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The map label for this gene is murA

Identifier: 42521717

GI number: 42521717

Start: 64492

End: 65736

Strand: Direct

Name: murA

Synonym: Bd0071

Alternate gene names: 42521717

Gene position: 64492-65736 (Clockwise)

Preceding gene: 42521716

Following gene: 42521721

Centisome position: 1.7

GC content: 53.41

Gene sequence:

>1245_bases
ATGGTCGTCATGGGCAATGGCCCACTAAAAGGTACTGTCGCTACGAGCGGCGCAAAGAACGCTGCTCTGCCAATTTTGTT
TTCGACTCTTCTTGCTGAGGGCAACCACGTCTTCACAAATATGCCGAAACTGAAGGATATCGAATCCACTTCTGAACTTC
TGAACAGCCTGGGCTGCGAAACGAAGTGGGTGGGTGATGAGTTTCACGTCACGGTGAACAAACCTTCTTCTTTCGAAGCG
TCTTACGACCTGGTTCGCAAGATGCGCGCAAGCTTCCTGTGCATGGGCCCGATGCTGGCAAAATACGGTGAAGCCGTTGT
GTCCCAGCCGGGGGGGTGTGCTATCGGAAGCCGTCCGATTGATTTGCATTTGGACGGTTTCAGAGCTTTGGGTGCCACAA
TCACACAAAAAGAAGGTTACGTTCACGCAGGTTCCCCAAAACTAAAAGGTGGAACCTTCCTGTTTGAAACTGTGACCGTG
GGTGGAACTGAGAACGTGATGATGGCAGCAACCCTTGCTGACGGTGTCACGGTTCTTGAAAACGCTGCCAAAGAACCCGA
GATCGTGGATCTGGCCGAATATCTGAACAAGATGGGCGCCAAGATCACCGGTCACGGCACCAGCGTGATTCGTATTGAAG
GCGTGGCAAAACTGACGCCGGCCAAACACTCCATCATGCCGGATCGTATCGAAGCAGGAACTTTGCTGATTGCAGGTGCG
ATCACCAAAGGACAAGTGACGGTGACCAAATGTGTGCCGGCTCACCTGGAGGCATTGATCCTGAAAATGCGCGAAGCGGG
TTTCAAGATTGAAACGACCAAAGATACCATGACGGTCTTCCCTTGTGATCAGTGGGAGGCGGTGGATATCACGACGGCCC
CTCACCCCTTGTTCCCGACAGATCTTCAGGCGCAGTTCATGGCGTTGATGACGGTGGCTCACGGGACCAGTGTTATCACT
GAAACCGTTTTTGAAAACCGTTTCATGCACGTGACTGAATTGTCCCGCTTGGGTGCGGATATCACTCCGAAAACCCGCGT
GGCCGTTGTGCGTGGTTGCCCGGGTAAACTGACGGGCGCCCCGGTAATGGCAACGGACTTGCGTGCCAGTGCTTCCTTGG
TGCTGGCGGGCCTGGTGGCTTCGGGTGAAACCGTTGTCAGCCGCATCTATCACCTGGATCGTGGATACGAAAAGCTTGAA
GACAAGCTTTCATCCCTGGGTGCGAAGATTCGCAGAATTGAATAA

Upstream 100 bases:

>100_bases
AAGCAGGCCTATGAAAGCTTAAAAATATTTAACGAAATCAGTGTCATCAAAGATCTTTCTGGGCATGATAGAGTCATCCG
CGGAGAAACACATGGATAAA

Downstream 100 bases:

>100_bases
CAAAGAAAAGGCTCCTTCACGGAGCCTTTTTTATTTCTGCGAACTATCTTCCAACACAAGCTTTGATGGCTTTGCTGAAC
GCCGAAGATCCGGTGATGGA

Product: UDP-N-acetylglucosamine enolpyruvyl transferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MVVMGNGPLKGTVATSGAKNAALPILFSTLLAEGNHVFTNMPKLKDIESTSELLNSLGCETKWVGDEFHVTVNKPSSFEA
SYDLVRKMRASFLCMGPMLAKYGEAVVSQPGGCAIGSRPIDLHLDGFRALGATITQKEGYVHAGSPKLKGGTFLFETVTV
GGTENVMMAATLADGVTVLENAAKEPEIVDLAEYLNKMGAKITGHGTSVIRIEGVAKLTPAKHSIMPDRIEAGTLLIAGA
ITKGQVTVTKCVPAHLEALILKMREAGFKIETTKDTMTVFPCDQWEAVDITTAPHPLFPTDLQAQFMALMTVAHGTSVIT
ETVFENRFMHVTELSRLGADITPKTRVAVVRGCPGKLTGAPVMATDLRASASLVLAGLVASGETVVSRIYHLDRGYEKLE
DKLSSLGAKIRRIE

Sequences:

>Translated_414_residues
MVVMGNGPLKGTVATSGAKNAALPILFSTLLAEGNHVFTNMPKLKDIESTSELLNSLGCETKWVGDEFHVTVNKPSSFEA
SYDLVRKMRASFLCMGPMLAKYGEAVVSQPGGCAIGSRPIDLHLDGFRALGATITQKEGYVHAGSPKLKGGTFLFETVTV
GGTENVMMAATLADGVTVLENAAKEPEIVDLAEYLNKMGAKITGHGTSVIRIEGVAKLTPAKHSIMPDRIEAGTLLIAGA
ITKGQVTVTKCVPAHLEALILKMREAGFKIETTKDTMTVFPCDQWEAVDITTAPHPLFPTDLQAQFMALMTVAHGTSVIT
ETVFENRFMHVTELSRLGADITPKTRVAVVRGCPGKLTGAPVMATDLRASASLVLAGLVASGETVVSRIYHLDRGYEKLE
DKLSSLGAKIRRIE
>Mature_414_residues
MVVMGNGPLKGTVATSGAKNAALPILFSTLLAEGNHVFTNMPKLKDIESTSELLNSLGCETKWVGDEFHVTVNKPSSFEA
SYDLVRKMRASFLCMGPMLAKYGEAVVSQPGGCAIGSRPIDLHLDGFRALGATITQKEGYVHAGSPKLKGGTFLFETVTV
GGTENVMMAATLADGVTVLENAAKEPEIVDLAEYLNKMGAKITGHGTSVIRIEGVAKLTPAKHSIMPDRIEAGTLLIAGA
ITKGQVTVTKCVPAHLEALILKMREAGFKIETTKDTMTVFPCDQWEAVDITTAPHPLFPTDLQAQFMALMTVAHGTSVIT
ETVFENRFMHVTELSRLGADITPKTRVAVVRGCPGKLTGAPVMATDLRASASLVLAGLVASGETVVSRIYHLDRGYEKLE
DKLSSLGAKIRRIE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=414, Percent_Identity=52.1739130434783, Blast_Score=417, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_BDEBA (Q6MRK7)

Other databases:

- EMBL:   BX842646
- RefSeq:   NP_967097.1
- ProteinModelPortal:   Q6MRK7
- SMR:   Q6MRK7
- GeneID:   2733269
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd0071
- NMPDR:   fig|264462.1.peg.67
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q6MRK7
- BioCyc:   BBAC264462:BD0071-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44168; Mature: 44168

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: ACT_SITE 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVMGNGPLKGTVATSGAKNAALPILFSTLLAEGNHVFTNMPKLKDIESTSELLNSLGCE
CEEECCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCC
TKWVGDEFHVTVNKPSSFEASYDLVRKMRASFLCMGPMLAKYGEAVVSQPGGCAIGSRPI
EEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCE
DLHLDGFRALGATITQKEGYVHAGSPKLKGGTFLFETVTVGGTENVMMAATLADGVTVLE
EEEECCHHHHCCEEECCCCEEECCCCCCCCCEEEEEEEEECCCCCEEEEEEHHCCHHHHH
NAAKEPEIVDLAEYLNKMGAKITGHGTSVIRIEGVAKLTPAKHSIMPDRIEAGTLLIAGA
HCCCCCCHHHHHHHHHHHCCEEECCCCEEEEECCCEEECCCHHCCCCCCCCCCEEEEEEE
ITKGQVTVTKCVPAHLEALILKMREAGFKIETTKDTMTVFPCDQWEAVDITTAPHPLFPT
CCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCEEEEECCCCCCCCC
DLQAQFMALMTVAHGTSVITETVFENRFMHVTELSRLGADITPKTRVAVVRGCPGKLTGA
CHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCC
PVMATDLRASASLVLAGLVASGETVVSRIYHLDRGYEKLEDKLSSLGAKIRRIE
CEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCHHHCCCC
>Mature Secondary Structure
MVVMGNGPLKGTVATSGAKNAALPILFSTLLAEGNHVFTNMPKLKDIESTSELLNSLGCE
CEEECCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCC
TKWVGDEFHVTVNKPSSFEASYDLVRKMRASFLCMGPMLAKYGEAVVSQPGGCAIGSRPI
EEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCE
DLHLDGFRALGATITQKEGYVHAGSPKLKGGTFLFETVTVGGTENVMMAATLADGVTVLE
EEEECCHHHHCCEEECCCCEEECCCCCCCCCEEEEEEEEECCCCCEEEEEEHHCCHHHHH
NAAKEPEIVDLAEYLNKMGAKITGHGTSVIRIEGVAKLTPAKHSIMPDRIEAGTLLIAGA
HCCCCCCHHHHHHHHHHHCCEEECCCCEEEEECCCEEECCCHHCCCCCCCCCCEEEEEEE
ITKGQVTVTKCVPAHLEALILKMREAGFKIETTKDTMTVFPCDQWEAVDITTAPHPLFPT
CCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCEEEEECCCCCCCCC
DLQAQFMALMTVAHGTSVITETVFENRFMHVTELSRLGADITPKTRVAVVRGCPGKLTGA
CHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCC
PVMATDLRASASLVLAGLVASGETVVSRIYHLDRGYEKLEDKLSSLGAKIRRIE
CEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA