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The map label for this gene is grcC1

Identifier: 41410156

GI number: 41410156

Start: 4518442

End: 4519449

Strand: Direct

Name: grcC1

Synonym: MAP4058

Alternate gene names: 41410156

Gene position: 4518442-4519449 (Clockwise)

Preceding gene: 161611201

Following gene: 41410157

Centisome position: 93.55

GC content: 71.13

Gene sequence:

>1008_bases
GTGAATACTCCGGCGACGGTGGTGGCGGGCGTGGATTTCGGTGACCCGGCTTTCGCGGCGACCGTGCGCGACGGCGTCGG
GCGCATCGAGCAGCTCATGGACACCGAGCTGCGCAGCGCCGACGACATCATGACCGAGTCGCTGACCCATCTGTTCAAGG
CCGGCGGCAAGCGGTTCCGCCCGCTGTTCACCGTGCTGTCCGCGCAGATCGGCCCCGACCCCGACGCCGCCGAGGTGACC
ATCGCCGGCGCCGTCATCGAGCTGGTGCACCTGGCCACGCTCTACCACGACGACGTGATGGACGAGGCGGAGGTGCGCCG
CGGCACCCCCACCGCCAACGTGCGCTGGGGCAACAACGTCGCGATCCTGGCCGGGGACTATCTGTTCGCCACGGCGTCGC
GGCTGGTGTCGCGGCTGGGCCCGGAGGCGGTGCGGCTGATCGCCGAGACATTCGCCCAGCTGGTGACCGGGCAGATGCGC
GAGACCCGCGGCCGCAAGCAGGGATCGGACCCGATCGAGCACTACCTGAAGGTGGTGTACGAGAAGACGGCGTGCCTGAT
CGCCGCGGCGGGCCGGTTCGGGGCCATGTTCTCCGGGGCCGACGCCGACCAGGTCGAGCGGCTGAGCCGGCTGGGCGGCA
TCGTGGGCACCGCGTTCCAGATCTCCGACGACATCATCGACATCGACAGCGACTCGCACGAATCCGGCAAGCTGCCCGGC
ACCGACGTGCGCGAAGGCGTGCACACCCTGCCGATGGTCTACGCGCTGCGCGAACCCGGGCCGGACGCGGCGCGGCTGCG
CGAGTTGCTGGTCGGGCCGATCGACGACGACGAGGTGGTGGCCGAGGCGCTGACGCTGCTGCGGGCGTCGCCGGGCATGG
CCAAGGCCAAGCAGTCGCTGCGCGAGTACGCGGCGCAGGCGCATCGGGAGCTGGACCAGCTGCCCGACGTCCCGGGCCGG
CGCGCGCTGCAAACACTGGTCGACTTCACCATCAGCCGGCACGGCTAG

Upstream 100 bases:

>100_bases
GGCCCAGGCCGCCGCGGCGGATCCGGCGGGCCCGGCGCCCACCACCACCAGATCGGCTCGGGTCGCTGCCGTCGTCATGC
ACACCAGTATGTTTGGTCGG

Downstream 100 bases:

>100_bases
CGCGTCGCGGAACCAACCGGGCCGTCTCGAGCGTTCAATTAGCGCAAGTCAGCAAGAGCGCGTGTGTGCCCGTGCACTGC
GAGGAGGACAGCGATGACCT

Product: GrcC1

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNTPATVVAGVDFGDPAFAATVRDGVGRIEQLMDTELRSADDIMTESLTHLFKAGGKRFRPLFTVLSAQIGPDPDAAEVT
IAGAVIELVHLATLYHDDVMDEAEVRRGTPTANVRWGNNVAILAGDYLFATASRLVSRLGPEAVRLIAETFAQLVTGQMR
ETRGRKQGSDPIEHYLKVVYEKTACLIAAAGRFGAMFSGADADQVERLSRLGGIVGTAFQISDDIIDIDSDSHESGKLPG
TDVREGVHTLPMVYALREPGPDAARLRELLVGPIDDDEVVAEALTLLRASPGMAKAKQSLREYAAQAHRELDQLPDVPGR
RALQTLVDFTISRHG

Sequences:

>Translated_335_residues
MNTPATVVAGVDFGDPAFAATVRDGVGRIEQLMDTELRSADDIMTESLTHLFKAGGKRFRPLFTVLSAQIGPDPDAAEVT
IAGAVIELVHLATLYHDDVMDEAEVRRGTPTANVRWGNNVAILAGDYLFATASRLVSRLGPEAVRLIAETFAQLVTGQMR
ETRGRKQGSDPIEHYLKVVYEKTACLIAAAGRFGAMFSGADADQVERLSRLGGIVGTAFQISDDIIDIDSDSHESGKLPG
TDVREGVHTLPMVYALREPGPDAARLRELLVGPIDDDEVVAEALTLLRASPGMAKAKQSLREYAAQAHRELDQLPDVPGR
RALQTLVDFTISRHG
>Mature_335_residues
MNTPATVVAGVDFGDPAFAATVRDGVGRIEQLMDTELRSADDIMTESLTHLFKAGGKRFRPLFTVLSAQIGPDPDAAEVT
IAGAVIELVHLATLYHDDVMDEAEVRRGTPTANVRWGNNVAILAGDYLFATASRLVSRLGPEAVRLIAETFAQLVTGQMR
ETRGRKQGSDPIEHYLKVVYEKTACLIAAAGRFGAMFSGADADQVERLSRLGGIVGTAFQISDDIIDIDSDSHESGKLPG
TDVREGVHTLPMVYALREPGPDAARLRELLVGPIDDDEVVAEALTLLRASPGMAKAKQSLREYAAQAHRELDQLPDVPGR
RALQTLVDFTISRHG

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=335, Percent_Identity=30.1492537313433, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI4758430, Length=283, Percent_Identity=24.7349823321555, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI83700220, Length=283, Percent_Identity=24.7349823321555, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1789578, Length=299, Percent_Identity=31.7725752508361, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786623, Length=309, Percent_Identity=28.8025889967638, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17505681, Length=324, Percent_Identity=28.7037037037037, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6319475, Length=295, Percent_Identity=29.4915254237288, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6325188, Length=226, Percent_Identity=25.6637168141593, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24651612, Length=293, Percent_Identity=29.3515358361775, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI281365769, Length=300, Percent_Identity=27.3333333333333, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24660002, Length=300, Percent_Identity=27.3333333333333, Blast_Score=95, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 36139; Mature: 36139

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPATVVAGVDFGDPAFAATVRDGVGRIEQLMDTELRSADDIMTESLTHLFKAGGKRFR
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
PLFTVLSAQIGPDPDAAEVTIAGAVIELVHLATLYHDDVMDEAEVRRGTPTANVRWGNNV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEE
AILAGDYLFATASRLVSRLGPEAVRLIAETFAQLVTGQMRETRGRKQGSDPIEHYLKVVY
EEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EKTACLIAAAGRFGAMFSGADADQVERLSRLGGIVGTAFQISDDIIDIDSDSHESGKLPG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEECCCEEECCCCCCCCCCCCC
TDVREGVHTLPMVYALREPGPDAARLRELLVGPIDDDEVVAEALTLLRASPGMAKAKQSL
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
REYAAQAHRELDQLPDVPGRRALQTLVDFTISRHG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTPATVVAGVDFGDPAFAATVRDGVGRIEQLMDTELRSADDIMTESLTHLFKAGGKRFR
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
PLFTVLSAQIGPDPDAAEVTIAGAVIELVHLATLYHDDVMDEAEVRRGTPTANVRWGNNV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEE
AILAGDYLFATASRLVSRLGPEAVRLIAETFAQLVTGQMRETRGRKQGSDPIEHYLKVVY
EEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EKTACLIAAAGRFGAMFSGADADQVERLSRLGGIVGTAFQISDDIIDIDSDSHESGKLPG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEECCCEEECCCCCCCCCCCCC
TDVREGVHTLPMVYALREPGPDAARLRELLVGPIDDDEVVAEALTLLRASPGMAKAKQSL
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
REYAAQAHRELDQLPDVPGRRALQTLVDFTISRHG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]