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The map label for this gene is manB

Identifier: 41409467

GI number: 41409467

Start: 3743717

End: 3745132

Strand: Reverse

Name: manB

Synonym: MAP3369c

Alternate gene names: 41409467

Gene position: 3745132-3743717 (Counterclockwise)

Preceding gene: 41409468

Following gene: 41409466

Centisome position: 77.54

GC content: 72.03

Gene sequence:

>1416_bases
ATGTCCCGGCCCGCCGCGACTGTCCACCGTGTCGTCAAGGCGTACGACGTGCGTGGGCTGGTCGGCGAAGAGCTCGACCA
GCCGCTGGTCGCCGACCTCGGCGCGGCCTTCGCCAAAGTGATGCGCGCCGAGGGCGCCGGCCAGGTCGTCATCGGCCACG
ACATGCGCGACAGCTCACCCACCCTGGCCGCCGCGTTCGCCGCCGGGGTGACCGGGCAGGGTCTGGACGTGGTGCGCATC
GGGCTGGCGTCCACCGATCAGCTCTACTTCGCCTCCGGCCTGCTGGACTGCCCCGGCGCGATGTTCACCGCGAGCCACAA
CCCGGCGGCCTACAACGGGATCAAGCTGTGCCGCGCCGGCGCCCGGCCGGTCGGCGCCGACAGCGGGTTGCGCACCATCG
CCGACGACGTGATCGCCGGCGTCGAGGACTACGACGGGCCACCGGGATCGGTCGGCGACCGCGACGTGCTGGCCGACTAC
GGGCGGTTCCTGCGCTCGCTGGTAGACACCTCCGGGCTGCGCCCGCTGCGGGTCGCCGTCGACGCCGGCAACGGCATGGC
CGGCCTCACCACACCCGCGGTGCTCGGCCCGATCGAGTCGATCACGTTGGCGCCCTTGTACTTCGAGCTCGACGGCTCCT
TCCCGCACCACGAGGCCAACCCGCTGGACCCGGCCAACCTGGTCGACCTGCAGGCCTACGTGCGCGAGACCGGCGCCGAC
ATCGGCCTGGCCTTCGACGGCGACGCCGATCGCTGCTTCGTGGTCGACGAGCGCGGCAACCCGGTGTCGCCGTCGACCGT
GACCAGCCTGGTGGCCGCCCGCGAACTCGGCCGCGAGATCGGCGCGACGATCATCCACAACGTGATCACCTCGCGCGCGG
TGCCCGAGCTGGTCAGCGAGCGCGGCGGCACACCGCTGCGCTCGCGGGTGGGGCACTCCTACATCAAGGCGCTGATGGCC
GACACCGGCGCGATCTTCGGCGGCGAGCACTCGGCGCACTACTACTTCCGCGACTTCTGGGGCGCCGACTCGGGGATGCT
GGCCGCGCTGTACGTGCTGGCCGCCCTCGGCGAACAGGACCGCCCGCTGTCCGAGCTGACCGCGGACTACCAGCGCTACG
AGTCGTCCGGCGAGATCAACTTCACCGTCGCCGACGCCGGGCAGTGCACCGAAGCGGTGCTGAGGTCGTTCGGCACCCGG
ATCCACTCCCTGGACCACGTGGACGGGGTGACCGTGGACCTGGGCGACGGCAGCTGGTTCAACCTGCGCAGCTCCAACAC
CGAACCGCTGCTGCGGCTCAACGTGGAGGGCCGCACGGCAGAGGACGTCGCCGCGGTGGTCGCCCAGATCAGCGCCGAGA
TCGCCGCGATCACCGCGGGAACGACGACCGAGGCGGACGCGGGGGCGGCGCCGTGA

Upstream 100 bases:

>100_bases
CCGATGGGGGCGCACCCGAATCCGCGCGCACCGCGGCGGCCGGTGTTCTCCCCGGCCCGATAGGCTGGCGGCCAAGAGTT
CACGTCGTCAGGAGTCCCGC

Downstream 100 bases:

>100_bases
ACGCCACCCGCGCAATCGATCTGGAGGACACCGAGGGCCTGCTGAGCGCCGACCGCGACGGCCTGCTGCGGGCCGCGTCG
TCGGCCGGCGCGCAGGTGCG

Product: phosphomannomutase/phosphoglucomutase

Products: NA

Alternate protein names: Phosphoglucomutase; PGM; Glucose phosphomutase; Phosphomannomutase; PMM [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSRPAATVHRVVKAYDVRGLVGEELDQPLVADLGAAFAKVMRAEGAGQVVIGHDMRDSSPTLAAAFAAGVTGQGLDVVRI
GLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGARPVGADSGLRTIADDVIAGVEDYDGPPGSVGDRDVLADY
GRFLRSLVDTSGLRPLRVAVDAGNGMAGLTTPAVLGPIESITLAPLYFELDGSFPHHEANPLDPANLVDLQAYVRETGAD
IGLAFDGDADRCFVVDERGNPVSPSTVTSLVAARELGREIGATIIHNVITSRAVPELVSERGGTPLRSRVGHSYIKALMA
DTGAIFGGEHSAHYYFRDFWGADSGMLAALYVLAALGEQDRPLSELTADYQRYESSGEINFTVADAGQCTEAVLRSFGTR
IHSLDHVDGVTVDLGDGSWFNLRSSNTEPLLRLNVEGRTAEDVAAVVAQISAEIAAITAGTTTEADAGAAP

Sequences:

>Translated_471_residues
MSRPAATVHRVVKAYDVRGLVGEELDQPLVADLGAAFAKVMRAEGAGQVVIGHDMRDSSPTLAAAFAAGVTGQGLDVVRI
GLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGARPVGADSGLRTIADDVIAGVEDYDGPPGSVGDRDVLADY
GRFLRSLVDTSGLRPLRVAVDAGNGMAGLTTPAVLGPIESITLAPLYFELDGSFPHHEANPLDPANLVDLQAYVRETGAD
IGLAFDGDADRCFVVDERGNPVSPSTVTSLVAARELGREIGATIIHNVITSRAVPELVSERGGTPLRSRVGHSYIKALMA
DTGAIFGGEHSAHYYFRDFWGADSGMLAALYVLAALGEQDRPLSELTADYQRYESSGEINFTVADAGQCTEAVLRSFGTR
IHSLDHVDGVTVDLGDGSWFNLRSSNTEPLLRLNVEGRTAEDVAAVVAQISAEIAAITAGTTTEADAGAAP
>Mature_470_residues
SRPAATVHRVVKAYDVRGLVGEELDQPLVADLGAAFAKVMRAEGAGQVVIGHDMRDSSPTLAAAFAAGVTGQGLDVVRIG
LASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGARPVGADSGLRTIADDVIAGVEDYDGPPGSVGDRDVLADYG
RFLRSLVDTSGLRPLRVAVDAGNGMAGLTTPAVLGPIESITLAPLYFELDGSFPHHEANPLDPANLVDLQAYVRETGADI
GLAFDGDADRCFVVDERGNPVSPSTVTSLVAARELGREIGATIIHNVITSRAVPELVSERGGTPLRSRVGHSYIKALMAD
TGAIFGGEHSAHYYFRDFWGADSGMLAALYVLAALGEQDRPLSELTADYQRYESSGEINFTVADAGQCTEAVLRSFGTRI
HSLDHVDGVTVDLGDGSWFNLRSSNTEPLLRLNVEGRTAEDVAAVVAQISAEIAAITAGTTTEADAGAAP

Specific function: Involved in xanthan production [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=438, Percent_Identity=38.5844748858447, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1789566, Length=451, Percent_Identity=27.2727272727273, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2; =5.4.2.8 [H]

Molecular weight: Translated: 49268; Mature: 49136

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPAATVHRVVKAYDVRGLVGEELDQPLVADLGAAFAKVMRAEGAGQVVIGHDMRDSSP
CCCCHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
TLAAAFAAGVTGQGLDVVRIGLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAG
HHHHHHHHCCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCEEECCCCCCHHCHHHHHHCC
ARPVGADSGLRTIADDVIAGVEDYDGPPGSVGDRDVLADYGRFLRSLVDTSGLRPLRVAV
CCCCCCCCCHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
DAGNGMAGLTTPAVLGPIESITLAPLYFELDGSFPHHEANPLDPANLVDLQAYVRETGAD
ECCCCCCCCCCCHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
IGLAFDGDADRCFVVDERGNPVSPSTVTSLVAARELGREIGATIIHNVITSRAVPELVSE
EEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGGTPLRSRVGHSYIKALMADTGAIFGGEHSAHYYFRDFWGADSGMLAALYVLAALGEQD
CCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEHHHCCCCCHHHHHHHHHHHHCCCC
RPLSELTADYQRYESSGEINFTVADAGQCTEAVLRSFGTRIHSLDHVDGVTVDLGDGSWF
CCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEE
NLRSSNTEPLLRLNVEGRTAEDVAAVVAQISAEIAAITAGTTTEADAGAAP
EECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SRPAATVHRVVKAYDVRGLVGEELDQPLVADLGAAFAKVMRAEGAGQVVIGHDMRDSSP
CCCHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
TLAAAFAAGVTGQGLDVVRIGLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAG
HHHHHHHHCCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCEEECCCCCCHHCHHHHHHCC
ARPVGADSGLRTIADDVIAGVEDYDGPPGSVGDRDVLADYGRFLRSLVDTSGLRPLRVAV
CCCCCCCCCHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
DAGNGMAGLTTPAVLGPIESITLAPLYFELDGSFPHHEANPLDPANLVDLQAYVRETGAD
ECCCCCCCCCCCHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
IGLAFDGDADRCFVVDERGNPVSPSTVTSLVAARELGREIGATIIHNVITSRAVPELVSE
EEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGGTPLRSRVGHSYIKALMADTGAIFGGEHSAHYYFRDFWGADSGMLAALYVLAALGEQD
CCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEHHHCCCCCHHHHHHHHHHHHCCCC
RPLSELTADYQRYESSGEINFTVADAGQCTEAVLRSFGTRIHSLDHVDGVTVDLGDGSWF
CCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEE
NLRSSNTEPLLRLNVEGRTAEDVAAVVAQISAEIAAITAGTTTEADAGAAP
EECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280 [H]