Click here to switch to the map view.

The map label for this gene is sdhB [H]

Identifier: 42521674

GI number: 42521674

Start: 24349

End: 25137

Strand: Direct

Name: sdhB [H]

Synonym: Bd0026

Alternate gene names: 42521674

Gene position: 24349-25137 (Clockwise)

Preceding gene: 42521673

Following gene: 42521675

Centisome position: 0.64

GC content: 52.85

Gene sequence:

>789_bases
ATGTCTGGAAAAAATATTAATCTGACTTTGAAAGTTTGGAGACAAAAAGGCCCGAAAGACCAGGGGGCCTTTGCAGAGTA
TCAGGCCAAGAACGTTTCTGAAGACGCTTCTTTCCTGGAAATGCTGGATGCTGTGAACGAAGAGCTGGTTGCAAAAGGTG
ATGAGCCTATCGCCTTTGACCACGACTGCCGTGAAGGTATCTGTGGTACTTGTGGTTTTGTGATCGACGGTGAAGCCCAC
GGTCCGATGAAATCCACAACTGTGTGTCAGCTGCACATGCGTAATTTCAACGACGGTGCGGTTCTGACAATTGAGCCTTT
CCGTGCAAAAGCCTTCCCGATGATCAAGGACTTGATGGTGGACAGATCCGCTTTGGATCGTATCATCTCTTCCGGTGGTT
ATATCTCTGCGAACACCGGTAACGCGGTTGACGCCAATGCGATTCTGGTTCCGAAGGCCGATGCGGATGAGGCGATGTCT
TCTGCAACGTGCATCGGTTGTGGCGCATGTGTGGCGGCTTGTAAGAACGCCTCTGCGGCCCTGTTCACTTCCGCGAAGAT
CTCTCACATGGCACTGCTTCCGCAGGGTCAGGTTGAAAGAAAAGAACGCGCCATGCGCATGGTGGGTGCGATGGATGCAG
AAGGCTTCGGTGCCTGCACCACAACAGGTGCGTGCGAAGCAGCCTGCCCGAAAGAAATCCAGCTGACCAACATCAGCCGC
ATGAACCGCGAATTCTTCGTGGCCAACGTCACCAAACGTGAAAAACACAAAGACGGCGGCGCCGGCTAA

Upstream 100 bases:

>100_bases
GAATACACTGGCGAAAACAAACCGTCCGTGCGTCACCAGGAAGAGCTGAAATTCGAAAACGTACACCTAGCAACTCGTAG
CTATAAATAAGAGGCGTAGC

Downstream 100 bases:

>100_bases
ATCTTCAAAGGGAGTCTTCGGACTCCCTTTTTTATTTCCAAAAGGTGCCTGGTGACTTTTTACACCTACGGCGCGTTAAG
TCCCCCTAAACACGGCTATT

Product: succinate dehydrogenase/fumarate reductase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSGKNINLTLKVWRQKGPKDQGAFAEYQAKNVSEDASFLEMLDAVNEELVAKGDEPIAFDHDCREGICGTCGFVIDGEAH
GPMKSTTVCQLHMRNFNDGAVLTIEPFRAKAFPMIKDLMVDRSALDRIISSGGYISANTGNAVDANAILVPKADADEAMS
SATCIGCGACVAACKNASAALFTSAKISHMALLPQGQVERKERAMRMVGAMDAEGFGACTTTGACEAACPKEIQLTNISR
MNREFFVANVTKREKHKDGGAG

Sequences:

>Translated_262_residues
MSGKNINLTLKVWRQKGPKDQGAFAEYQAKNVSEDASFLEMLDAVNEELVAKGDEPIAFDHDCREGICGTCGFVIDGEAH
GPMKSTTVCQLHMRNFNDGAVLTIEPFRAKAFPMIKDLMVDRSALDRIISSGGYISANTGNAVDANAILVPKADADEAMS
SATCIGCGACVAACKNASAALFTSAKISHMALLPQGQVERKERAMRMVGAMDAEGFGACTTTGACEAACPKEIQLTNISR
MNREFFVANVTKREKHKDGGAG
>Mature_261_residues
SGKNINLTLKVWRQKGPKDQGAFAEYQAKNVSEDASFLEMLDAVNEELVAKGDEPIAFDHDCREGICGTCGFVIDGEAHG
PMKSTTVCQLHMRNFNDGAVLTIEPFRAKAFPMIKDLMVDRSALDRIISSGGYISANTGNAVDANAILVPKADADEAMSS
ATCIGCGACVAACKNASAALFTSAKISHMALLPQGQVERKERAMRMVGAMDAEGFGACTTTGACEAACPKEIQLTNISRM
NREFFVANVTKREKHKDGGAG

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790596, Length=230, Percent_Identity=23.9130434782609, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 27922; Mature: 27791

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
8.8 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKNINLTLKVWRQKGPKDQGAFAEYQAKNVSEDASFLEMLDAVNEELVAKGDEPIAFD
CCCCCEEEEEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEC
HDCREGICGTCGFVIDGEAHGPMKSTTVCQLHMRNFNDGAVLTIEPFRAKAFPMIKDLMV
CHHHCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHH
DRSALDRIISSGGYISANTGNAVDANAILVPKADADEAMSSATCIGCGACVAACKNASAA
CHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHCCCCEE
LFTSAKISHMALLPQGQVERKERAMRMVGAMDAEGFGACTTTGACEAACPKEIQLTNISR
EEECCCHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCHHH
MNREFFVANVTKREKHKDGGAG
CCCEEEEEECHHHHHCCCCCCC
>Mature Secondary Structure 
SGKNINLTLKVWRQKGPKDQGAFAEYQAKNVSEDASFLEMLDAVNEELVAKGDEPIAFD
CCCCEEEEEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEC
HDCREGICGTCGFVIDGEAHGPMKSTTVCQLHMRNFNDGAVLTIEPFRAKAFPMIKDLMV
CHHHCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHH
DRSALDRIISSGGYISANTGNAVDANAILVPKADADEAMSSATCIGCGACVAACKNASAA
CHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHCCCCEE
LFTSAKISHMALLPQGQVERKERAMRMVGAMDAEGFGACTTTGACEAACPKEIQLTNISR
EEECCCHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCHHH
MNREFFVANVTKREKHKDGGAG
CCCEEEEEECHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]