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The map label for this gene is ucpA [H]

Identifier: 41409423

GI number: 41409423

Start: 3693954

End: 3694802

Strand: Direct

Name: ucpA [H]

Synonym: MAP3325

Alternate gene names: 41409423

Gene position: 3693954-3694802 (Clockwise)

Preceding gene: 41409418

Following gene: 41409428

Centisome position: 76.48

GC content: 67.14

Gene sequence:

>849_bases
ATGTCCCTGAATGGCAAGACCATGTTCATCTCCGGCGCCAGTCGCGGAATCGGCCTCGCGATCGCCAAGCGCGCCGCCCA
GGACGGCGCCAACATCGCGCTGATCGCCAAGACGGCCGAGCCGCACCCGAAGCTGCCGGGGACGGTGTACACGGCGGCCA
AGGAGCTCGAGGAAGCGGGCGGACAGGCGTTGCCGATCGTGGGCGACGTCCGCGACCCGGAGTCGGTGGAGGCCGCCGTC
GCCAAGACCATCGAGCAGTTCGGCGGTATCGACATCTGCGTCAACAACGCCTCGGCGATCAACCTGGGTTCCATCACCGA
GGTGCCGATGAAGCGGTTCGACCTGATGAACGGCATCCAGGTGCGCGGCACCTACGCGGTGTCGCAGGCGTGCATCCCGC
ACCTGAAGGGCCGGGAGAACCCGCACATCCTGACGCTGTCGCCGCCGGTGCTGCTCGGCAAGGAGTGGTTGGAGCCGACG
GCCTATATGATGGCCAAATTCGGTATGACGTTGTGCGCGTTGGGCATCGCCGAGGAGATGCGCGAAGCCGGCATCGCCTC
GAACACGCTGTGGCCGCGCACGCTGGTGGCGACGGCCGCGGTGCAGAACCTGCTCGGCGGGGACGAGGCGATGGGCCGGG
CCCGCAAGCCCGAGGTGTATTCGGACGCCGCCTACGTCATCCTCAACAAGCCGGCCCGCGAGTTCACCGGCAACATGCTG
CTGTGCGAGGACGTGCTGGTGGAATCCGGTGTCACCGACCTGTCGGTGTACAACTGCGTGCCGGGATCCCAACTGGGCGT
GGACTTTTGGGTGGACGGCGTCAACCCGCCGGGATACACCGGCCCCTAG

Upstream 100 bases:

>100_bases
CGGGCTATTTCCCGCCGGTTTCCGGCCGCATTTCCCGCGGCTTTCCGGGCCCGATCAGACCCCGATCGGACCGGATCCGC
CGTGGCGTTAGTGTGACGCC

Downstream 100 bases:

>100_bases
CAACGCCCGTTCGTAGGCCGGTCAGCAGAAGGTGACGACGACCTTGTCGGCGGCGCCGGGAGTACGGGCCAGTTCGAGCG
CCTCGCCGACGCGGTCGAAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPKLPGTVYTAAKELEEAGGQALPIVGDVRDPESVEAAV
AKTIEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHLKGRENPHILTLSPPVLLGKEWLEPT
AYMMAKFGMTLCALGIAEEMREAGIASNTLWPRTLVATAAVQNLLGGDEAMGRARKPEVYSDAAYVILNKPAREFTGNML
LCEDVLVESGVTDLSVYNCVPGSQLGVDFWVDGVNPPGYTGP

Sequences:

>Translated_282_residues
MSLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPKLPGTVYTAAKELEEAGGQALPIVGDVRDPESVEAAV
AKTIEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHLKGRENPHILTLSPPVLLGKEWLEPT
AYMMAKFGMTLCALGIAEEMREAGIASNTLWPRTLVATAAVQNLLGGDEAMGRARKPEVYSDAAYVILNKPAREFTGNML
LCEDVLVESGVTDLSVYNCVPGSQLGVDFWVDGVNPPGYTGP
>Mature_281_residues
SLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPKLPGTVYTAAKELEEAGGQALPIVGDVRDPESVEAAVA
KTIEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHLKGRENPHILTLSPPVLLGKEWLEPTA
YMMAKFGMTLCALGIAEEMREAGIASNTLWPRTLVATAAVQNLLGGDEAMGRARKPEVYSDAAYVILNKPAREFTGNMLL
CEDVLVESGVTDLSVYNCVPGSQLGVDFWVDGVNPPGYTGP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254986, Length=271, Percent_Identity=52.0295202952029, Blast_Score=275, Evalue=3e-74,
Organism=Homo sapiens, GI209862901, Length=221, Percent_Identity=27.1493212669683, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI19923983, Length=221, Percent_Identity=27.1493212669683, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4504505, Length=195, Percent_Identity=26.1538461538462, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=192, Percent_Identity=33.8541666666667, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=26.4822134387352, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=268, Percent_Identity=50.7462686567164, Blast_Score=287, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI17558628, Length=268, Percent_Identity=52.9850746268657, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17544670, Length=280, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=214, Percent_Identity=26.6355140186916, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=232, Percent_Identity=27.5862068965517, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357673, Length=278, Percent_Identity=51.4388489208633, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI23397609, Length=135, Percent_Identity=34.0740740740741, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=27.0833333333333, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355319, Length=217, Percent_Identity=27.1889400921659, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29813; Mature: 29681

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPKLPGTVYTAAKELEEAG
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
GQALPIVGDVRDPESVEAAVAKTIEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQ
CCEECEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCHHHHHHHHHHCCEE
VRGTYAVSQACIPHLKGRENPHILTLSPPVLLGKEWLEPTAYMMAKFGMTLCALGIAEEM
EEEEHHHHHHHHHHHCCCCCCEEEEECCCHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHH
REAGIASNTLWPRTLVATAAVQNLLGGDEAMGRARKPEVYSDAAYVILNKPAREFTGNML
HHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEEEECCCHHHHCCCEE
LCEDVLVESGVTDLSVYNCVPGSQLGVDFWVDGVNPPGYTGP
EHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPKLPGTVYTAAKELEEAG
CCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
GQALPIVGDVRDPESVEAAVAKTIEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQ
CCEECEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCHHHHHHHHHHCCEE
VRGTYAVSQACIPHLKGRENPHILTLSPPVLLGKEWLEPTAYMMAKFGMTLCALGIAEEM
EEEEHHHHHHHHHHHCCCCCCEEEEECCCHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHH
REAGIASNTLWPRTLVATAAVQNLLGGDEAMGRARKPEVYSDAAYVILNKPAREFTGNML
HHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEEEECCCHHHHCCCEE
LCEDVLVESGVTDLSVYNCVPGSQLGVDFWVDGVNPPGYTGP
EHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]