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The map label for this gene is menC

Identifier: 41410148

GI number: 41410148

Start: 4510537

End: 4511517

Strand: Direct

Name: menC

Synonym: MAP4050

Alternate gene names: 41410148

Gene position: 4510537-4511517 (Clockwise)

Preceding gene: 41410147

Following gene: 41410149

Centisome position: 93.39

GC content: 76.25

Gene sequence:

>981_bases
GTGATTCCGCCGCTGCAGGACCTGCTGGACCGGCTGCACGTGGTCGCGCTGCCGATGCGGGTGCGATTCCGCGGCATCAC
CACCCGCGAGGTCGCGCTGATCGACGGCCCCGCCGGCTGGGGCGAGTTCGGGGCGTTCGTCGAATACGGGCCGCCCGAGG
CCGCGCACTGGCTGGCGTCGGCCGTCGAGTCCGCCTACCGGCCGGCGCCGCCGGTGCGCCGCGACCGGATCCCGATCAAC
GCCACCGTGCCCGCCGTCCCCCCCGCCGCGGTGCCCGACGTGCTCGCCCGTTTTCCCGGCGCCCGCACCGCCAAGGTCAA
GGTCGCGGAGCCCGGCCAAACCCTGGCCGACGACGTCGCCCGGGTGAATGCGGTGCGCGATTTGGTGCCCACCGTGCGGG
TGGACGCCAACGGCGGCTGGAGCGTGGACGAGGCCGCCCGCGCCGCTCGAGCGCTGAGCGCCGACGGCCCGCTGGAGTAC
CTGGAGCAGCCGTGCGCGACGGTCGGCGAACTCGCCGAGCTGCGCCGCCGGCCGGACATGCCCGACGTGCCGATCGCCGC
CGACGAGAGCATCCGCAAGGCCGACGACCCGCTGGCCGTGGTCCACGCCCGGGCCGCCGACATCGCGGTGCTCAAAGTCG
CTCCGCTGGGCGGGATTTCGGCCCTGCTGGACATCGCCGCCCGCATCGACATCCCGGTCGTGATCTCCAGCGCGCTGGAT
TCGGCCGTCGGCATCGCGGCCGGGCTGACCGCCGCGGCGGCGCTGCCGGTGCTGGGCCACGCGTGCGGGCTGGGCACCGG
CGGGCTGTTCGTGGAGGACGTGGCCGACGTCGCCGCGCCCGTCGACGGCGCCCTGCCGGTCGGGCCGGTGACCCCCGACC
CGGCCCGGTTGCGGGCCCTGGCCGCGCCCCCGCAGCGGCGGCAGTGGTGGATCGACCGGGTCACGGCCTGCCACGGGCTG
CTTGTACCGTCGTCCGGGTGA

Upstream 100 bases:

>100_bases
TGGTGGTGCTGTCCGCCGACCCGCGCGCGGTGCCGCCCGAGCGGATCGCCGACCTGCAGGTGCGGGCGACGTATCTGGCC
GGCCGCCGGGTGTACCCACA

Downstream 100 bases:

>100_bases
TCAACCTGGCTTACGACGACCGCGGCTCCGGCGAGCCCGTGGTCTTTATCGCCGGCCACGGCGGCGCCGGACGGACCTGG
CACCCCTATCAGGTCCCGGC

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIPPLQDLLDRLHVVALPMRVRFRGITTREVALIDGPAGWGEFGAFVEYGPPEAAHWLASAVESAYRPAPPVRRDRIPIN
ATVPAVPPAAVPDVLARFPGARTAKVKVAEPGQTLADDVARVNAVRDLVPTVRVDANGGWSVDEAARAARALSADGPLEY
LEQPCATVGELAELRRRPDMPDVPIAADESIRKADDPLAVVHARAADIAVLKVAPLGGISALLDIAARIDIPVVISSALD
SAVGIAAGLTAAAALPVLGHACGLGTGGLFVEDVADVAAPVDGALPVGPVTPDPARLRALAAPPQRRQWWIDRVTACHGL
LVPSSG

Sequences:

>Translated_326_residues
MIPPLQDLLDRLHVVALPMRVRFRGITTREVALIDGPAGWGEFGAFVEYGPPEAAHWLASAVESAYRPAPPVRRDRIPIN
ATVPAVPPAAVPDVLARFPGARTAKVKVAEPGQTLADDVARVNAVRDLVPTVRVDANGGWSVDEAARAARALSADGPLEY
LEQPCATVGELAELRRRPDMPDVPIAADESIRKADDPLAVVHARAADIAVLKVAPLGGISALLDIAARIDIPVVISSALD
SAVGIAAGLTAAAALPVLGHACGLGTGGLFVEDVADVAAPVDGALPVGPVTPDPARLRALAAPPQRRQWWIDRVTACHGL
LVPSSG
>Mature_326_residues
MIPPLQDLLDRLHVVALPMRVRFRGITTREVALIDGPAGWGEFGAFVEYGPPEAAHWLASAVESAYRPAPPVRRDRIPIN
ATVPAVPPAAVPDVLARFPGARTAKVKVAEPGQTLADDVARVNAVRDLVPTVRVDANGGWSVDEAARAARALSADGPLEY
LEQPCATVGELAELRRRPDMPDVPIAADESIRKADDPLAVVHARAADIAVLKVAPLGGISALLDIAARIDIPVVISSALD
SAVGIAAGLTAAAALPVLGHACGLGTGGLFVEDVADVAAPVDGALPVGPVTPDPARLRALAAPPQRRQWWIDRVTACHGL
LVPSSG

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 33867; Mature: 33867

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPPLQDLLDRLHVVALPMRVRFRGITTREVALIDGPAGWGEFGAFVEYGPPEAAHWLAS
CCCCHHHHHHHHHHHHHHHHHEEECCCEEEEEEEECCCCCHHHCCCEECCCCHHHHHHHH
AVESAYRPAPPVRRDRIPINATVPAVPPAAVPDVLARFPGARTAKVKVAEPGQTLADDVA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHH
RVNAVRDLVPTVRVDANGGWSVDEAARAARALSADGPLEYLEQPCATVGELAELRRRPDM
HHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
PDVPIAADESIRKADDPLAVVHARAADIAVLKVAPLGGISALLDIAARIDIPVVISSALD
CCCCCCCCCHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHH
SAVGIAAGLTAAAALPVLGHACGLGTGGLFVEDVADVAAPVDGALPVGPVTPDPARLRAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
AAPPQRRQWWIDRVTACHGLLVPSSG
CCCCHHHHHHHHHHHHHHCEEECCCC
>Mature Secondary Structure
MIPPLQDLLDRLHVVALPMRVRFRGITTREVALIDGPAGWGEFGAFVEYGPPEAAHWLAS
CCCCHHHHHHHHHHHHHHHHHEEECCCEEEEEEEECCCCCHHHCCCEECCCCHHHHHHHH
AVESAYRPAPPVRRDRIPINATVPAVPPAAVPDVLARFPGARTAKVKVAEPGQTLADDVA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHH
RVNAVRDLVPTVRVDANGGWSVDEAARAARALSADGPLEYLEQPCATVGELAELRRRPDM
HHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
PDVPIAADESIRKADDPLAVVHARAADIAVLKVAPLGGISALLDIAARIDIPVVISSALD
CCCCCCCCCHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHH
SAVGIAAGLTAAAALPVLGHACGLGTGGLFVEDVADVAAPVDGALPVGPVTPDPARLRAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
AAPPQRRQWWIDRVTACHGLLVPSSG
CCCCHHHHHHHHHHHHHHCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]