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The map label for this gene is ftsK [H]

Identifier: 42521689

GI number: 42521689

Start: 36142

End: 38535

Strand: Direct

Name: ftsK [H]

Synonym: Bd0041

Alternate gene names: 42521689

Gene position: 36142-38535 (Clockwise)

Preceding gene: 42521683

Following gene: 42521690

Centisome position: 0.96

GC content: 51.29

Gene sequence:

>2394_bases
ATGAACCAATTCCTTAAAAAGTTTCGACAGGACGTCATTTCAATAGGCTTTTTAGGCTTGGGGCTTTTCCTCGCCCTGGC
CCTTGTTAGCTACAACCCTATGGACCCTTCCCTAAATTCCATGGGACAGGGCCTAAGATCCACAAATTACTGCGGAATTG
TCGGAAGCTTCCTGGCGGATATGCTGTATCAGGCGATGGGCCTGGCGGCCTGGGTTGTGGTGGCCTGTTTTGGCAAAATC
GCCTATGCCAGCTTCAAGGGTGAATCCCTGAACCTAAAAAACATTCGTTTTGTCTGGGCTTTGCTGCTGATCGTGAACGT
GGCGGCTTTGTTCAGTCTGTATCTGCCCAACACCAAGATCTTCCAGGGGCAGATCTATCTGGGGGGCCTTTTGGGTTTGG
GCGTGTCCCAGGCGCTGATGCAGGCGTTTAACTCCGTGGGTGTGCAGGTGATTTTGTGGTCTTTGATGGCCGTGCTGGTG
GTGTTCTATTCCGAACGCACGCTGCAGGAACTGGCAGAGATTCCCCAGGGTCTTTTTGCTGACATGAAAAAGAAAAAGTT
CACCGACAAAATTGCGGCGTTCTTTTCTGGCATGTTCGTGAAGGAAGAAAAAACCAAGAAGTCCAAGAAAGACGAAAAAG
CCAAAGCGGCGATCTTCCCTCTTTCCGATAAAAAATTCGTAGAAAAAGCATCTGAAGAAGAGGAAGAGGACGAGGAGCTG
GAAGAGCTTCTGGCCGCGGCCGAAGAAGAGGATGAAGAAGAAGTCGAAGAAGACGAGGAAGAATCCGACGACGATGAAGA
GGAAGAAGTTCCTGCTGTTCGTCTGGCGCAAAAACGCAAAGTCGTGATGAAAGCCAAGCCTCCGCGTCGTATTGAAAACT
GGGATATGCCGAAATTGGCGTTGTTGGAAGATCCTCCAGCATCCCGAATCAAGATCGACAAGGCCGAGATTCAGCGCAAG
GCCGATTCACTGGTTGAAAAATTGAAGAACTTCTCCATCGAAGGCAGCATCCAGGACGCCAAACCCGGCCCGCTGGTCAC
GATGTATGAATTTAAACCCAATGCCGATGTGAAGATCTCAAAAATCTCAGAACTGGAAGACGATCTGTCTTTGGCATTGT
CTTCAGAATCCGTGCGTGTGGTGGGTCACATCCCGGGCACTGATGTTGTGGGTATTGAAACCGCGAACTTAAAGCGTGAA
ACCGTTTATTACAAAGACTTGATCGCGGAAGACACCTTCTGGAGCGAAGATCTGGCACTGCCGATGGCCGTGGGCCGTGC
GGTGGATGGGGAACCAAAAGTTGTGGATCTGAGAAAGATGCCGCACTTGCTGATCGCCGGGACGACGGGTTCTGGTAAGT
CCGTGTTCGTGGGCTCGATCATCACGGGTCTGTTGTTCAGACACTCACCGAAAACGCTGCGTTTGGTGCTGATTGACCCG
AAAATGGTCGACTTAGCACCATTCTCGACCGTTCCGCATCTGGTGCTTCCGCATGTGACCGAGCCGAAGAAGGCTGCGAC
TGCGCTGAAGTGGGCGGTGCGTGAGATGGAAAAACGTTATAAGTCCCTGTCGAAATTCGGTGTGGGTAAAATTGAAGCCT
TCAACGAAAAGACCGGCAATCTTTCCAAGGCCGACGTGGAAGAGCACGAAAAGATCAATCAGGATCTGGAAGAAGGCAAA
GCGAAGCTGGATCAGTACTATTACCAGCCACTGCCTTATATCGTGATCGTGGTGGATGAGTTGGCCGACTTGATGATCGT
TGAAAAACAAAACATTGAAGAGCCGATCCAGCGTCTGACGCAAAAAGCCCGTGCCTGCGGAATCCATTTGATTCTGGCGA
CACAGTCTCCGCGTAAAGACGTTGTGACCGGTTTGATTAAAACGAACATCCCAGGCCGAGTGGCTTTGAAAGTGGCGTCC
AAGATGGATTCCCGTATCATCATCGATGACTCGGGCGCTGAACGTCTGCTGCCAAACGGGGATATGCTGTTCCAGGCGCC
GGGTGTGGGAAAACCAACTCGTCACCATGGTCCTTATTTGTCAGACGCCGAAATCGGCAATGTCGTGAAACACTGGGCAT
CGCAGGCAGAGCCGGAATACGATCCACTGGCGATGAAAGCCCTGGATGGATTTGCTGGCGGTGATGGCGGCGAAGCTGGT
GGCGGCGACGGCGGCGGCTTTGGTGAAGAAGAGTATGATGAAAGATACGACGAGATTCTGTCTTGGGCTTCTGAGCAGAA
AGAAATCTCTGCGTCTTTAATTCAGCGCAAATTCAGACTCGGTTATCCGCGTGCCGCCCGCATGATTGAGATCTTCGAAA
AAGAAGGTGTTGTGGGGCCAGCGAATGGCAGCAAGCCGCGTCAAGTTCTTGTGAGTAGTTACAGAGAACAATAA

Upstream 100 bases:

>100_bases
TTAAGCATTTGACTGGCTCTTTGTCGGGCATACCGGGGCTTAAGTCAAGGAAGGCCCCGGGGAGCATGACTAACTGCTGG
GAATTTCGTAAATTTTTTAA

Downstream 100 bases:

>100_bases
ATAGAGTCTTGACTGCACCACCCTTGGTCGTGGTCTCATTAGGAGACCATATAACCATTCAAGGAGGAATTTATGTTCAA
GGCTCTTATTGCGGCCCTAG

Product: cell division protein FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MNQFLKKFRQDVISIGFLGLGLFLALALVSYNPMDPSLNSMGQGLRSTNYCGIVGSFLADMLYQAMGLAAWVVVACFGKI
AYASFKGESLNLKNIRFVWALLLIVNVAALFSLYLPNTKIFQGQIYLGGLLGLGVSQALMQAFNSVGVQVILWSLMAVLV
VFYSERTLQELAEIPQGLFADMKKKKFTDKIAAFFSGMFVKEEKTKKSKKDEKAKAAIFPLSDKKFVEKASEEEEEDEEL
EELLAAAEEEDEEEVEEDEEESDDDEEEEVPAVRLAQKRKVVMKAKPPRRIENWDMPKLALLEDPPASRIKIDKAEIQRK
ADSLVEKLKNFSIEGSIQDAKPGPLVTMYEFKPNADVKISKISELEDDLSLALSSESVRVVGHIPGTDVVGIETANLKRE
TVYYKDLIAEDTFWSEDLALPMAVGRAVDGEPKVVDLRKMPHLLIAGTTGSGKSVFVGSIITGLLFRHSPKTLRLVLIDP
KMVDLAPFSTVPHLVLPHVTEPKKAATALKWAVREMEKRYKSLSKFGVGKIEAFNEKTGNLSKADVEEHEKINQDLEEGK
AKLDQYYYQPLPYIVIVVDELADLMIVEKQNIEEPIQRLTQKARACGIHLILATQSPRKDVVTGLIKTNIPGRVALKVAS
KMDSRIIIDDSGAERLLPNGDMLFQAPGVGKPTRHHGPYLSDAEIGNVVKHWASQAEPEYDPLAMKALDGFAGGDGGEAG
GGDGGGFGEEEYDERYDEILSWASEQKEISASLIQRKFRLGYPRAARMIEIFEKEGVVGPANGSKPRQVLVSSYREQ

Sequences:

>Translated_797_residues
MNQFLKKFRQDVISIGFLGLGLFLALALVSYNPMDPSLNSMGQGLRSTNYCGIVGSFLADMLYQAMGLAAWVVVACFGKI
AYASFKGESLNLKNIRFVWALLLIVNVAALFSLYLPNTKIFQGQIYLGGLLGLGVSQALMQAFNSVGVQVILWSLMAVLV
VFYSERTLQELAEIPQGLFADMKKKKFTDKIAAFFSGMFVKEEKTKKSKKDEKAKAAIFPLSDKKFVEKASEEEEEDEEL
EELLAAAEEEDEEEVEEDEEESDDDEEEEVPAVRLAQKRKVVMKAKPPRRIENWDMPKLALLEDPPASRIKIDKAEIQRK
ADSLVEKLKNFSIEGSIQDAKPGPLVTMYEFKPNADVKISKISELEDDLSLALSSESVRVVGHIPGTDVVGIETANLKRE
TVYYKDLIAEDTFWSEDLALPMAVGRAVDGEPKVVDLRKMPHLLIAGTTGSGKSVFVGSIITGLLFRHSPKTLRLVLIDP
KMVDLAPFSTVPHLVLPHVTEPKKAATALKWAVREMEKRYKSLSKFGVGKIEAFNEKTGNLSKADVEEHEKINQDLEEGK
AKLDQYYYQPLPYIVIVVDELADLMIVEKQNIEEPIQRLTQKARACGIHLILATQSPRKDVVTGLIKTNIPGRVALKVAS
KMDSRIIIDDSGAERLLPNGDMLFQAPGVGKPTRHHGPYLSDAEIGNVVKHWASQAEPEYDPLAMKALDGFAGGDGGEAG
GGDGGGFGEEEYDERYDEILSWASEQKEISASLIQRKFRLGYPRAARMIEIFEKEGVVGPANGSKPRQVLVSSYREQ
>Mature_797_residues
MNQFLKKFRQDVISIGFLGLGLFLALALVSYNPMDPSLNSMGQGLRSTNYCGIVGSFLADMLYQAMGLAAWVVVACFGKI
AYASFKGESLNLKNIRFVWALLLIVNVAALFSLYLPNTKIFQGQIYLGGLLGLGVSQALMQAFNSVGVQVILWSLMAVLV
VFYSERTLQELAEIPQGLFADMKKKKFTDKIAAFFSGMFVKEEKTKKSKKDEKAKAAIFPLSDKKFVEKASEEEEEDEEL
EELLAAAEEEDEEEVEEDEEESDDDEEEEVPAVRLAQKRKVVMKAKPPRRIENWDMPKLALLEDPPASRIKIDKAEIQRK
ADSLVEKLKNFSIEGSIQDAKPGPLVTMYEFKPNADVKISKISELEDDLSLALSSESVRVVGHIPGTDVVGIETANLKRE
TVYYKDLIAEDTFWSEDLALPMAVGRAVDGEPKVVDLRKMPHLLIAGTTGSGKSVFVGSIITGLLFRHSPKTLRLVLIDP
KMVDLAPFSTVPHLVLPHVTEPKKAATALKWAVREMEKRYKSLSKFGVGKIEAFNEKTGNLSKADVEEHEKINQDLEEGK
AKLDQYYYQPLPYIVIVVDELADLMIVEKQNIEEPIQRLTQKARACGIHLILATQSPRKDVVTGLIKTNIPGRVALKVAS
KMDSRIIIDDSGAERLLPNGDMLFQAPGVGKPTRHHGPYLSDAEIGNVVKHWASQAEPEYDPLAMKALDGFAGGDGGEAG
GGDGGGFGEEEYDERYDEILSWASEQKEISASLIQRKFRLGYPRAARMIEIFEKEGVVGPANGSKPRQVLVSSYREQ

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=496, Percent_Identity=42.1370967741936, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 88340; Mature: 88340

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFLKKFRQDVISIGFLGLGLFLALALVSYNPMDPSLNSMGQGLRSTNYCGIVGSFLAD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHH
MLYQAMGLAAWVVVACFGKIAYASFKGESLNLKNIRFVWALLLIVNVAALFSLYLPNTKI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
FQGQIYLGGLLGLGVSQALMQAFNSVGVQVILWSLMAVLVVFYSERTLQELAEIPQGLFA
EECEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMKKKKFTDKIAAFFSGMFVKEEKTKKSKKDEKAKAAIFPLSDKKFVEKASEEEEEDEEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCCHHHHHH
EELLAAAEEEDEEEVEEDEEESDDDEEEEVPAVRLAQKRKVVMKAKPPRRIENWDMPKLA
HHHHHHHCCCCHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
LLEDPPASRIKIDKAEIQRKADSLVEKLKNFSIEGSIQDAKPGPLVTMYEFKPNADVKIS
EECCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEH
KISELEDDLSLALSSESVRVVGHIPGTDVVGIETANLKRETVYYKDLIAEDTFWSEDLAL
HHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCH
PMAVGRAVDGEPKVVDLRKMPHLLIAGTTGSGKSVFVGSIITGLLFRHSPKTLRLVLIDP
HHHHCCCCCCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECC
KMVDLAPFSTVPHLVLPHVTEPKKAATALKWAVREMEKRYKSLSKFGVGKIEAFNEKTGN
CEECCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
LSKADVEEHEKINQDLEEGKAKLDQYYYQPLPYIVIVVDELADLMIVEKQNIEEPIQRLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHH
QKARACGIHLILATQSPRKDVVTGLIKTNIPGRVALKVASKMDSRIIIDDSGAERLLPNG
HHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCC
DMLFQAPGVGKPTRHHGPYLSDAEIGNVVKHWASQAEPEYDPLAMKALDGFAGGDGGEAG
CEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCC
GGDGGGFGEEEYDERYDEILSWASEQKEISASLIQRKFRLGYPRAARMIEIFEKEGVVGP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
ANGSKPRQVLVSSYREQ
CCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNQFLKKFRQDVISIGFLGLGLFLALALVSYNPMDPSLNSMGQGLRSTNYCGIVGSFLAD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHH
MLYQAMGLAAWVVVACFGKIAYASFKGESLNLKNIRFVWALLLIVNVAALFSLYLPNTKI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
FQGQIYLGGLLGLGVSQALMQAFNSVGVQVILWSLMAVLVVFYSERTLQELAEIPQGLFA
EECEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMKKKKFTDKIAAFFSGMFVKEEKTKKSKKDEKAKAAIFPLSDKKFVEKASEEEEEDEEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCCHHHHHH
EELLAAAEEEDEEEVEEDEEESDDDEEEEVPAVRLAQKRKVVMKAKPPRRIENWDMPKLA
HHHHHHHCCCCHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
LLEDPPASRIKIDKAEIQRKADSLVEKLKNFSIEGSIQDAKPGPLVTMYEFKPNADVKIS
EECCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEH
KISELEDDLSLALSSESVRVVGHIPGTDVVGIETANLKRETVYYKDLIAEDTFWSEDLAL
HHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCH
PMAVGRAVDGEPKVVDLRKMPHLLIAGTTGSGKSVFVGSIITGLLFRHSPKTLRLVLIDP
HHHHCCCCCCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECC
KMVDLAPFSTVPHLVLPHVTEPKKAATALKWAVREMEKRYKSLSKFGVGKIEAFNEKTGN
CEECCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
LSKADVEEHEKINQDLEEGKAKLDQYYYQPLPYIVIVVDELADLMIVEKQNIEEPIQRLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHH
QKARACGIHLILATQSPRKDVVTGLIKTNIPGRVALKVASKMDSRIIIDDSGAERLLPNG
HHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCC
DMLFQAPGVGKPTRHHGPYLSDAEIGNVVKHWASQAEPEYDPLAMKALDGFAGGDGGEAG
CEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCC
GGDGGGFGEEEYDERYDEILSWASEQKEISASLIQRKFRLGYPRAARMIEIFEKEGVVGP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
ANGSKPRQVLVSSYREQ
CCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA