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The map label for this gene is sigG

Identifier: 41409719

GI number: 41409719

Start: 4018733

End: 4019833

Strand: Reverse

Name: sigG

Synonym: MAP3621c

Alternate gene names: 41409719

Gene position: 4019833-4018733 (Counterclockwise)

Preceding gene: 41409724

Following gene: 41409718

Centisome position: 83.23

GC content: 70.03

Gene sequence:

>1101_bases
CTGCGGGTCCCTCATCATTACCGGCAGCGTAATGGCTGCGGGTCCGCGCCGCGCTTGCAGACACTGCGTACGCTCATGCG
GGTGAGCCTGCTCGCGCAAACCCCTGAAGGTGACTCGGTGGTGGGCGCCGATTTCACCGCGCACGCCGAACCGTACCGGC
GTGAACTGCTGGCCCACTGCTATCGGATGACGGGATCCCTGCACGATGCCGAGGATCTGGTGCAGGAGACGCTGCTGCGG
GCCTGGAAGGCCTACGACCGCTTCGAGGGCAAGTCCTCGGTGCGGACCTGGCTGCATCGCATCGCCACCAACACCTGCCT
GAGCGCGTTGGAAGGCCGGCAGCGCCGGCCGCTCCCGGTGGGACTGGGCGCCCCCAGCGCGGACCCCACCGCCGAGCTGG
TCGAGCGTCGCGAGGTGCCCTGGCTGGAACCGCTGCCGGCGCTGACCGACGACCCGGCCGACCCGTCGGTGATCGTCGGC
TCGCGCGAATCGGTGCGGTTGGCGTTCGTGGCCGCGCTGCAATACCTTTCGCCGCGGCAACGGGCGGTGTTGCTGCTGCG
CGACGTGCTGGGCTGGCGCGCCGCCGAGGTCGCCGAGGCGATCGGCACCACCACGGCCGCCGTCAACAGCCTGCTGCAAC
GCGCCCGCGCCCAGCTGGACGCCGTCGGGCCCAGCGCCGATGACCAACTGGCGCAGCCCGATTCGGCCGAGACCCAAGAC
CTGTTGGCGCGCTACATCGCCGCGTTCGAAAGCTACGACATCGACCGCCTGGTCGAGTTGTTCACCGCGGAGGCGATCTG
GGAAATGCCGCCGTACACCGGGTGGTATCAGGGCGCGCGGACCATCGTCACCCTGATCCATCAGCAATGCCCGGCCGAGG
GCGCCGGCGACATGCGCCTGCTGCCGCTGATCGCCAACGGCCAACCGGCGGCGGCCATGTACATGCGGGCCGGCGACGTC
CATCTGCCCTTCCAGCTGCACGTGCTGGATGTGCGCGGGGACCGGGTTTCGCATGTGGTGGCCTTCCTCGACGACAGCCT
GTTCGCCAAGTTCGGGCTGCCCGCCGCGCTGGGTCCCCGGCAGGAAGGTGTGCGCGCATGA

Upstream 100 bases:

>100_bases
GACAGCACCAGCACCGCGCGCGGCGCGACCTCCGGCGTCCAGACGTCATAGACGATGCGCACACCGCCGACGCCGTCGAA
ACTACGTTCGGTCCGGTTCA

Downstream 100 bases:

>100_bases
CGAGTTCCACCGTCGGGGTCACGCCGGTACCCGGCAACCCGCGGCTGTTGCTGAGCGCCTATGACCTTGCGACGGTCGGA
TACGTCGCCGAGGAGTTCTT

Product: RNA polymerase factor sigma-70

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRVPHHYRQRNGCGSAPRLQTLRTLMRVSLLAQTPEGDSVVGADFTAHAEPYRRELLAHCYRMTGSLHDAEDLVQETLLR
AWKAYDRFEGKSSVRTWLHRIATNTCLSALEGRQRRPLPVGLGAPSADPTAELVERREVPWLEPLPALTDDPADPSVIVG
SRESVRLAFVAALQYLSPRQRAVLLLRDVLGWRAAEVAEAIGTTTAAVNSLLQRARAQLDAVGPSADDQLAQPDSAETQD
LLARYIAAFESYDIDRLVELFTAEAIWEMPPYTGWYQGARTIVTLIHQQCPAEGAGDMRLLPLIANGQPAAAMYMRAGDV
HLPFQLHVLDVRGDRVSHVVAFLDDSLFAKFGLPAALGPRQEGVRA

Sequences:

>Translated_366_residues
MRVPHHYRQRNGCGSAPRLQTLRTLMRVSLLAQTPEGDSVVGADFTAHAEPYRRELLAHCYRMTGSLHDAEDLVQETLLR
AWKAYDRFEGKSSVRTWLHRIATNTCLSALEGRQRRPLPVGLGAPSADPTAELVERREVPWLEPLPALTDDPADPSVIVG
SRESVRLAFVAALQYLSPRQRAVLLLRDVLGWRAAEVAEAIGTTTAAVNSLLQRARAQLDAVGPSADDQLAQPDSAETQD
LLARYIAAFESYDIDRLVELFTAEAIWEMPPYTGWYQGARTIVTLIHQQCPAEGAGDMRLLPLIANGQPAAAMYMRAGDV
HLPFQLHVLDVRGDRVSHVVAFLDDSLFAKFGLPAALGPRQEGVRA
>Mature_366_residues
MRVPHHYRQRNGCGSAPRLQTLRTLMRVSLLAQTPEGDSVVGADFTAHAEPYRRELLAHCYRMTGSLHDAEDLVQETLLR
AWKAYDRFEGKSSVRTWLHRIATNTCLSALEGRQRRPLPVGLGAPSADPTAELVERREVPWLEPLPALTDDPADPSVIVG
SRESVRLAFVAALQYLSPRQRAVLLLRDVLGWRAAEVAEAIGTTTAAVNSLLQRARAQLDAVGPSADDQLAQPDSAETQD
LLARYIAAFESYDIDRLVELFTAEAIWEMPPYTGWYQGARTIVTLIHQQCPAEGAGDMRLLPLIANGQPAAAMYMRAGDV
HLPFQLHVLDVRGDRVSHVVAFLDDSLFAKFGLPAALGPRQEGVRA

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=152, Percent_Identity=31.5789473684211, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014293
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 40352; Mature: 40352

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVPHHYRQRNGCGSAPRLQTLRTLMRVSLLAQTPEGDSVVGADFTAHAEPYRRELLAHC
CCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHH
YRMTGSLHDAEDLVQETLLRAWKAYDRFEGKSSVRTWLHRIATNTCLSALEGRQRRPLPV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
GLGAPSADPTAELVERREVPWLEPLPALTDDPADPSVIVGSRESVRLAFVAALQYLSPRQ
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCHHH
RAVLLLRDVLGWRAAEVAEAIGTTTAAVNSLLQRARAQLDAVGPSADDQLAQPDSAETQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
LLARYIAAFESYDIDRLVELFTAEAIWEMPPYTGWYQGARTIVTLIHQQCPAEGAGDMRL
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
LPLIANGQPAAAMYMRAGDVHLPFQLHVLDVRGDRVSHVVAFLDDSLFAKFGLPAALGPR
EEEEECCCCHHHHHEECCCEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCC
QEGVRA
CCCCCC
>Mature Secondary Structure
MRVPHHYRQRNGCGSAPRLQTLRTLMRVSLLAQTPEGDSVVGADFTAHAEPYRRELLAHC
CCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHH
YRMTGSLHDAEDLVQETLLRAWKAYDRFEGKSSVRTWLHRIATNTCLSALEGRQRRPLPV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
GLGAPSADPTAELVERREVPWLEPLPALTDDPADPSVIVGSRESVRLAFVAALQYLSPRQ
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCHHH
RAVLLLRDVLGWRAAEVAEAIGTTTAAVNSLLQRARAQLDAVGPSADDQLAQPDSAETQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
LLARYIAAFESYDIDRLVELFTAEAIWEMPPYTGWYQGARTIVTLIHQQCPAEGAGDMRL
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
LPLIANGQPAAAMYMRAGDVHLPFQLHVLDVRGDRVSHVVAFLDDSLFAKFGLPAALGPR
EEEEECCCCHHHHHEECCCEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCC
QEGVRA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]