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The map label for this gene is bphF [H]

Identifier: 41409690

GI number: 41409690

Start: 3989623

End: 3990204

Strand: Direct

Name: bphF [H]

Synonym: MAP3592

Alternate gene names: 41409690

Gene position: 3989623-3990204 (Clockwise)

Preceding gene: 41409689

Following gene: 41409691

Centisome position: 82.6

GC content: 73.2

Gene sequence:

>582_bases
GTGCTGCGCCGCATCGAACACCTGCCGATCGGCACCGTGGTGCGCCTGCCCAACGCCGACGCCGCACCGATCGGGCGGGT
GGCCGACGCCGGGGCCGACGCCGTCATCATCGCGATGATCGAGTCGCCCGACCAGGCCGCGGCCGCGGTGGCCGCCACCC
GCTACCCGCCGGCGGGCGTGCGCAGCTTCGGCCCGCTGCGCGCCAGCCTGGGCCATGATCCGGCGGCCCACGAGTCGCGG
GTGAGCGTGTTCGCGATGATCGAGACCGCGGCGGCGCTGTCCGGCATCACCCAGATCTGCGCCGTCGACGGGCTGACCGG
AATCTACGTCGGCCCCGCCGATCTGGCCATCTCGCTGGGCGCCGGCGTGATCGGCGCGACCCGGCAGCCGGAAGTGCTCG
ACGCGATCGTGCACATCCACAAGGCGGCCACCAAGGCCGGCCTGGTCACCGGCATCCACGCCGGGGACGGCAGCACGGGA
CATGCCATGGCGCAGTTGGGATTCGACATGATCACGCTGGCCGCCGAGGCACAGGCACTGCGCCGCGGCGCCGCCGAACA
CCTGCGTGAGGCGACGCAATGA

Upstream 100 bases:

>100_bases
CCCGACACTGCTGGGGCCGGAGGAATTCGCCCGCGCCGGTTACGATTACGTCGGCTTCGACGCCCAGCACGGCTATCTGG
ACGACGCCGACATCGCCGGC

Downstream 100 bases:

>100_bases
CCGGCGGATCGGCCCAGCCGCCGCGGGTGGCGCTGGTGACCGGCGCGGCCGGCGGTCAGGGCCGGGCCATCGCCGAACGG
CTGCGCGGCAACGGGTATGC

Product: hypothetical protein

Products: NA

Alternate protein names: HOA [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MLRRIEHLPIGTVVRLPNADAAPIGRVADAGADAVIIAMIESPDQAAAAVAATRYPPAGVRSFGPLRASLGHDPAAHESR
VSVFAMIETAAALSGITQICAVDGLTGIYVGPADLAISLGAGVIGATRQPEVLDAIVHIHKAATKAGLVTGIHAGDGSTG
HAMAQLGFDMITLAAEAQALRRGAAEHLREATQ

Sequences:

>Translated_193_residues
MLRRIEHLPIGTVVRLPNADAAPIGRVADAGADAVIIAMIESPDQAAAAVAATRYPPAGVRSFGPLRASLGHDPAAHESR
VSVFAMIETAAALSGITQICAVDGLTGIYVGPADLAISLGAGVIGATRQPEVLDAIVHIHKAATKAGLVTGIHAGDGSTG
HAMAQLGFDMITLAAEAQALRRGAAEHLREATQ
>Mature_193_residues
MLRRIEHLPIGTVVRLPNADAAPIGRVADAGADAVIIAMIESPDQAAAAVAATRYPPAGVRSFGPLRASLGHDPAAHESR
VSVFAMIETAAALSGITQICAVDGLTGIYVGPADLAISLGAGVIGATRQPEVLDAIVHIHKAATKAGLVTGIHAGDGSTG
HAMAQLGFDMITLAAEAQALRRGAAEHLREATQ

Specific function: Catalyzes the reversible retro-aldol cleavage of 4- hydroxy-2-oxovalerate to pyruvate and acetaldehyde [H]

COG id: COG3836

COG function: function code G; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789514, Length=147, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1788578, Length=108, Percent_Identity=36.1111111111111, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.39 [H]

Molecular weight: Translated: 19571; Mature: 19571

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRIEHLPIGTVVRLPNADAAPIGRVADAGADAVIIAMIESPDQAAAAVAATRYPPAGV
CCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCC
RSFGPLRASLGHDPAAHESRVSVFAMIETAAALSGITQICAVDGLTGIYVGPADLAISLG
CCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHEEECC
AGVIGATRQPEVLDAIVHIHKAATKAGLVTGIHAGDGSTGHAMAQLGFDMITLAAEAQAL
CCEECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
RRGAAEHLREATQ
HHHHHHHHHHHCC
>Mature Secondary Structure
MLRRIEHLPIGTVVRLPNADAAPIGRVADAGADAVIIAMIESPDQAAAAVAATRYPPAGV
CCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCC
RSFGPLRASLGHDPAAHESRVSVFAMIETAAALSGITQICAVDGLTGIYVGPADLAISLG
CCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHEEECC
AGVIGATRQPEVLDAIVHIHKAATKAGLVTGIHAGDGSTGHAMAQLGFDMITLAAEAQAL
CCEECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
RRGAAEHLREATQ
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10049392 [H]