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The map label for this gene is rho [H]

Identifier: 42521712

GI number: 42521712

Start: 59532

End: 61277

Strand: Direct

Name: rho [H]

Synonym: Bd0065

Alternate gene names: 42521712

Gene position: 59532-61277 (Clockwise)

Preceding gene: 42521710

Following gene: 42521714

Centisome position: 1.57

GC content: 51.55

Gene sequence:

>1746_bases
TTGTCTGAACCTAAAGATCAACAAGGCGTTGAGGTGGCAAAAAAACGTACTCGCACTGCGAAGAGTACATCTGAAGATAC
CTCCGCCCCCGCTGCTGAAGCTTCCCCAGCTCCGGCCGCCGAAGCCGCCCCTGCGGCCCCAGCACCTTCCGAAAATGCCC
CTGTTTCAGCAGCTCCTGCCGCTGCTCCGGAAGCCCGCCAAGACAGACCTCAACAGCAAAACCAACAACGCCGTGAATTC
CGCCCGCACAATCGCGACAACCGTGATCGTGGCGATCGCAATGACCGCGGCGACCGTAACGACCGTGGCGACAGAAATGA
TCGTGGTGGTCACCGTGGTGATCGTGGCAATAATCAGCGCCGCGACTTCCGTCATGACCGTGGCCGCGATGAAGCCCAGC
CAATGGGTGACGATGCTCACTCAGCGATGCCGGCCCAGGTTCAGGACGTGGATTTAGCGGACATCTCTTTGACTGATGAG
GAAAAGAGCTGGTTGTCCTCCAAGGACTTGAAATCAAAAAACATCACGCAGCTGACAGAGCTTGCGAACAAACTGAAAAT
CGAAAACGCTGCCGGTCTTCGCCGTCAGGACATGATCTTCGAAATTCTGAAACGTGCCGCGAAACTGGGTCAGGACATTT
ATGGTTCTGGCGTTCTGGAAATCCTTCCGGACGGTTACGGATTCTTGCGTTCTCCGGATTACAACTATCTTCCAGGTCCG
GATGATATCTATGTATCTCCGTCCCAGATCCGTCGTTTCGGCCTAAGAACCGGTGACACCGTGACGGGAACTGTTCGCCC
GCCGAAAGATGGCGAGCGTTACTTTGCATTGTTGAAAGTGGATTCTCTGAACTTCGAGACCACTGAAAAAGGCAAAGACA
AGATCCTGTTCGACAACTTGACGCCGCTTTATCCGAATGAACGCCTGAAGCTGGAACACAACCCTGGTGAATACACCACG
CGTGTTGTGGACCTGATGGCTCCGTTGGGTAAAGGTCAGCGTGCCTTGATTGTTGCCCCACCAAGAACAGGTAAAACCGT
TCTGATGCAGCAAATTGCCAATGCGATCACACACAATCATCCGGAAGTGAAATTGATCGTTCTTCTGATCGATGAACGTC
CGGAAGAGGTGACCGACATGCAACGTACCGTAAAAGGTGAAGTTGTTTCGTCCACGTTCGATGAGCCACCAACTCGTCAC
GTTCAGGTTGCCGAGATGGTTATCGAAAAAGCAAAACGTTTGGTTGAACACAAACATGACGTTGTAATCCTGCTGGATTC
CATCACTCGTCTGGCGCGTGCCTATAACACCGTTGTTCCTCCATCCGGTAAAATTCTGTCTGGTGGTGTGGACTCCAACG
CCCTTCACAAACCAAAACGTTTCTTCGGTGCGGCTCGTAACATTGAAGAAGGCGGATCTTTGACTATCATCGCGACGGCT
TTGATCGATACGGGTTCCCGTATGGATGAGGTTATCTTCGAGGAGTTTAAAGGTACTGGTAATGCTGAGATCCATTTGGA
TCGCAAGCTGATGGAAAAACGTATCTTCCCTTGCATGGACATCAACAAATCCGGCACTCGTAAAGAGGACCTGTTGGTTG
ATAAAGCGGACTTGAACCGTCTGTGGATCCTGAGAAAAGTTTTGGCGCCAATGAACGTTATCGACGCGATGGAATTCCTG
ATCGATAAAGTTGAAGGTACAAAAACGAACAACGACTTCCTGAAAGCGATGTCCGGACCGGGCTAA

Upstream 100 bases:

>100_bases
AAGGACAGTGAGGTCATAACGAATAAGCATGAATCCAATCGGATCAGCTTCCTATATATATCGCTCTTTTTTCTGATTAA
ATCCTACAAGGAGAATTTGT

Downstream 100 bases:

>100_bases
GCTTTGCTTCGCACTGAAAATTTGAAGTTATGAAAAAGGGAGTCGATGAGACTCCCTTTTTTTATTTATGGATTGGGTTG
TGGTTGAGGCTCGGGCTGGG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MSEPKDQQGVEVAKKRTRTAKSTSEDTSAPAAEASPAPAAEAAPAAPAPSENAPVSAAPAAAPEARQDRPQQQNQQRREF
RPHNRDNRDRGDRNDRGDRNDRGDRNDRGGHRGDRGNNQRRDFRHDRGRDEAQPMGDDAHSAMPAQVQDVDLADISLTDE
EKSWLSSKDLKSKNITQLTELANKLKIENAAGLRRQDMIFEILKRAAKLGQDIYGSGVLEILPDGYGFLRSPDYNYLPGP
DDIYVSPSQIRRFGLRTGDTVTGTVRPPKDGERYFALLKVDSLNFETTEKGKDKILFDNLTPLYPNERLKLEHNPGEYTT
RVVDLMAPLGKGQRALIVAPPRTGKTVLMQQIANAITHNHPEVKLIVLLIDERPEEVTDMQRTVKGEVVSSTFDEPPTRH
VQVAEMVIEKAKRLVEHKHDVVILLDSITRLARAYNTVVPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIATA
LIDTGSRMDEVIFEEFKGTGNAEIHLDRKLMEKRIFPCMDINKSGTRKEDLLVDKADLNRLWILRKVLAPMNVIDAMEFL
IDKVEGTKTNNDFLKAMSGPG

Sequences:

>Translated_581_residues
MSEPKDQQGVEVAKKRTRTAKSTSEDTSAPAAEASPAPAAEAAPAAPAPSENAPVSAAPAAAPEARQDRPQQQNQQRREF
RPHNRDNRDRGDRNDRGDRNDRGDRNDRGGHRGDRGNNQRRDFRHDRGRDEAQPMGDDAHSAMPAQVQDVDLADISLTDE
EKSWLSSKDLKSKNITQLTELANKLKIENAAGLRRQDMIFEILKRAAKLGQDIYGSGVLEILPDGYGFLRSPDYNYLPGP
DDIYVSPSQIRRFGLRTGDTVTGTVRPPKDGERYFALLKVDSLNFETTEKGKDKILFDNLTPLYPNERLKLEHNPGEYTT
RVVDLMAPLGKGQRALIVAPPRTGKTVLMQQIANAITHNHPEVKLIVLLIDERPEEVTDMQRTVKGEVVSSTFDEPPTRH
VQVAEMVIEKAKRLVEHKHDVVILLDSITRLARAYNTVVPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIATA
LIDTGSRMDEVIFEEFKGTGNAEIHLDRKLMEKRIFPCMDINKSGTRKEDLLVDKADLNRLWILRKVLAPMNVIDAMEFL
IDKVEGTKTNNDFLKAMSGPG
>Mature_580_residues
SEPKDQQGVEVAKKRTRTAKSTSEDTSAPAAEASPAPAAEAAPAAPAPSENAPVSAAPAAAPEARQDRPQQQNQQRREFR
PHNRDNRDRGDRNDRGDRNDRGDRNDRGGHRGDRGNNQRRDFRHDRGRDEAQPMGDDAHSAMPAQVQDVDLADISLTDEE
KSWLSSKDLKSKNITQLTELANKLKIENAAGLRRQDMIFEILKRAAKLGQDIYGSGVLEILPDGYGFLRSPDYNYLPGPD
DIYVSPSQIRRFGLRTGDTVTGTVRPPKDGERYFALLKVDSLNFETTEKGKDKILFDNLTPLYPNERLKLEHNPGEYTTR
VVDLMAPLGKGQRALIVAPPRTGKTVLMQQIANAITHNHPEVKLIVLLIDERPEEVTDMQRTVKGEVVSSTFDEPPTRHV
QVAEMVIEKAKRLVEHKHDVVILLDSITRLARAYNTVVPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIATAL
IDTGSRMDEVIFEEFKGTGNAEIHLDRKLMEKRIFPCMDINKSGTRKEDLLVDKADLNRLWILRKVLAPMNVIDAMEFLI
DKVEGTKTNNDFLKAMSGPG

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=412, Percent_Identity=68.4466019417476, Blast_Score=602, Evalue=1e-173,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 64656; Mature: 64525

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPKDQQGVEVAKKRTRTAKSTSEDTSAPAAEASPAPAAEAAPAAPAPSENAPVSAAPA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAPEARQDRPQQQNQQRREFRPHNRDNRDRGDRNDRGDRNDRGDRNDRGGHRGDRGNNQR
CCCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
RDFRHDRGRDEAQPMGDDAHSAMPAQVQDVDLADISLTDEEKSWLSSKDLKSKNITQLTE
HHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHH
LANKLKIENAAGLRRQDMIFEILKRAAKLGQDIYGSGVLEILPDGYGFLRSPDYNYLPGP
HHHHHCCCHHCCCHHHHHHHHHHHHHHHHCHHHHCCCCEEECCCCCCCCCCCCCCCCCCC
DDIYVSPSQIRRFGLRTGDTVTGTVRPPKDGERYFALLKVDSLNFETTEKGKDKILFDNL
CCEEECHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCC
TPLYPNERLKLEHNPGEYTTRVVDLMAPLGKGQRALIVAPPRTGKTVLMQQIANAITHNH
CCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
PEVKLIVLLIDERPEEVTDMQRTVKGEVVSSTFDEPPTRHVQVAEMVIEKAKRLVEHKHD
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
VVILLDSITRLARAYNTVVPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIATA
EEEEHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHCHHHHHHHHCCCCCCCCEEEEEEE
LIDTGSRMDEVIFEEFKGTGNAEIHLDRKLMEKRIFPCMDINKSGTRKEDLLVDKADLNR
HHHCCCHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCCCCCCCCCCHHHHEEEHHHHHH
LWILRKVLAPMNVIDAMEFLIDKVEGTKTNNDFLKAMSGPG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
SEPKDQQGVEVAKKRTRTAKSTSEDTSAPAAEASPAPAAEAAPAAPAPSENAPVSAAPA
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAPEARQDRPQQQNQQRREFRPHNRDNRDRGDRNDRGDRNDRGDRNDRGGHRGDRGNNQR
CCCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
RDFRHDRGRDEAQPMGDDAHSAMPAQVQDVDLADISLTDEEKSWLSSKDLKSKNITQLTE
HHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHH
LANKLKIENAAGLRRQDMIFEILKRAAKLGQDIYGSGVLEILPDGYGFLRSPDYNYLPGP
HHHHHCCCHHCCCHHHHHHHHHHHHHHHHCHHHHCCCCEEECCCCCCCCCCCCCCCCCCC
DDIYVSPSQIRRFGLRTGDTVTGTVRPPKDGERYFALLKVDSLNFETTEKGKDKILFDNL
CCEEECHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCC
TPLYPNERLKLEHNPGEYTTRVVDLMAPLGKGQRALIVAPPRTGKTVLMQQIANAITHNH
CCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
PEVKLIVLLIDERPEEVTDMQRTVKGEVVSSTFDEPPTRHVQVAEMVIEKAKRLVEHKHD
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
VVILLDSITRLARAYNTVVPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIATA
EEEEHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHCHHHHHHHHCCCCCCCCEEEEEEE
LIDTGSRMDEVIFEEFKGTGNAEIHLDRKLMEKRIFPCMDINKSGTRKEDLLVDKADLNR
HHHCCCHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCCCCCCCCCCHHHHEEEHHHHHH
LWILRKVLAPMNVIDAMEFLIDKVEGTKTNNDFLKAMSGPG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]