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The map label for this gene is neoA [H]

Identifier: 41409689

GI number: 41409689

Start: 3988473

End: 3989441

Strand: Direct

Name: neoA [H]

Synonym: MAP3591

Alternate gene names: 41409689

Gene position: 3988473-3989441 (Clockwise)

Preceding gene: 41409688

Following gene: 41409690

Centisome position: 82.58

GC content: 71.83

Gene sequence:

>969_bases
GTGTGGTGCTACCGGATCGTCGCGCCGTATCGGTTCGAACCGACCACGATCGACGACAAGACCCCCGAGTGCCTCGCCGA
CGGGCAAGTGCTGCTGCGGTTTTCGGCCGCCGGCGTGTGCGGCAGCGACCTGCCCGCCTTCCGCGGCGCCCGGGGCCGGC
TGCCCGGTGACGACGGCCGCAGCGGCCCCGAGAAGGACGGCTTTCCCATCCACGAGATCGCCGGCGAGGTGATCGCCAGC
CGGCATCCGGCGCACCGTCCCGGAGACCGCGTCGTCGGCTGGGCATCCGGATTCGACGGCCTGATGGAACGCGTCGTCAG
CGACGGCGACGGGCTGGCGCCCTATGACCCGGCGCTGAGCCCGGCGCAGGCGGTCGAGCTGCAGCCGCTGGCCTGCGTGC
TCTACGCCTGCGAGCAGCTCGGCGAGCTGGCCGGCAAGCACGTCGCGATCATCGGCCAGGGATCGATCGGCCTGCTGTTC
TCCTACGTCGCCAAGGCGGCCGGCGCGCGGCGGGTCACCGGAGTGGACCCGATCGACCGCCGCGACGTGGCAAGGGCGTT
CGGCGTCGACGACCCGGTGCGCGCCACCAGCGACCGCTGGGTCAGCCAGCTCGACCCCGCCGACCGCGCCGACGTCGTCA
TCGAGACCGTCGGCCACCAGGTCGCCACCCTGGCGCACGCCATCGACGCCGCCGCCCCCGGCGGCACCGTGTTCTACTTC
GGTGTGGCCGACGACGACACCTACCCGATCAGCATGCGGACCATGCTGCGCAACAACCTCACCCTGAAATCCGGTGTGAC
ACTGGACCGGCGGCGAATGCTGGAGCTGGCCGGCAAGTTCGCCGCCGAGCATCCCTGGCTGCTGGGCGCCTACCTGACCC
ACACGTTCGGCGTCGACGAGGTGCAGGACGCCTTCGAGCTGGCCTGCCGGCCGGTCGCCGACCGGATCAAGATCGCGATC
GCCGGGTGA

Upstream 100 bases:

>100_bases
CTGCGCCGGGTGCCCGACTACGCGATCCGGGCCGACGCCGCCACCCGGTTGCCGTCCAGCTTCCAATGGGGCTGGAACAA
GATCCCGGTGGAGGTCTGAG

Downstream 100 bases:

>100_bases
GTGGCCGACCGTGACCGCGCCGAGCAACCTGCGGCTGGCCCTGAACCGGCGGTCCCCGATATTCGGCGGCTGGGTCACCG
GCCCGACACTGCTGGGGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: DOIA dehydrogenase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MWCYRIVAPYRFEPTTIDDKTPECLADGQVLLRFSAAGVCGSDLPAFRGARGRLPGDDGRSGPEKDGFPIHEIAGEVIAS
RHPAHRPGDRVVGWASGFDGLMERVVSDGDGLAPYDPALSPAQAVELQPLACVLYACEQLGELAGKHVAIIGQGSIGLLF
SYVAKAAGARRVTGVDPIDRRDVARAFGVDDPVRATSDRWVSQLDPADRADVVIETVGHQVATLAHAIDAAAPGGTVFYF
GVADDDTYPISMRTMLRNNLTLKSGVTLDRRRMLELAGKFAAEHPWLLGAYLTHTFGVDEVQDAFELACRPVADRIKIAI
AG

Sequences:

>Translated_322_residues
MWCYRIVAPYRFEPTTIDDKTPECLADGQVLLRFSAAGVCGSDLPAFRGARGRLPGDDGRSGPEKDGFPIHEIAGEVIAS
RHPAHRPGDRVVGWASGFDGLMERVVSDGDGLAPYDPALSPAQAVELQPLACVLYACEQLGELAGKHVAIIGQGSIGLLF
SYVAKAAGARRVTGVDPIDRRDVARAFGVDDPVRATSDRWVSQLDPADRADVVIETVGHQVATLAHAIDAAAPGGTVFYF
GVADDDTYPISMRTMLRNNLTLKSGVTLDRRRMLELAGKFAAEHPWLLGAYLTHTFGVDEVQDAFELACRPVADRIKIAI
AG
>Mature_322_residues
MWCYRIVAPYRFEPTTIDDKTPECLADGQVLLRFSAAGVCGSDLPAFRGARGRLPGDDGRSGPEKDGFPIHEIAGEVIAS
RHPAHRPGDRVVGWASGFDGLMERVVSDGDGLAPYDPALSPAQAVELQPLACVLYACEQLGELAGKHVAIIGQGSIGLLF
SYVAKAAGARRVTGVDPIDRRDVARAFGVDDPVRATSDRWVSQLDPADRADVVIETVGHQVATLAHAIDAAAPGGTVFYF
GVADDDTYPISMRTMLRNNLTLKSGVTLDRRRMLELAGKFAAEHPWLLGAYLTHTFGVDEVQDAFELACRPVADRIKIAI
AG

Specific function: Catalyzes the oxidation of 2-deoxy-scyllo-inosamine (DOIA) with NAD(+) or NADP(+), forming 3-amino-2,3-dideoxy-scyllo- inosose (amino-DOI) [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. DOIA dehydrogenase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 34520; Mature: 34520

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWCYRIVAPYRFEPTTIDDKTPECLADGQVLLRFSAAGVCGSDLPAFRGARGRLPGDDGR
CCEEEEECCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCCCCCCHHCCCCCCCCCCCCC
SGPEKDGFPIHEIAGEVIASRHPAHRPGDRVVGWASGFDGLMERVVSDGDGLAPYDPALS
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCC
PAQAVELQPLACVLYACEQLGELAGKHVAIIGQGSIGLLFSYVAKAAGARRVTGVDPIDR
CHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCH
RDVARAFGVDDPVRATSDRWVSQLDPADRADVVIETVGHQVATLAHAIDAAAPGGTVFYF
HHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
GVADDDTYPISMRTMLRNNLTLKSGVTLDRRRMLELAGKFAAEHPWLLGAYLTHTFGVDE
EECCCCCCCHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHH
VQDAFELACRPVADRIKIAIAG
HHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MWCYRIVAPYRFEPTTIDDKTPECLADGQVLLRFSAAGVCGSDLPAFRGARGRLPGDDGR
CCEEEEECCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCCCCCCHHCCCCCCCCCCCCC
SGPEKDGFPIHEIAGEVIASRHPAHRPGDRVVGWASGFDGLMERVVSDGDGLAPYDPALS
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCC
PAQAVELQPLACVLYACEQLGELAGKHVAIIGQGSIGLLFSYVAKAAGARRVTGVDPIDR
CHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCH
RDVARAFGVDDPVRATSDRWVSQLDPADRADVVIETVGHQVATLAHAIDAAAPGGTVFYF
HHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
GVADDDTYPISMRTMLRNNLTLKSGVTLDRRRMLELAGKFAAEHPWLLGAYLTHTFGVDE
EECCCCCCCHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHH
VQDAFELACRPVADRIKIAIAG
HHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA