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The map label for this gene is oxyS_1

Identifier: 41409620

GI number: 41409620

Start: 3922455

End: 3923393

Strand: Direct

Name: oxyS_1

Synonym: MAP3522

Alternate gene names: 41409620

Gene position: 3922455-3923393 (Clockwise)

Preceding gene: 41409619

Following gene: 41409622

Centisome position: 81.21

GC content: 70.39

Gene sequence:

>939_bases
GTGCGGGTGCTGTTCCGTCAGCTGGAGTACTTCGTGGCGGTGGCCTCCGAGCGGCACTTCGCCCGGGCCGCCGAGAAGTG
CTTCGTGTCCCAGCCGGCGCTGTCCGCCGCGATCGCCAAGCTGGAAAAGGAGCTGAACGTCACGCTGATCAATCGTGGCC
ACAGTTTCGAGGGCCTCACCCCCGAGGGTGAGCGATTGGTGGTGTGGGCCAGGCGGATTCTCGCCGAGCACGACGCGTTC
AAGGCCGAGGTCGACGCCGTGCGGTCGGGGGTCACCGGGACGCTTCGGCTGGGCACCGTGCCGACCGCGTCCACCACCGC
GTCCCTGCTGCTGTCCGCGTTCTGCTCCGCGCACCCGTTGGTGAAGGTGCAGATCCTATCCCGGCTGTCGGCCGGCGAGC
TGTACCGGCGGTTGCGCGAGTTCGAACTCGACGCCGCCATCGCCCACACCGCGCCCGACGACATCCCCGACGTGAACCTG
GTGCCGCTCTACCGGGAGCGTTATGTGTTGCTGGCACCGGCGGACCTGCTGGCATCCGGCGCCGCCACCATGACCTGGGT
GCAGGCCGCCCAGTTGCCGCTGGCCCTGCTCACCCCGGACATGCGGGACCGCCAGATCATCGACCGGGCGTTCGCCGACC
ACGGCATCACGTTGCACCCGCAGGTCGAAACCGACTCCGTGGCTTCGCTGTTCGCGCAGGCGTCGGCGGGTAGTTGGGCG
TCCATCGTGCCGCACACCTGGCTGTGGGCATCGCCGCTGGGCGCCGGCATCCGGGCGGTGGAGTTGGTCGATCCGGTGCT
CACCGCGGACGTGGTGCTGGCCACCAAGTCGCACGGTCCCGGCTCGCCGATCGCGCGGGCGCTGGCCGCGTCCGCCGGCC
GGCTGCAGCTGAACGACTTCTTCGACGCGCAGCTGCTGGGCGTCACGCGCCGGCGCTGA

Upstream 100 bases:

>100_bases
GGTGGCGGTGCGCGACACCGCGCAGACGCTGGATTGGCTCGGCGGGTAGCCGCGGGTTAGCCTCGGCGAGATCGCAAGGC
CGAGCCCGACCACGACAGGA

Downstream 100 bases:

>100_bases
CCGCGGCCGGCGACGCCGCGCTGGCCGGGTTCCGGTTGGCCAGGTGGCCGCTTTCCACCCCGGCGGTCGGATCGAGCTCG
CAGTCGATCAGCGACGGCCC

Product: OxyS_1

Products: NA

Alternate protein names: Cyn operon transcriptional activator [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRVLFRQLEYFVAVASERHFARAAEKCFVSQPALSAAIAKLEKELNVTLINRGHSFEGLTPEGERLVVWARRILAEHDAF
KAEVDAVRSGVTGTLRLGTVPTASTTASLLLSAFCSAHPLVKVQILSRLSAGELYRRLREFELDAAIAHTAPDDIPDVNL
VPLYRERYVLLAPADLLASGAATMTWVQAAQLPLALLTPDMRDRQIIDRAFADHGITLHPQVETDSVASLFAQASAGSWA
SIVPHTWLWASPLGAGIRAVELVDPVLTADVVLATKSHGPGSPIARALAASAGRLQLNDFFDAQLLGVTRRR

Sequences:

>Translated_312_residues
MRVLFRQLEYFVAVASERHFARAAEKCFVSQPALSAAIAKLEKELNVTLINRGHSFEGLTPEGERLVVWARRILAEHDAF
KAEVDAVRSGVTGTLRLGTVPTASTTASLLLSAFCSAHPLVKVQILSRLSAGELYRRLREFELDAAIAHTAPDDIPDVNL
VPLYRERYVLLAPADLLASGAATMTWVQAAQLPLALLTPDMRDRQIIDRAFADHGITLHPQVETDSVASLFAQASAGSWA
SIVPHTWLWASPLGAGIRAVELVDPVLTADVVLATKSHGPGSPIARALAASAGRLQLNDFFDAQLLGVTRRR
>Mature_312_residues
MRVLFRQLEYFVAVASERHFARAAEKCFVSQPALSAAIAKLEKELNVTLINRGHSFEGLTPEGERLVVWARRILAEHDAF
KAEVDAVRSGVTGTLRLGTVPTASTTASLLLSAFCSAHPLVKVQILSRLSAGELYRRLREFELDAAIAHTAPDDIPDVNL
VPLYRERYVLLAPADLLASGAATMTWVQAAQLPLALLTPDMRDRQIIDRAFADHGITLHPQVETDSVASLFAQASAGSWA
SIVPHTWLWASPLGAGIRAVELVDPVLTADVVLATKSHGPGSPIARALAASAGRLQLNDFFDAQLLGVTRRR

Specific function: Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR- cynTSX intergenic region [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=29.757785467128, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790399, Length=98, Percent_Identity=43.8775510204082, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787879, Length=307, Percent_Identity=28.3387622149837, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787530, Length=272, Percent_Identity=27.5735294117647, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=28.8617886178862, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788296, Length=215, Percent_Identity=27.906976744186, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI2367136, Length=290, Percent_Identity=24.4827586206897, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=291, Percent_Identity=23.7113402061856, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788748, Length=294, Percent_Identity=26.1904761904762, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788887, Length=172, Percent_Identity=30.8139534883721, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33807; Mature: 33807

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLFRQLEYFVAVASERHFARAAEKCFVSQPALSAAIAKLEKELNVTLINRGHSFEGLT
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCCCC
PEGERLVVWARRILAEHDAFKAEVDAVRSGVTGTLRLGTVPTASTTASLLLSAFCSAHPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
VKVQILSRLSAGELYRRLREFELDAAIAHTAPDDIPDVNLVPLYRERYVLLAPADLLASG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHCCCEEEEECHHHHHCC
AATMTWVQAAQLPLALLTPDMRDRQIIDRAFADHGITLHPQVETDSVASLFAQASAGSWA
CHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHCCCCCH
SIVPHTWLWASPLGAGIRAVELVDPVLTADVVLATKSHGPGSPIARALAASAGRLQLNDF
HHCCCCHHHHCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHCCCCEEECHH
FDAQLLGVTRRR
HCHHHHHHCCCC
>Mature Secondary Structure
MRVLFRQLEYFVAVASERHFARAAEKCFVSQPALSAAIAKLEKELNVTLINRGHSFEGLT
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCCCC
PEGERLVVWARRILAEHDAFKAEVDAVRSGVTGTLRLGTVPTASTTASLLLSAFCSAHPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
VKVQILSRLSAGELYRRLREFELDAAIAHTAPDDIPDVNLVPLYRERYVLLAPADLLASG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHCCCEEEEECHHHHHCC
AATMTWVQAAQLPLALLTPDMRDRQIIDRAFADHGITLHPQVETDSVASLFAQASAGSWA
CHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHCCCCCH
SIVPHTWLWASPLGAGIRAVELVDPVLTADVVLATKSHGPGSPIARALAASAGRLQLNDF
HHCCCCHHHHCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHCCCCEEECHH
FDAQLLGVTRRR
HCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]