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The map label for this gene is muT4 [H]

Identifier: 41410432

GI number: 41410432

Start: 4811625

End: 4812374

Strand: Direct

Name: muT4 [H]

Synonym: MAP4334

Alternate gene names: 41410432

Gene position: 4811625-4812374 (Clockwise)

Preceding gene: 41410431

Following gene: 41410433

Centisome position: 99.62

GC content: 71.73

Gene sequence:

>750_bases
GTGTCGGACGGCGAACAAGGCAAACCACGTCGGCGCCGGGGGCGGCGCCGCGGCCGTGGTGCTGCAACGTCGTCGGAGAA
ACAGACCAACGGTCAACTGACCGGCGACTCGACCGCCACCAAGCCCCGCCGATCCCGTGCCGCGCGCCGCGCCCCGGATC
GGCTGCGCACCGTGCACGAAACCTCCGCCGGCGGCCTGGTCATCGACGGCCTGGACGGGCCGCGCGAATCACAGGTCGCC
GCCCTGATCGGGCGCATCGACCGGCGCGGCCGCATGCTGTGGTCGCTGCCCAAAGGGCACATCGAGCTGGGTGAGACCGC
CGAACAGACCGCGATCAGAGAAGTAGCCGAAGAGACCGGCATCCGGGGCAGCGTGCTGGCCGCGCTGGGCCGCATCGACT
ACTGGTTCGTCACCGACGGCCGGCGCGTGCACAAGACCGTGCACCACTATCTAATGCGCTTCTCCGGCGGGGAACTCTCC
GACGAGGACCTCGAGGTCGCTGAGGTCGCCTGGGTGCCGATGCGCGAGCTGCCGTCCCGGCTGGCCTACGCCGACGAACG
CCGGCTGGCCCGGGTCGCCGACGAGCTGATCGACAAGCTGCAAAGCGACGGCCCTGCCGCGCTTCCGCCGCTGCCGCCCA
GCTCCCCGCGCCGCCGCCCGCAGACGCATTCCCGGACGCGGCATTCGGAGACGCGGCATTCGGACAAACCGGCCACCGGC
CGGAAGAACGGCCACGGACCGGGGCCGTGA

Upstream 100 bases:

>100_bases
TAACCGAAGTCATGAGCTGGACACAGCGCAGGACTTGCCCACGCCCACCCAGCGGCGAGTATGTCCAGGAGAACATGCCG
TGCCAGCTACTATCGCTTGG

Downstream 100 bases:

>100_bases
CGGCGCCGCGTTTGTGTTGGGCCGGCGGGTTGCGCATCGCCGCCGTGCTCGGCGTCCTGGCCGGGCTTGCGGTGCTCACC
GGGCCGGTGACACCGCGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSDGEQGKPRRRRGRRRGRGAATSSEKQTNGQLTGDSTATKPRRSRAARRAPDRLRTVHETSAGGLVIDGLDGPRESQVA
ALIGRIDRRGRMLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWFVTDGRRVHKTVHHYLMRFSGGELS
DEDLEVAEVAWVPMRELPSRLAYADERRLARVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRTRHSETRHSDKPATG
RKNGHGPGP

Sequences:

>Translated_249_residues
MSDGEQGKPRRRRGRRRGRGAATSSEKQTNGQLTGDSTATKPRRSRAARRAPDRLRTVHETSAGGLVIDGLDGPRESQVA
ALIGRIDRRGRMLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWFVTDGRRVHKTVHHYLMRFSGGELS
DEDLEVAEVAWVPMRELPSRLAYADERRLARVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRTRHSETRHSDKPATG
RKNGHGPGP
>Mature_248_residues
SDGEQGKPRRRRGRRRGRGAATSSEKQTNGQLTGDSTATKPRRSRAARRAPDRLRTVHETSAGGLVIDGLDGPRESQVAA
LIGRIDRRGRMLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWFVTDGRRVHKTVHHYLMRFSGGELSD
EDLEVAEVAWVPMRELPSRLAYADERRLARVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRTRHSETRHSDKPATGR
KNGHGPGP

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 27568; Mature: 27437

Theoretical pI: Translated: 11.40; Mature: 11.40

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGEQGKPRRRRGRRRGRGAATSSEKQTNGQLTGDSTATKPRRSRAARRAPDRLRTVHE
CCCCCCCCHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHH
TSAGGLVIDGLDGPRESQVAALIGRIDRRGRMLWSLPKGHIELGETAEQTAIREVAEETG
CCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEECCCHHHHHHHHHHHHHHC
IRGSVLAALGRIDYWFVTDGRRVHKTVHHYLMRFSGGELSDEDLEVAEVAWVPMRELPSR
CCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHH
LAYADERRLARVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRTRHSETRHSDKPATG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
RKNGHGPGP
CCCCCCCCC
>Mature Secondary Structure 
SDGEQGKPRRRRGRRRGRGAATSSEKQTNGQLTGDSTATKPRRSRAARRAPDRLRTVHE
CCCCCCCHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHH
TSAGGLVIDGLDGPRESQVAALIGRIDRRGRMLWSLPKGHIELGETAEQTAIREVAEETG
CCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEECCCHHHHHHHHHHHHHHC
IRGSVLAALGRIDYWFVTDGRRVHKTVHHYLMRFSGGELSDEDLEVAEVAWVPMRELPSR
CCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHH
LAYADERRLARVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRTRHSETRHSDKPATG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
RKNGHGPGP
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]