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The map label for this gene is php [C]

Identifier: 41409766

GI number: 41409766

Start: 4075263

End: 4076243

Strand: Reverse

Name: php [C]

Synonym: MAP3668c

Alternate gene names: 41409766

Gene position: 4076243-4075263 (Counterclockwise)

Preceding gene: 41409771

Following gene: 41409764

Centisome position: 84.4

GC content: 66.67

Gene sequence:

>981_bases
GTGTCAGAACTCAATACCGCTCGCGGGCCCATCGACACCGCTGCGCTGGGTGTCACCCTGATGCACGAACACGTGTTCAT
CATGACCACCGAGATCGCGCAGAACTACCCCGAAGCGTGGGGCGACGAAGAGCAGCGGGTGGCCGACGCCATCGACCGGC
TCAACGAGCTCAAGGCGCGCGGCGTGGACACCATCGTCGACCTCACCGTCATCGGCCTGGGCCGCTACATTCCGCGCATC
GCCCGGGTCGCGGCGGCGACCGAGCTGAATATCGTTGTGGCAACTGGGCTTTACACCTACAATGATGTGCCCTTCTGTTT
CCACTACCTGGGCCCCGGCGCGGAGCTGGGCGGCCCGGAGATCATGACCGACATGTTCGTCCGCGACATCGAGCAGGGCA
TCGCCGACACCGGCATCAAGGCCGGCATCCTCAAGTGCGCCACCGACGCACCCGGCGTCACCCCGGGCGTCGAGCGGGTG
CTGCGGGCGGTGGCGCAGGCGCACAAGCGCACCGGGGTGCCGATCTCCACGCACACCCACGCCGGGCTGCGCCGCGGCCT
CGACCAGCAGCGGATCTTCGAGGAGGAGGGCGTCGACCTGAGCCGGGTGGTGATCGGGCATTCCGGCGACAGCACCGACG
TCGGCTACCTCGAAGAGCTCATCGCCGCCGGCTCGTATCTGGGCATGGACCGGTTCGGCATCGACGCGATCTCGCCGTTC
GAGGACCGGGTGAACATCGTCGCGCAGATGTGCGAGCGCGGCCACGCCGACAAGATGGTGCTCTCGCACGACGCCAACTG
TTATTTCGACGCACTTCCCGAGGAGTTGGTGCCCCAGGTCATGCCGAACTGGCATTACCTGCACATCCACAACGACGTGA
TCCCCGCCCTCAAGCAGCGCGGCGTCACCGACGAGCAGCTGCACACCATGCTCGTCGACAACCCGCGGCGCATCTTCGAG
CGCCAGGGCCCCTATGGGTGA

Upstream 100 bases:

>100_bases
CGCAGACGAGGGTGACGGTAGCGCACCGACGCCCCTGCCGGGGAGGGCAAAACAAAACGACCTCTGTTGGTCAGATGCCG
GTCGACCTAGCATCAGGGGC

Downstream 100 bases:

>100_bases
GCCGGTCCCGCCGATCGGTCCGCGACGAGATCACGGCGCGATTGCGTCGGCCTCAGCGTCGATGAGCTGGCGCGGCGCGG
CGGGCTGGTGGCGTTTCTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSELNTARGPIDTAALGVTLMHEHVFIMTTEIAQNYPEAWGDEEQRVADAIDRLNELKARGVDTIVDLTVIGLGRYIPRI
ARVAAATELNIVVATGLYTYNDVPFCFHYLGPGAELGGPEIMTDMFVRDIEQGIADTGIKAGILKCATDAPGVTPGVERV
LRAVAQAHKRTGVPISTHTHAGLRRGLDQQRIFEEEGVDLSRVVIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDAISPF
EDRVNIVAQMCERGHADKMVLSHDANCYFDALPEELVPQVMPNWHYLHIHNDVIPALKQRGVTDEQLHTMLVDNPRRIFE
RQGPYG

Sequences:

>Translated_326_residues
MSELNTARGPIDTAALGVTLMHEHVFIMTTEIAQNYPEAWGDEEQRVADAIDRLNELKARGVDTIVDLTVIGLGRYIPRI
ARVAAATELNIVVATGLYTYNDVPFCFHYLGPGAELGGPEIMTDMFVRDIEQGIADTGIKAGILKCATDAPGVTPGVERV
LRAVAQAHKRTGVPISTHTHAGLRRGLDQQRIFEEEGVDLSRVVIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDAISPF
EDRVNIVAQMCERGHADKMVLSHDANCYFDALPEELVPQVMPNWHYLHIHNDVIPALKQRGVTDEQLHTMLVDNPRRIFE
RQGPYG
>Mature_325_residues
SELNTARGPIDTAALGVTLMHEHVFIMTTEIAQNYPEAWGDEEQRVADAIDRLNELKARGVDTIVDLTVIGLGRYIPRIA
RVAAATELNIVVATGLYTYNDVPFCFHYLGPGAELGGPEIMTDMFVRDIEQGIADTGIKAGILKCATDAPGVTPGVERVL
RAVAQAHKRTGVPISTHTHAGLRRGLDQQRIFEEEGVDLSRVVIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDAISPFE
DRVNIVAQMCERGHADKMVLSHDANCYFDALPEELVPQVMPNWHYLHIHNDVIPALKQRGVTDEQLHTMLVDNPRRIFER
QGPYG

Specific function: Its Real Enzymatic Activity Is Not Yet Known. It Was Tested For General Esterase, Aminopeptidase, Sulfatase, Phosphatase, Carbonic Anhydrase, Phosphodiesterase, And Phosphotriesterase Activities With The Following Substrates: P- Nitrophenyl Acetate, L-Ala

COG id: COG1735

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphotriesterase family [H]

Homologues:

Organism=Homo sapiens, GI20070186, Length=352, Percent_Identity=24.4318181818182, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI47933341, Length=352, Percent_Identity=24.4318181818182, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1789780, Length=305, Percent_Identity=30.4918032786885, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24645325, Length=361, Percent_Identity=24.0997229916898, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017947
- InterPro:   IPR001559 [H]

Pfam domain/function: PF02126 PTE [H]

EC number: NA

Molecular weight: Translated: 35892; Mature: 35761

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS01322 PHOSPHOTRIESTERASE_1 ; PS01323 PHOSPHOTRIESTERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELNTARGPIDTAALGVTLMHEHVFIMTTEIAQNYPEAWGDEEQRVADAIDRLNELKAR
CCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHC
GVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLYTYNDVPFCFHYLGPGAELGGPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECEEECCCCHHHHHHCCCCCCCCCHH
IMTDMFVRDIEQGIADTGIKAGILKCATDAPGVTPGVERVLRAVAQAHKRTGVPISTHTH
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCH
AGLRRGLDQQRIFEEEGVDLSRVVIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDAISPF
HHHHHCCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCH
EDRVNIVAQMCERGHADKMVLSHDANCYFDALPEELVPQVMPNWHYLHIHNDVIPALKQR
HHHHHHHHHHHHCCCCCCEEEECCCCCHHHCCCHHHHHHHCCCCEEEEECCHHHHHHHHC
GVTDEQLHTMLVDNPRRIFERQGPYG
CCCHHHHHHHHHCCHHHHHHCCCCCC
>Mature Secondary Structure 
SELNTARGPIDTAALGVTLMHEHVFIMTTEIAQNYPEAWGDEEQRVADAIDRLNELKAR
CCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHC
GVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLYTYNDVPFCFHYLGPGAELGGPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECEEECCCCHHHHHHCCCCCCCCCHH
IMTDMFVRDIEQGIADTGIKAGILKCATDAPGVTPGVERVLRAVAQAHKRTGVPISTHTH
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCH
AGLRRGLDQQRIFEEEGVDLSRVVIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDAISPF
HHHHHCCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCH
EDRVNIVAQMCERGHADKMVLSHDANCYFDALPEELVPQVMPNWHYLHIHNDVIPALKQR
HHHHHHHHHHHHCCCCCCEEEECCCCCHHHCCCHHHHHHHCCCCEEEEECCHHHHHHHHC
GVTDEQLHTMLVDNPRRIFERQGPYG
CCCHHHHHHHHHCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]