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The map label for this gene is fabR [H]

Identifier: 41409642

GI number: 41409642

Start: 3946007

End: 3946759

Strand: Reverse

Name: fabR [H]

Synonym: MAP3544c

Alternate gene names: 41409642

Gene position: 3946759-3946007 (Counterclockwise)

Preceding gene: 41409645

Following gene: 41409639

Centisome position: 81.72

GC content: 67.6

Gene sequence:

>753_bases
GTGAACATACGTACACCGTTGCTCCGCCCCGGCCGAGCAGTCAAGGGTTTACTGCCCGTATGTGGTAGGGTTCACATAGT
GAACAGCCGTACTCCTAGCTCACGGGTGCGCGGCTCCGGACGCGAGCGCTCCCGCGAAAGCCAGTCACGGGAAGAGCGCA
AGGAGGCGACCCGTCGCGCCATCATCGCCGCCGCCCTCAAGCTGCTGCAGGACCGCAGTTTCTCCAGCCTGAGCCTGCGC
GAGGTGACCCGAGAGGTCGGGATCGTGCCGGCGGCGTTCTACCGGCACTTCGAGTCGATGGAATCCCTGGGTCTGGTGCT
GATCGACGAGTCGTTCCGCAGCCTGCGCGACACCCTGCGCGACGCCCGGGCCGGCAAGCTCGACCCGAACCGGGTGATCG
AGTCATCGGTGGAGATCCTGGTGGCCAGCGTCGCGGACCGGCGCGAGCATTGGCGGCTGATCGCCCGCGAGCGCAACAGC
GGGCTGTCGGTGCTGCGCTACGCCATCCGCACCGAGATCCGGCTGATCACCTCCGAGCTGGCCACCGACCTGGCCCGGTT
TCCCGGCCTGCACGAGTGGACCACCGAGGACCTCAACGTGCTGGCGACCCTGTTCGTCAACGCCATGATCGTCATCGCCG
AGGCCATCGAGGATTCGCAGAGCGCCGAGGCGCGCGAGGACATCCGCCGGCTGGCCGTCAAGCAGTTGCGGATGATCGCC
ACCGGCATCGCCGGCTGGCACAGCACGCCCTAG

Upstream 100 bases:

>100_bases
GACGCCGTGCGGACCGGTCAGCAGGTCGAGCAGCTCCGAACCCAGCACCCGCTGCCGCACGGTCCGCGCGAGGACCCGGC
CGGAAGCCTGAACAGTTTGA

Downstream 100 bases:

>100_bases
ATCACGTCGGCTGCAGTAAACACGCGAGCACTGACTTACTCGTCGACGACGTCGTACAGTGAGTCGCCGTCCTCGGGGGT
GCCGTCAACCTGGCCCCGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNIRTPLLRPGRAVKGLLPVCGRVHIVNSRTPSSRVRGSGRERSRESQSREERKEATRRAIIAAALKLLQDRSFSSLSLR
EVTREVGIVPAAFYRHFESMESLGLVLIDESFRSLRDTLRDARAGKLDPNRVIESSVEILVASVADRREHWRLIARERNS
GLSVLRYAIRTEIRLITSELATDLARFPGLHEWTTEDLNVLATLFVNAMIVIAEAIEDSQSAEAREDIRRLAVKQLRMIA
TGIAGWHSTP

Sequences:

>Translated_250_residues
MNIRTPLLRPGRAVKGLLPVCGRVHIVNSRTPSSRVRGSGRERSRESQSREERKEATRRAIIAAALKLLQDRSFSSLSLR
EVTREVGIVPAAFYRHFESMESLGLVLIDESFRSLRDTLRDARAGKLDPNRVIESSVEILVASVADRREHWRLIARERNS
GLSVLRYAIRTEIRLITSELATDLARFPGLHEWTTEDLNVLATLFVNAMIVIAEAIEDSQSAEAREDIRRLAVKQLRMIA
TGIAGWHSTP
>Mature_250_residues
MNIRTPLLRPGRAVKGLLPVCGRVHIVNSRTPSSRVRGSGRERSRESQSREERKEATRRAIIAAALKLLQDRSFSSLSLR
EVTREVGIVPAAFYRHFESMESLGLVLIDESFRSLRDTLRDARAGKLDPNRVIESSVEILVASVADRREHWRLIARERNS
GLSVLRYAIRTEIRLITSELATDLARFPGLHEWTTEDLNVLATLFVNAMIVIAEAIEDSQSAEAREDIRRLAVKQLRMIA
TGIAGWHSTP

Specific function: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, fabR directly influences the physical properties of the membrane bilayer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693209, Length=202, Percent_Identity=36.6336633663366, Blast_Score=106, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 28185; Mature: 28185

Theoretical pI: Translated: 11.18; Mature: 11.18

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRTPLLRPGRAVKGLLPVCGRVHIVNSRTPSSRVRGSGRERSRESQSREERKEATRRA
CCCCCCCCCCCHHHHHHHHHHCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IIAAALKLLQDRSFSSLSLREVTREVGIVPAAFYRHFESMESLGLVLIDESFRSLRDTLR
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHH
DARAGKLDPNRVIESSVEILVASVADRREHWRLIARERNSGLSVLRYAIRTEIRLITSEL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ATDLARFPGLHEWTTEDLNVLATLFVNAMIVIAEAIEDSQSAEAREDIRRLAVKQLRMIA
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TGIAGWHSTP
HHHCCCCCCC
>Mature Secondary Structure
MNIRTPLLRPGRAVKGLLPVCGRVHIVNSRTPSSRVRGSGRERSRESQSREERKEATRRA
CCCCCCCCCCCHHHHHHHHHHCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IIAAALKLLQDRSFSSLSLREVTREVGIVPAAFYRHFESMESLGLVLIDESFRSLRDTLR
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHH
DARAGKLDPNRVIESSVEILVASVADRREHWRLIARERNSGLSVLRYAIRTEIRLITSEL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ATDLARFPGLHEWTTEDLNVLATLFVNAMIVIAEAIEDSQSAEAREDIRRLAVKQLRMIA
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TGIAGWHSTP
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA