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The map label for this gene is atpB

Identifier: 42521659

GI number: 42521659

Start: 10271

End: 10960

Strand: Direct

Name: atpB

Synonym: Bd0009

Alternate gene names: 42521659

Gene position: 10271-10960 (Clockwise)

Preceding gene: 42521658

Following gene: 42521660

Centisome position: 0.27

GC content: 48.12

Gene sequence:

>690_bases
ATGTCATTTAACTGGACACAATTGGTTCCGGGTGTTGGTCACGAGTACGCACACGTTGCGACTCTGGGTATTGCCACTGT
AGCAGCAGTAGGTATCGGTGCAGCTGCACGTGCTTCTCTGGGTAAAGGTGAAGCCGCTGTATTGCCAGCAAGCAAGTTCT
CTTTGCGTGGTATCTTCGAGCTTTTGACTGAGATGACTTCCGGTCTGGCTGACATGGTGATCGGCGAGCACGGCAAACAC
TACATCCCGTTCTTTGCTTCCGTGTTCTTCTTCATCTTGTTCAACAACTTGTTGGGCATGATCCCGGGTATGACTCCGGC
GACTGAAAACATGAACACCACATTCGGTTTCGGTGTGTTGATGTTCTTGTTCTATAACTTCCAGGGTGTAAAAGAAAACG
GACCAGTTGCTTACCTTAAGCACTTCATGGGTCCGGTGATCTTCCTGGCTCCATTGATGTTTGTGATCGAGATCGTTTCC
CACATCGTTCGCCCATTCTCTTTGGGTCTTCGTCTAGCGAACGTAATGATGGGTGACCACACGGTTCTTTCCGTGTTCCT
TGATCTGGTTCCAATCGGTGTACCAATTCCATTCTACGTGATGGGATTGTTCGTATGCTTTGTTCAGGCTTTTGTATTTA
CTTTGCTTTCAATGGTCTACGTGGCATTCGCGATTGCACACGATCACTAA

Upstream 100 bases:

>100_bases
ACTTGGTTCGACACTTTGTGGTTCGCACTAGGGGTCGCAAGTTTTATTCTTTCAGCGCTGGGATATGCGGTGAAAGAAGC
CTTAAGAGAAGGAAAAGAAG

Downstream 100 bases:

>100_bases
AAGGCAAATTTTTAAACCATAAGGAGTTCCACATGAAAAAAATGATCATCGCAGCTATCGCTATGTTCGCATCTTCTTCC
GCTTTCGCTCAAGAAGCAGC

Product: ATP synthase F0, A subunit

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSFNWTQLVPGVGHEYAHVATLGIATVAAVGIGAAARASLGKGEAAVLPASKFSLRGIFELLTEMTSGLADMVIGEHGKH
YIPFFASVFFFILFNNLLGMIPGMTPATENMNTTFGFGVLMFLFYNFQGVKENGPVAYLKHFMGPVIFLAPLMFVIEIVS
HIVRPFSLGLRLANVMMGDHTVLSVFLDLVPIGVPIPFYVMGLFVCFVQAFVFTLLSMVYVAFAIAHDH

Sequences:

>Translated_229_residues
MSFNWTQLVPGVGHEYAHVATLGIATVAAVGIGAAARASLGKGEAAVLPASKFSLRGIFELLTEMTSGLADMVIGEHGKH
YIPFFASVFFFILFNNLLGMIPGMTPATENMNTTFGFGVLMFLFYNFQGVKENGPVAYLKHFMGPVIFLAPLMFVIEIVS
HIVRPFSLGLRLANVMMGDHTVLSVFLDLVPIGVPIPFYVMGLFVCFVQAFVFTLLSMVYVAFAIAHDH
>Mature_228_residues
SFNWTQLVPGVGHEYAHVATLGIATVAAVGIGAAARASLGKGEAAVLPASKFSLRGIFELLTEMTSGLADMVIGEHGKHY
IPFFASVFFFILFNNLLGMIPGMTPATENMNTTFGFGVLMFLFYNFQGVKENGPVAYLKHFMGPVIFLAPLMFVIEIVSH
IVRPFSLGLRLANVMMGDHTVLSVFLDLVPIGVPIPFYVMGLFVCFVQAFVFTLLSMVYVAFAIAHDH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_BDEBA (Q6MRR3)

Other databases:

- EMBL:   BX842646
- RefSeq:   NP_967039.1
- ProteinModelPortal:   Q6MRR3
- SMR:   Q6MRR3
- GeneID:   2734349
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd0009
- NMPDR:   fig|264462.1.peg.9
- HOGENOM:   HBG734175
- OMA:   PIEIIGH
- ProtClustDB:   CLSK2761486
- BioCyc:   BBAC264462:BD0009-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 24920; Mature: 24789

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xbe45754)-; HASH(0xbe45a78)-; HASH(0xb53782c)-; HASH(0xbe4570c)-; HASH(0xbe47ba4)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNWTQLVPGVGHEYAHVATLGIATVAAVGIGAAARASLGKGEAAVLPASKFSLRGIFE
CCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEECCCHHHHHHHHHH
LLTEMTSGLADMVIGEHGKHYIPFFASVFFFILFNNLLGMIPGMTPATENMNTTFGFGVL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
MFLFYNFQGVKENGPVAYLKHFMGPVIFLAPLMFVIEIVSHIVRPFSLGLRLANVMMGDH
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TVLSVFLDLVPIGVPIPFYVMGLFVCFVQAFVFTLLSMVYVAFAIAHDH
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SFNWTQLVPGVGHEYAHVATLGIATVAAVGIGAAARASLGKGEAAVLPASKFSLRGIFE
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEECCCHHHHHHHHHH
LLTEMTSGLADMVIGEHGKHYIPFFASVFFFILFNNLLGMIPGMTPATENMNTTFGFGVL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
MFLFYNFQGVKENGPVAYLKHFMGPVIFLAPLMFVIEIVSHIVRPFSLGLRLANVMMGDH
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TVLSVFLDLVPIGVPIPFYVMGLFVCFVQAFVFTLLSMVYVAFAIAHDH
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA