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The map label for this gene is pkn1 [H]

Identifier: 41410272

GI number: 41410272

Start: 4648215

End: 4649105

Strand: Direct

Name: pkn1 [H]

Synonym: MAP4174

Alternate gene names: 41410272

Gene position: 4648215-4649105 (Clockwise)

Preceding gene: 41410271

Following gene: 41410273

Centisome position: 96.24

GC content: 71.94

Gene sequence:

>891_bases
GTGCGCAGCGAGCTGGCGGACCTGCCGGGCGGGTCGTTCCGGATGGGCTCGACGAGCTTCTATCCCGAAGAGGCGCCGAT
CCACACGGTGACGGTGGAGCCCTTCGCGATCGAACGCCACCCGGTGACCAACGCGCAGTTCGCCGAGTTCGTCGCCGCCA
CCGGCTACGTGACGGTGGCCGAGCAACCGATCGACCCGGCGCTGTACCCGGGCGCCGACCCGTCCCAATTACAGCCGGGT
GCAATGGTTTTCCGGCCCACACCGGGGCCGGTGGACCTGCGCGACTGGAGGCAGTGGTGGCACTGGGTGCCCGGGGCCAG
CTGGCGCCACCCTTTCGGGCCGGACAGCGACGTCGCCGATCGCGCCGACCATCCGGTGGTGCAGGTGGCCTACCCCGACG
CCGCGGCCTACGCCCGCTGGGCGGGGCGGCGGCTGCCCACCGAGGCCGAGTGGGAATACGCCGCCCGCGCAGGGGCCACC
ACCACCTACCCCTGGGGCGACGAGCCCACCAGCGACGGCCGGCTGATGGCCAACACCTGGCAGGGCCGCTTCCCGTACCG
CAACGACGGGGCGCTCGGCTGGGTGGGCACCTCGCCGGTCGGCGTCTTCGCGCCCAACGCGTTCGGCCTGCTCGACATGA
TCGGCAACGTCTGGGAGTGGACCACCACCGAGTTCTCCACCCATCACCGGATCGGGGCGGCGACCAAGCCCTGCTGCGCC
CCGTCGGGCCCCGCCGACCCGAGCGTCAACCAGACCTTGAAGGGCGGCAGCCATTTGTGCGCGCCGGAGTACTGCCACCG
CTACCGCCCGGCGGCGCGTTCGCCGCAGTCGCAGGACTCGGCGACCACCCACATCGGCTTTCGCTGCGTGGCCGAATTGG
GTTCGAACTAG

Upstream 100 bases:

>100_bases
CTCTGGGTGCTGATCGCGCTGGTGGCGTCGATGGTCCTGTTCCTGATCACCTGGTACCGGCGCACGGACTGAGTTCCCGT
CAGGGTCCTACCCTGGTGGG

Downstream 100 bases:

>100_bases
CAAACCCGGCGAGGCGTGAACGGCGGATGGCGGCACGGTGACGCCCACGTGATGCCTTGGTGGACAAGAGATTTCACCGC
GCGCCGGACCCCTGCGTTCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MRSELADLPGGSFRMGSTSFYPEEAPIHTVTVEPFAIERHPVTNAQFAEFVAATGYVTVAEQPIDPALYPGADPSQLQPG
AMVFRPTPGPVDLRDWRQWWHWVPGASWRHPFGPDSDVADRADHPVVQVAYPDAAAYARWAGRRLPTEAEWEYAARAGAT
TTYPWGDEPTSDGRLMANTWQGRFPYRNDGALGWVGTSPVGVFAPNAFGLLDMIGNVWEWTTTEFSTHHRIGAATKPCCA
PSGPADPSVNQTLKGGSHLCAPEYCHRYRPAARSPQSQDSATTHIGFRCVAELGSN

Sequences:

>Translated_296_residues
MRSELADLPGGSFRMGSTSFYPEEAPIHTVTVEPFAIERHPVTNAQFAEFVAATGYVTVAEQPIDPALYPGADPSQLQPG
AMVFRPTPGPVDLRDWRQWWHWVPGASWRHPFGPDSDVADRADHPVVQVAYPDAAAYARWAGRRLPTEAEWEYAARAGAT
TTYPWGDEPTSDGRLMANTWQGRFPYRNDGALGWVGTSPVGVFAPNAFGLLDMIGNVWEWTTTEFSTHHRIGAATKPCCA
PSGPADPSVNQTLKGGSHLCAPEYCHRYRPAARSPQSQDSATTHIGFRCVAELGSN
>Mature_296_residues
MRSELADLPGGSFRMGSTSFYPEEAPIHTVTVEPFAIERHPVTNAQFAEFVAATGYVTVAEQPIDPALYPGADPSQLQPG
AMVFRPTPGPVDLRDWRQWWHWVPGASWRHPFGPDSDVADRADHPVVQVAYPDAAAYARWAGRRLPTEAEWEYAARAGAT
TTYPWGDEPTSDGRLMANTWQGRFPYRNDGALGWVGTSPVGVFAPNAFGLLDMIGNVWEWTTTEFSTHHRIGAATKPCCA
PSGPADPSVNQTLKGGSHLCAPEYCHRYRPAARSPQSQDSATTHIGFRCVAELGSN

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=297, Percent_Identity=41.0774410774411, Blast_Score=227, Evalue=8e-60,
Organism=Homo sapiens, GI257470975, Length=295, Percent_Identity=40, Blast_Score=214, Evalue=8e-56,
Organism=Homo sapiens, GI257470977, Length=297, Percent_Identity=39.7306397306397, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI194248088, Length=300, Percent_Identity=36, Blast_Score=161, Evalue=6e-40,
Organism=Homo sapiens, GI194248087, Length=300, Percent_Identity=34, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI226437577, Length=202, Percent_Identity=39.1089108910891, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI194248090, Length=263, Percent_Identity=34.2205323193916, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI20130397, Length=291, Percent_Identity=38.4879725085911, Blast_Score=196, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 32365; Mature: 32365

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSELADLPGGSFRMGSTSFYPEEAPIHTVTVEPFAIERHPVTNAQFAEFVAATGYVTVA
CCCCCCCCCCCCEECCCCCCCCCCCCEEEEEECCEEECCCCCCCHHHHHHHHHCCEEEEE
EQPIDPALYPGADPSQLQPGAMVFRPTPGPVDLRDWRQWWHWVPGASWRHPFGPDSDVAD
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHH
RADHPVVQVAYPDAAAYARWAGRRLPTEAEWEYAARAGATTTYPWGDEPTSDGRLMANTW
CCCCCEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEEC
QGRFPYRNDGALGWVGTSPVGVFAPNAFGLLDMIGNVWEWTTTEFSTHHRIGAATKPCCA
CCCCCCCCCCCEEEECCCCCEEECCCHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCC
PSGPADPSVNQTLKGGSHLCAPEYCHRYRPAARSPQSQDSATTHIGFRCVAELGSN
CCCCCCCCHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSELADLPGGSFRMGSTSFYPEEAPIHTVTVEPFAIERHPVTNAQFAEFVAATGYVTVA
CCCCCCCCCCCCEECCCCCCCCCCCCEEEEEECCEEECCCCCCCHHHHHHHHHCCEEEEE
EQPIDPALYPGADPSQLQPGAMVFRPTPGPVDLRDWRQWWHWVPGASWRHPFGPDSDVAD
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHH
RADHPVVQVAYPDAAAYARWAGRRLPTEAEWEYAARAGATTTYPWGDEPTSDGRLMANTW
CCCCCEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEEC
QGRFPYRNDGALGWVGTSPVGVFAPNAFGLLDMIGNVWEWTTTEFSTHHRIGAATKPCCA
CCCCCCCCCCCEEEECCCCCEEECCCHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCC
PSGPADPSVNQTLKGGSHLCAPEYCHRYRPAARSPQSQDSATTHIGFRCVAELGSN
CCCCCCCCHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]