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The map label for this gene is iunH

Identifier: 41409582

GI number: 41409582

Start: 3872181

End: 3873212

Strand: Direct

Name: iunH

Synonym: MAP3484

Alternate gene names: 41409582

Gene position: 3872181-3873212 (Clockwise)

Preceding gene: 41409581

Following gene: 41409583

Centisome position: 80.17

GC content: 71.12

Gene sequence:

>1032_bases
GTGACTCCAGTTTTCGTCGATGTCGACACCGGCGTGGATGATGCGCTGGCGCTGATGTACCTGTTCGCCAGCCCGGACGC
CGACGTGGTCGGCATCGCATCGACCGGCGGAAACGTTGCGGTGGAGCAGGTTTGCGAAAACAACCTGGGCCTGCTGCAGC
TGTGCGGGCTGACCGGCATCCCGGTGTCCAAGGGTTCCGGGCAGACCCTGACCGGCCCGATGCGGCTGCCATCAAAAGTC
CACGGCCCCAGGGGATTGGGCTATGCCGAGCTGCCGCCCAGCGACCACCGGGTCACCGACCACGACTCGGCAACCGCCTG
GGTGTGCGCCGCGCACGCCCACCCCGGGGAGCTGATCGGGGTGGCGACCGGGCCGCTGACCAACCTGGCGCTGGCGCTGC
GGGCCGAGCCCGCGCTGCCGACCCTGCTGCGCCGGCTGGTGATCATGGGCGGCTCCTACGACCATCGGGGCAACACCACC
GCGGTGGCGGAATGGAACATCAGCGTGGACCCCGAGGCCGCGGCCGAGGTGCTGGCCGGCTGGGGTGGCGCCGACGTCGG
GCGGGAGCGGCTGCCGATCCTGTGCGGGCTGGACCTGACCCGCAAGGTGGCGATGACGCCGGGTCACCTGACGCGGCTGG
CCACCGCCGCGGACTCCAGCACCCGCCCGCTGAGCGCCGACGACGAACCCGGAACCCGGTCGGCGGCCGCCAACCCGCTG
ATCCGGGTGATCGAGGACGCGATGCGGTTCTACCTGGAGGCCTATCACGACCTCGGCCACGGCTATCAGGCGCACATGCA
CGACCCGTTGGCCGCCGCCGTCGCGCTGGACCCCACGCTGGTGGCCACGCGTCCGGCGACGGTGGAGATCGAGCTGACCG
GCACCCTGACCCGCGCCATGACGGTCACCGACTGGTCGGGTCGTCGAGAACCCAACGCGCTCATCGGGATTGATGTGGAC
TCGGCGGCATTCTTCGACCGGTTCATCGAACGGGTGGGGCCGTTCGCCCGCCGGGTGGGCGGCGGCCGGTGA

Upstream 100 bases:

>100_bases
CCGATCCGGCCGCTCGAGGGCGACGGCCCGGCCCGCCGGGACGTCCTGGTGATCACCTTCGCGTCCGGCCGTCCCTGATC
GTCGCGGTATCGTGGCCGCG

Downstream 100 bases:

>100_bases
CGACGGTATCCGCAAAACGAAGGCGGGCCGTCATACGAAAATCGGCGGTTGCCGGTCACCTGCGCCGGTGACGTCGGCGG
ATTGTGTTTTCATGAAGATG

Product: IunH

Products: NA

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTPVFVDVDTGVDDALALMYLFASPDADVVGIASTGGNVAVEQVCENNLGLLQLCGLTGIPVSKGSGQTLTGPMRLPSKV
HGPRGLGYAELPPSDHRVTDHDSATAWVCAAHAHPGELIGVATGPLTNLALALRAEPALPTLLRRLVIMGGSYDHRGNTT
AVAEWNISVDPEAAAEVLAGWGGADVGRERLPILCGLDLTRKVAMTPGHLTRLATAADSSTRPLSADDEPGTRSAAANPL
IRVIEDAMRFYLEAYHDLGHGYQAHMHDPLAAAVALDPTLVATRPATVEIELTGTLTRAMTVTDWSGRREPNALIGIDVD
SAAFFDRFIERVGPFARRVGGGR

Sequences:

>Translated_343_residues
MTPVFVDVDTGVDDALALMYLFASPDADVVGIASTGGNVAVEQVCENNLGLLQLCGLTGIPVSKGSGQTLTGPMRLPSKV
HGPRGLGYAELPPSDHRVTDHDSATAWVCAAHAHPGELIGVATGPLTNLALALRAEPALPTLLRRLVIMGGSYDHRGNTT
AVAEWNISVDPEAAAEVLAGWGGADVGRERLPILCGLDLTRKVAMTPGHLTRLATAADSSTRPLSADDEPGTRSAAANPL
IRVIEDAMRFYLEAYHDLGHGYQAHMHDPLAAAVALDPTLVATRPATVEIELTGTLTRAMTVTDWSGRREPNALIGIDVD
SAAFFDRFIERVGPFARRVGGGR
>Mature_342_residues
TPVFVDVDTGVDDALALMYLFASPDADVVGIASTGGNVAVEQVCENNLGLLQLCGLTGIPVSKGSGQTLTGPMRLPSKVH
GPRGLGYAELPPSDHRVTDHDSATAWVCAAHAHPGELIGVATGPLTNLALALRAEPALPTLLRRLVIMGGSYDHRGNTTA
VAEWNISVDPEAAAEVLAGWGGADVGRERLPILCGLDLTRKVAMTPGHLTRLATAADSSTRPLSADDEPGTRSAAANPLI
RVIEDAMRFYLEAYHDLGHGYQAHMHDPLAAAVALDPTLVATRPATVEIELTGTLTRAMTVTDWSGRREPNALIGIDVDS
AAFFDRFIERVGPFARRVGGGR

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=338, Percent_Identity=32.2485207100592, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786213, Length=324, Percent_Identity=30.5555555555556, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788486, Length=325, Percent_Identity=26.7692307692308, Blast_Score=107, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17565698, Length=324, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32565474, Length=186, Percent_Identity=30.6451612903226, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320608, Length=346, Percent_Identity=26.878612716763, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641837, Length=199, Percent_Identity=33.6683417085427, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: 3.2.2.-

Molecular weight: Translated: 36099; Mature: 35968

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVFVDVDTGVDDALALMYLFASPDADVVGIASTGGNVAVEQVCENNLGLLQLCGLTGI
CCCEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEECCCCCC
PVSKGSGQTLTGPMRLPSKVHGPRGLGYAELPPSDHRVTDHDSATAWVCAAHAHPGELIG
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCCEEE
VATGPLTNLALALRAEPALPTLLRRLVIMGGSYDHRGNTTAVAEWNISVDPEAAAEVLAG
EECCCHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHC
WGGADVGRERLPILCGLDLTRKVAMTPGHLTRLATAADSSTRPLSADDEPGTRSAAANPL
CCCCCCCCCCCCEEECCCCHHHEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
IRVIEDAMRFYLEAYHDLGHGYQAHMHDPLAAAVALDPTLVATRPATVEIELTGTLTRAM
HHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHEECCCEEEECCCCEEEEEEEEEEEEEE
TVTDWSGRREPNALIGIDVDSAAFFDRFIERVGPFARRVGGGR
EEECCCCCCCCCEEEEEECCHHHHHHHHHHHHCHHHHHHCCCC
>Mature Secondary Structure 
TPVFVDVDTGVDDALALMYLFASPDADVVGIASTGGNVAVEQVCENNLGLLQLCGLTGI
CCEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEECCCCCC
PVSKGSGQTLTGPMRLPSKVHGPRGLGYAELPPSDHRVTDHDSATAWVCAAHAHPGELIG
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCCEEE
VATGPLTNLALALRAEPALPTLLRRLVIMGGSYDHRGNTTAVAEWNISVDPEAAAEVLAG
EECCCHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHC
WGGADVGRERLPILCGLDLTRKVAMTPGHLTRLATAADSSTRPLSADDEPGTRSAAANPL
CCCCCCCCCCCCEEECCCCHHHEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
IRVIEDAMRFYLEAYHDLGHGYQAHMHDPLAAAVALDPTLVATRPATVEIELTGTLTRAM
HHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHEECCCEEEECCCCEEEEEEEEEEEEEE
TVTDWSGRREPNALIGIDVDSAAFFDRFIERVGPFARRVGGGR
EEECCCCCCCCCEEEEEECCHHHHHHHHHHHHCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA