Click here to switch to the map view.

The map label for this gene is kefB

Identifier: 41409447

GI number: 41409447

Start: 3717881

End: 3719029

Strand: Reverse

Name: kefB

Synonym: MAP3349c

Alternate gene names: 41409447

Gene position: 3719029-3717881 (Counterclockwise)

Preceding gene: 41409448

Following gene: 41409445

Centisome position: 77.0

GC content: 71.98

Gene sequence:

>1149_bases
GTGCAGATTTCGGGGACGCTGCTACTGCAACTCGGCGCCCTCCTGGCCACTCTGGCCGTATTGGGCGCCGCCGCGCGCCG
ATTCGCGTTGTCGCCCATCCCCGTCTACCTGCTGGCGGGCCTGGCGCTGGGCAAGGGCGGGCTGCTGCCGCTGGCCACCG
GCGGGCAGTTCATCACCACCAGCGCGCCCATCGGCGTGGTGTTGCTGCTGCTGACCCTGGGCTGCGAGTTCTCCCTCGCC
GAATTCTCCAGCAGCATGCGGCACCACTTGCCGTCCGCGGCGGTCGACGTCGTGCTGAACGCCGCGCCCGGCGCGATCGC
CGGCTGGCTGCTGGGACTGGACGGGGTGGCCATCCTGTGCCTGGCCGGCGTCACCTACATCTCCTCGTCGGGCGTCGTCG
CCCGGCTGCTGGAGGACCTGCACCGGCTCGGTAACCGGGAGACCCCGGCGGTGCTGTCGGTGCTGGTGCTCGAGGACTTC
GCGATGGCCGCCTACCTGCCGCTGTTCGCGGTGCTGGCGTCCGGCGGCGGCTGGCTGCACGCCGTCGTTGGCATGGTGGT
GGCGGTGAGCGCGCTGGTGGCGGCGTTCGCCGCGTCCTACCGCTGGGGTCACCACGTGCAGCGGCTGGTCGAACATCCCG
ACTCCGAACAGCTGATGCTGCGGGTGCTCGGCATCACCCTGATCGTGGCGGCCATGGCCGAATCCCTGCACGCCTCGGCC
GCGGTGGGTGCGTTCCTGGTGGGCCTGACGCTGACCGGGGAGACCGCGACCCGGACCCGTCAGGTGCTGGCGCCGCTGCG
GGATCTGTTCGCCGCCATCTTCTTTCTGGCGATCGGCTACTCGGTGGATCCGCACGAGCTGATCCCGATGCTGCCCGCGG
CGCTGATCCTGGCCGCCGCGACCGCGGCGACCAAGGTGGCCACCGGGATCTTCGCCGCCCGGCACGACGGGGTGGCGCGG
CGCGGGCAGTTGCGGGCGGGCACCGCGCTGATCGCCCGCGGCGAATTCTCGTTGATCATCATCGGATTGGCCGGCAGCTC
GCTGCCCGCGGTCGCGGCGCTGGCGACGTCCTACGTTTTCATCATGGCGATCGCGGGGCCGGTGCTCGCCCGCTACACCG
GCCCGCGGCCGGCCGCACCGGCGACCTGA

Upstream 100 bases:

>100_bases
GGTCCCTCCGAGATGTTGCATGCCCGCGACGTTCTGATCGTGATCGGCACCGAAGACGGTATCGCCGGCGTCGAGAAGAT
CATCGACAAGGGCTGAGCCG

Downstream 100 bases:

>100_bases
GGGCGCGCCCGGTTCACCCGATGTGCAGGGCCACCACCATCCACCGGGTCCCGCCGGCGCCGGGCACCTGCTCGACCCGG
CAGGCGATGGCGTGCATCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQISGTLLLQLGALLATLAVLGAAARRFALSPIPVYLLAGLALGKGGLLPLATGGQFITTSAPIGVVLLLLTLGCEFSLA
EFSSSMRHHLPSAAVDVVLNAAPGAIAGWLLGLDGVAILCLAGVTYISSSGVVARLLEDLHRLGNRETPAVLSVLVLEDF
AMAAYLPLFAVLASGGGWLHAVVGMVVAVSALVAAFAASYRWGHHVQRLVEHPDSEQLMLRVLGITLIVAAMAESLHASA
AVGAFLVGLTLTGETATRTRQVLAPLRDLFAAIFFLAIGYSVDPHELIPMLPAALILAAATAATKVATGIFAARHDGVAR
RGQLRAGTALIARGEFSLIIIGLAGSSLPAVAALATSYVFIMAIAGPVLARYTGPRPAAPAT

Sequences:

>Translated_382_residues
MQISGTLLLQLGALLATLAVLGAAARRFALSPIPVYLLAGLALGKGGLLPLATGGQFITTSAPIGVVLLLLTLGCEFSLA
EFSSSMRHHLPSAAVDVVLNAAPGAIAGWLLGLDGVAILCLAGVTYISSSGVVARLLEDLHRLGNRETPAVLSVLVLEDF
AMAAYLPLFAVLASGGGWLHAVVGMVVAVSALVAAFAASYRWGHHVQRLVEHPDSEQLMLRVLGITLIVAAMAESLHASA
AVGAFLVGLTLTGETATRTRQVLAPLRDLFAAIFFLAIGYSVDPHELIPMLPAALILAAATAATKVATGIFAARHDGVAR
RGQLRAGTALIARGEFSLIIIGLAGSSLPAVAALATSYVFIMAIAGPVLARYTGPRPAAPAT
>Mature_382_residues
MQISGTLLLQLGALLATLAVLGAAARRFALSPIPVYLLAGLALGKGGLLPLATGGQFITTSAPIGVVLLLLTLGCEFSLA
EFSSSMRHHLPSAAVDVVLNAAPGAIAGWLLGLDGVAILCLAGVTYISSSGVVARLLEDLHRLGNRETPAVLSVLVLEDF
AMAAYLPLFAVLASGGGWLHAVVGMVVAVSALVAAFAASYRWGHHVQRLVEHPDSEQLMLRVLGITLIVAAMAESLHASA
AVGAFLVGLTLTGETATRTRQVLAPLRDLFAAIFFLAIGYSVDPHELIPMLPAALILAAATAATKVATGIFAARHDGVAR
RGQLRAGTALIARGEFSLIIIGLAGSSLPAVAALATSYVFIMAIAGPVLARYTGPRPAAPAT

Specific function: Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of khtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=344, Percent_Identity=30.5232558139535, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 39118; Mature: 39118

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISGTLLLQLGALLATLAVLGAAARRFALSPIPVYLLAGLALGKGGLLPLATGGQFITT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEC
SAPIGVVLLLLTLGCEFSLAEFSSSMRHHLPSAAVDVVLNAAPGAIAGWLLGLDGVAILC
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LAGVTYISSSGVVARLLEDLHRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLASGGGWLH
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AVVGMVVAVSALVAAFAASYRWGHHVQRLVEHPDSEQLMLRVLGITLIVAAMAESLHASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGAFLVGLTLTGETATRTRQVLAPLRDLFAAIFFLAIGYSVDPHELIPMLPAALILAAA
HHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TAATKVATGIFAARHDGVARRGQLRAGTALIARGEFSLIIIGLAGSSLPAVAALATSYVF
HHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEECCCEEEEEEEECCCCHHHHHHHHHHHHH
IMAIAGPVLARYTGPRPAAPAT
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQISGTLLLQLGALLATLAVLGAAARRFALSPIPVYLLAGLALGKGGLLPLATGGQFITT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEC
SAPIGVVLLLLTLGCEFSLAEFSSSMRHHLPSAAVDVVLNAAPGAIAGWLLGLDGVAILC
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LAGVTYISSSGVVARLLEDLHRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLASGGGWLH
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AVVGMVVAVSALVAAFAASYRWGHHVQRLVEHPDSEQLMLRVLGITLIVAAMAESLHASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGAFLVGLTLTGETATRTRQVLAPLRDLFAAIFFLAIGYSVDPHELIPMLPAALILAAA
HHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TAATKVATGIFAARHDGVARRGQLRAGTALIARGEFSLIIIGLAGSSLPAVAALATSYVF
HHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEECCCEEEEEEEECCCCHHHHHHHHHHHHH
IMAIAGPVLARYTGPRPAAPAT
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]