Click here to switch to the map view.

The map label for this gene is pqqE

Identifier: 41410251

GI number: 41410251

Start: 4630631

End: 4631845

Strand: Direct

Name: pqqE

Synonym: MAP4153

Alternate gene names: 41410251

Gene position: 4630631-4631845 (Clockwise)

Preceding gene: 41410250

Following gene: 41410252

Centisome position: 95.88

GC content: 70.86

Gene sequence:

>1215_bases
ATGACCACAGTGGCCCCTGTGCCCCGGCTGATCGAGCAGTTCGAGCACGGCCTCGACGCGCCCATCTGCTTGACCTGGGA
GCTCACCTACGCCTGCAACCTGGCCTGCGTGCACTGCCTGTCCTCGTCGGGCAAGCGCGACCCGCGCGAGCTGTCCACCC
GTCAGTGCATGGACATCATCGACGAGCTGGAACGCATGCAGGTCTTCTACGTCAACATCGGTGGCGGGGAACCGACTGTG
CGGCCGGACTTTTGGGAGTTGGTCGACTATGCGACCGCACACCACGTCGGCGTGAAGTTCTCCACCAACGGGGTCCGGAT
CACGCCCGAGGTGGCCGCCCGGCTGGCGGCCAGCGACTACGTGGACGTGCAGATCTCGCTGGACGGCGCCACCGCCGAGG
TCAACGACGCGGTGCGCGGGCCCGGCTCGTTCGACATGGCGGTGCGGGCGCTGCAGAACCTCGCCGACGCCGGCTTCACC
CAGAACGGGGGCGCCAAGATCTCGGTGGTCGTCACCCGGCACAACGTCGGGCAGCTGGACGAATTCGCCGCGCTGGCAAG
CCGTTACGGGGCCACACTGCGCATCACCCGGCTGCGCCCGTCCGGCCGCGGCGCCGACGTCTGGGACGAGCTGCACCCCA
CCGCCGACCAGCAGGTGCAACTGTATGACTGGCTGGTCGCCAAGGGGGAACGGGTGCTCACCGGCGACTCGTTCTTCCAC
CTGGCCCCGCTCGGCCAGTCCGGCGCGCTGGCCGGTCTGAACATGTGCGGCGCGGGCCGCGTCGTCTGCCTGATCGACCC
GGTCGGCGACGTGTACGCCTGCCCGTTCGCCATCCACGACCGCTTCCTGGCCGGAAACGTGTTGAGCGACGGCGGTTTTG
ACAACGTGTGGAAGAACGCCCCGCTGTTGCGCGAGCTGCGCGAACCGCAGTCGGCGGGCGCCTGCGGCAGCTGCGGGCAC
TACGACAGCTGCCGGGGCGGGTGCATGGCGGCCAAGTTCTTCACCGGCCTGCCGCTGGACGGCCCGGACCCCGAGTGCGT
GCAGGGCCACAGCGCGGCGGCGCTGGCGGGCGACCGCGAGGCGCCCCGACCCCGGGCCGACCATTCCCGCGGCAAGCGCA
TCCGCCAACCCGTGCCGCTCACCCTCTCGGTGCGGCCGCCGGTCCTGACCCCCGCCGCGCCGCCGGCCCGGTTGTGCAAC
GAAAGCCCGGTCTGA

Upstream 100 bases:

>100_bases
GCCGCGCGGCGGGCATCGACGACGCCGGGCAGGCGCCGTACCTGCACGCGCTGGGCGTGCTCGCCGACTCCAACATGCTG
GTGCCCCGGGAGGACCATCC

Downstream 100 bases:

>100_bases
CCGTGGCCGACGAATGGTTTGAAACCGTCGCCATCGCTCAGCAACGGGCCAAGCGGCGGTTGCCGAAATCCGTTTATGCG
GCCCTGATCGCGGCCAGCGA

Product: PqqE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTTVAPVPRLIEQFEHGLDAPICLTWELTYACNLACVHCLSSSGKRDPRELSTRQCMDIIDELERMQVFYVNIGGGEPTV
RPDFWELVDYATAHHVGVKFSTNGVRITPEVAARLAASDYVDVQISLDGATAEVNDAVRGPGSFDMAVRALQNLADAGFT
QNGGAKISVVVTRHNVGQLDEFAALASRYGATLRITRLRPSGRGADVWDELHPTADQQVQLYDWLVAKGERVLTGDSFFH
LAPLGQSGALAGLNMCGAGRVVCLIDPVGDVYACPFAIHDRFLAGNVLSDGGFDNVWKNAPLLRELREPQSAGACGSCGH
YDSCRGGCMAAKFFTGLPLDGPDPECVQGHSAAALAGDREAPRPRADHSRGKRIRQPVPLTLSVRPPVLTPAAPPARLCN
ESPV

Sequences:

>Translated_404_residues
MTTVAPVPRLIEQFEHGLDAPICLTWELTYACNLACVHCLSSSGKRDPRELSTRQCMDIIDELERMQVFYVNIGGGEPTV
RPDFWELVDYATAHHVGVKFSTNGVRITPEVAARLAASDYVDVQISLDGATAEVNDAVRGPGSFDMAVRALQNLADAGFT
QNGGAKISVVVTRHNVGQLDEFAALASRYGATLRITRLRPSGRGADVWDELHPTADQQVQLYDWLVAKGERVLTGDSFFH
LAPLGQSGALAGLNMCGAGRVVCLIDPVGDVYACPFAIHDRFLAGNVLSDGGFDNVWKNAPLLRELREPQSAGACGSCGH
YDSCRGGCMAAKFFTGLPLDGPDPECVQGHSAAALAGDREAPRPRADHSRGKRIRQPVPLTLSVRPPVLTPAAPPARLCN
ESPV
>Mature_403_residues
TTVAPVPRLIEQFEHGLDAPICLTWELTYACNLACVHCLSSSGKRDPRELSTRQCMDIIDELERMQVFYVNIGGGEPTVR
PDFWELVDYATAHHVGVKFSTNGVRITPEVAARLAASDYVDVQISLDGATAEVNDAVRGPGSFDMAVRALQNLADAGFTQ
NGGAKISVVVTRHNVGQLDEFAALASRYGATLRITRLRPSGRGADVWDELHPTADQQVQLYDWLVAKGERVLTGDSFFHL
APLGQSGALAGLNMCGAGRVVCLIDPVGDVYACPFAIHDRFLAGNVLSDGGFDNVWKNAPLLRELREPQSAGACGSCGHY
DSCRGGCMAAKFFTGLPLDGPDPECVQGHSAAALAGDREAPRPRADHSRGKRIRQPVPLTLSVRPPVLTPAAPPARLCNE
SPV

Specific function: Required for production of the bacteriocin subtilosin. May activate a metalloenzyme that catalyzes a modification of prosubtilosin [H]

COG id: COG0535

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786999, Length=213, Percent_Identity=25.8215962441315, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR008792
- InterPro:   IPR007197 [H]

Pfam domain/function: PF05402 PqqD; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 43382; Mature: 43250

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVAPVPRLIEQFEHGLDAPICLTWELTYACNLACVHCLSSSGKRDPRELSTRQCMDII
CCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DELERMQVFYVNIGGGEPTVRPDFWELVDYATAHHVGVKFSTNGVRITPEVAARLAASDY
HHHHCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHEEEEEECCCEEECHHHHHHHHCCCE
VDVQISLDGATAEVNDAVRGPGSFDMAVRALQNLADAGFTQNGGAKISVVVTRHNVGQLD
EEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHH
EFAALASRYGATLRITRLRPSGRGADVWDELHPTADQQVQLYDWLVAKGERVLTGDSFFH
HHHHHHHHCCCEEEEEEECCCCCCCCHHHHHCCCCCCCEEHHHHHHHCCCEEEECCCEEE
LAPLGQSGALAGLNMCGAGRVVCLIDPVGDVYACPFAIHDRFLAGNVLSDGGFDNVWKNA
EECCCCCCCCCCCEECCCCCEEEEECCCCCCEECCHHHHHHHHCCCCCCCCCCCHHHCCC
PLLRELREPQSAGACGSCGHYDSCRGGCMAAKFFTGLPLDGPDPECVQGHSAAALAGDRE
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHCCCCCCCCCHHHHCCCCCEEECCCCC
APRPRADHSRGKRIRQPVPLTLSVRPPVLTPAAPPARLCNESPV
CCCCCCCCHHCCHHCCCCCEEEECCCCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure 
TTVAPVPRLIEQFEHGLDAPICLTWELTYACNLACVHCLSSSGKRDPRELSTRQCMDII
CCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DELERMQVFYVNIGGGEPTVRPDFWELVDYATAHHVGVKFSTNGVRITPEVAARLAASDY
HHHHCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHEEEEEECCCEEECHHHHHHHHCCCE
VDVQISLDGATAEVNDAVRGPGSFDMAVRALQNLADAGFTQNGGAKISVVVTRHNVGQLD
EEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHH
EFAALASRYGATLRITRLRPSGRGADVWDELHPTADQQVQLYDWLVAKGERVLTGDSFFH
HHHHHHHHCCCEEEEEEECCCCCCCCHHHHHCCCCCCCEEHHHHHHHCCCEEEECCCEEE
LAPLGQSGALAGLNMCGAGRVVCLIDPVGDVYACPFAIHDRFLAGNVLSDGGFDNVWKNA
EECCCCCCCCCCCEECCCCCEEEEECCCCCCEECCHHHHHHHHCCCCCCCCCCCHHHCCC
PLLRELREPQSAGACGSCGHYDSCRGGCMAAKFFTGLPLDGPDPECVQGHSAAALAGDRE
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHCCCCCCCCCHHHHCCCCCEEECCCCC
APRPRADHSRGKRIRQPVPLTLSVRPPVLTPAAPPARLCNESPV
CCCCCCCCHHCCHHCCCCCEEEECCCCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 10572140; 10809709; 10809710 [H]