEGWMDRLRQVCEANGATFRVNDY
CCCCCCCEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
KKPFRTEVTSILAKGCLDELRAMGLDDKPITQASTNEASIFTRVGIECVCFGPGKREGNV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEECCEEEEEECCCCCCCCC
HTPQEHVSIEDLHKAIEFYKRIIERFCL
CCCHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFIEACRQLIAIDSSPTHGNKELSKWVAAFCRQRGLHVEEQEEVVGDLEQANVIARPVA
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCC
ERPEAEFLLQTHLDTVDPGPFSLWTDTGSNPFDAHIIDGKIHGLGAADVKLDFLCKLEAL
CCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEECCEEECCCCCCEEHHHHHHHHHH
ASFGPDRKWRLPPVLVGTFGEESGMQGALKLIRKNKISAKMALIGEPSDLRVINAAKGFA
HHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCE
SVEIHVPFSDEEMRYREEHNLRESTSTQSKIFRGKAAHSSTPHLGESAIAKMFEYLMMLP
EEEEEECCCCHHHHHHHHHCHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
DSVNVMEMDGGINFNTVPSHAFLEIDMVNQIPEPISRKIANIYRAVKALELEFLDHKDDD
CCCCEEEECCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FYPTTPTLNIGLIRTNEGDIQISGSCRIPPVITHEIYEGWMDRLRQVCEANGATFRVNDY
CCCCCCCEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
KKPFRTEVTSILAKGCLDELRAMGLDDKPITQASTNEASIFTRVGIECVCFGPGKREGNV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEECCEEEEEECCCCCCCCC
HTPQEHVSIEDLHKAIEFYKRIIERFCL
CCCHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA