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The map label for this gene is moeZ

Identifier: 41409404

GI number: 41409404

Start: 3676994

End: 3678190

Strand: Reverse

Name: moeZ

Synonym: MAP3306c

Alternate gene names: 41409404

Gene position: 3678190-3676994 (Counterclockwise)

Preceding gene: 41409405

Following gene: 41409403

Centisome position: 76.16

GC content: 71.09

Gene sequence:

>1197_bases
GTGTCCACGCCGCTGCCGCCGCTGGTGGCGCCCGCAGACCAGCTGACCGCCGACGAGATGGCCCGCTACAGCCGGCAGCT
GATCATCCCCGGCCTTGGCGTCGACGGGCAGAAGCGGCTCAAGAACGCCCGGGTGCTGGTGATCGGGGCCGGCGGGCTGG
GCGCGCCGACGCTGCTCTACCTGGCCGCGGCCGGGGTGGGCACCATCGGCATCGTCGAGTTCGACGCGGTCGAGGAGTCC
AACCTGCAGCGCCAGATCATTCACGGGGTGGCCGACGTCGGGCGGTCCAAGGCCGCCTCGGCGCGCGACTCGATCGCCGC
GATCAACCCGCTGGTCGACGTGCGGCTGCACGAGTTCCGGCTGGACGCGTCCAACGCCGTCGAGCTGTTCGGCCACTACG
ACCTGATCGTCGACGGCACCGACAACTTCGCCACCCGCTACCTGATCAACGACGCGGCGGTGCTGGCCGGCAAGCCGTAC
GTGTGGGGGTCCATCTACCGGTTCGAGGGCCAGGTCTCGGTGTGCTGGGAGGACGCCCCGGACGGCCGCGGACTCAACTA
CCGCGACCTCTACCCCGAACCCCCGCCGCCCGGCGCGGTCCCGTCCTGCGCCGAGGGCGGGGTGCTGGGCGTCGTCTGCG
CCTCCATCGCCTCGGTGATGAGCACCGAGGCGATCAAACTCATCACCGGGATCGGCGAATCCCTGCTGGGCCGGTTGATG
ATCTACGACGCGCTCGAGATGAGCTATCGCACCATCGCGATCCGCCGCGACCCCTGCGACGCGTCGCGGCCCGCCATCAC
CACGCTGGTCGACTACGAGCAGCTGTGCGGCGCCGCGCCGGCCGCCTCCACCGACGCCGCCACCGGCGGGGCCGAGGCGG
CCATCACCCCGCGGCAGCTGCGCGAGCTGCTGGACTCCGGCGCCAAGCTGGCGCTGATCGACGTGCGCGAACCGGTGGAG
TTCGACATCGTGCACCTCGACGGCGCGCAGCTGATCCCGCAGTCGTCGATCAACTCCGGGGAGGGCCTGGCAAAGCTGCC
GGCCGACCGCATGCCGGTGCTGTACTGCAAGACCGGGGTGCGGTCGGCCCAGGCGTTGGCGGTGGTGCGCCAGGCCGGAT
TCAGCGACGCGGTGCATCTGCAGGGCGGGATCGTGGCCTGGGCGCAACAGATGCAGCCCGACATGATCCTGTACTGA

Upstream 100 bases:

>100_bases
GATCGCCTAGCGGCCTCGTTGCCGCGCCGTGGGCGGGCTGCTGTGATGGTGGTAGACGGCTCGAATCGCTGAGCCGACCG
ACCTGCAGGAGACGTTTCCC

Downstream 100 bases:

>100_bases
CCAACCCGCTTGTTGGACTCGTTTAGAGTACCGGTGTGACAGTCGAGCCACCGCCGGATCATGTGTTGTCGGCGTTCGGT
TTGGCCGGCGTTAAACCCGT

Product: molybdopterin biosynthesis-like protein MoeZ

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSTPLPPLVAPADQLTADEMARYSRQLIIPGLGVDGQKRLKNARVLVIGAGGLGAPTLLYLAAAGVGTIGIVEFDAVEES
NLQRQIIHGVADVGRSKAASARDSIAAINPLVDVRLHEFRLDASNAVELFGHYDLIVDGTDNFATRYLINDAAVLAGKPY
VWGSIYRFEGQVSVCWEDAPDGRGLNYRDLYPEPPPPGAVPSCAEGGVLGVVCASIASVMSTEAIKLITGIGESLLGRLM
IYDALEMSYRTIAIRRDPCDASRPAITTLVDYEQLCGAAPAASTDAATGGAEAAITPRQLRELLDSGAKLALIDVREPVE
FDIVHLDGAQLIPQSSINSGEGLAKLPADRMPVLYCKTGVRSAQALAVVRQAGFSDAVHLQGGIVAWAQQMQPDMILY

Sequences:

>Translated_398_residues
MSTPLPPLVAPADQLTADEMARYSRQLIIPGLGVDGQKRLKNARVLVIGAGGLGAPTLLYLAAAGVGTIGIVEFDAVEES
NLQRQIIHGVADVGRSKAASARDSIAAINPLVDVRLHEFRLDASNAVELFGHYDLIVDGTDNFATRYLINDAAVLAGKPY
VWGSIYRFEGQVSVCWEDAPDGRGLNYRDLYPEPPPPGAVPSCAEGGVLGVVCASIASVMSTEAIKLITGIGESLLGRLM
IYDALEMSYRTIAIRRDPCDASRPAITTLVDYEQLCGAAPAASTDAATGGAEAAITPRQLRELLDSGAKLALIDVREPVE
FDIVHLDGAQLIPQSSINSGEGLAKLPADRMPVLYCKTGVRSAQALAVVRQAGFSDAVHLQGGIVAWAQQMQPDMILY
>Mature_397_residues
STPLPPLVAPADQLTADEMARYSRQLIIPGLGVDGQKRLKNARVLVIGAGGLGAPTLLYLAAAGVGTIGIVEFDAVEESN
LQRQIIHGVADVGRSKAASARDSIAAINPLVDVRLHEFRLDASNAVELFGHYDLIVDGTDNFATRYLINDAAVLAGKPYV
WGSIYRFEGQVSVCWEDAPDGRGLNYRDLYPEPPPPGAVPSCAEGGVLGVVCASIASVMSTEAIKLITGIGESLLGRLMI
YDALEMSYRTIAIRRDPCDASRPAITTLVDYEQLCGAAPAASTDAATGGAEAAITPRQLRELLDSGAKLALIDVREPVEF
DIVHLDGAQLIPQSSINSGEGLAKLPADRMPVLYCKTGVRSAQALAVVRQAGFSDAVHLQGGIVAWAQQMQPDMILY

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=418, Percent_Identity=39.2344497607655, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI4885649, Length=145, Percent_Identity=32.4137931034483, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1787048, Length=247, Percent_Identity=38.8663967611336, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI87082356, Length=241, Percent_Identity=36.5145228215768, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17540406, Length=413, Percent_Identity=37.772397094431, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI193203301, Length=141, Percent_Identity=29.7872340425532, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71984476, Length=134, Percent_Identity=32.8358208955224, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321903, Length=396, Percent_Identity=36.3636363636364, Blast_Score=215, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6322639, Length=215, Percent_Identity=25.1162790697674, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320598, Length=140, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325438, Length=127, Percent_Identity=28.3464566929134, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24582879, Length=403, Percent_Identity=39.7022332506204, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24660640, Length=171, Percent_Identity=30.9941520467836, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573937, Length=192, Percent_Identity=27.0833333333333, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42160; Mature: 42029

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPLPPLVAPADQLTADEMARYSRQLIIPGLGVDGQKRLKNARVLVIGAGGLGAPTLLY
CCCCCCCCCCCHHHCCHHHHHHHHCEEEECCCCCCHHHHHCCCEEEEEECCCCCHHHHHH
LAAAGVGTIGIVEFDAVEESNLQRQIIHGVADVGRSKAASARDSIAAINPLVDVRLHEFR
HHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHCCHHHHCCHHHEEEEEEE
LDASNAVELFGHYDLIVDGTDNFATRYLINDAAVLAGKPYVWGSIYRFEGQVSVCWEDAP
CCCCHHEEEEECEEEEEECCCCCEEEEEECCCCEECCCCCEEEEEEEECCEEEEEECCCC
DGRGLNYRDLYPEPPPPGAVPSCAEGGVLGVVCASIASVMSTEAIKLITGIGESLLGRLM
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IYDALEMSYRTIAIRRDPCDASRPAITTLVDYEQLCGAAPAASTDAATGGAEAAITPRQL
HHHHHHCCEEEEEEEECCCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
RELLDSGAKLALIDVREPVEFDIVHLDGAQLIPQSSINSGEGLAKLPADRMPVLYCKTGV
HHHHHCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCC
RSAQALAVVRQAGFSDAVHLQGGIVAWAQQMQPDMILY
CHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCEECC
>Mature Secondary Structure 
STPLPPLVAPADQLTADEMARYSRQLIIPGLGVDGQKRLKNARVLVIGAGGLGAPTLLY
CCCCCCCCCCHHHCCHHHHHHHHCEEEECCCCCCHHHHHCCCEEEEEECCCCCHHHHHH
LAAAGVGTIGIVEFDAVEESNLQRQIIHGVADVGRSKAASARDSIAAINPLVDVRLHEFR
HHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHCCHHHHCCHHHEEEEEEE
LDASNAVELFGHYDLIVDGTDNFATRYLINDAAVLAGKPYVWGSIYRFEGQVSVCWEDAP
CCCCHHEEEEECEEEEEECCCCCEEEEEECCCCEECCCCCEEEEEEEECCEEEEEECCCC
DGRGLNYRDLYPEPPPPGAVPSCAEGGVLGVVCASIASVMSTEAIKLITGIGESLLGRLM
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IYDALEMSYRTIAIRRDPCDASRPAITTLVDYEQLCGAAPAASTDAATGGAEAAITPRQL
HHHHHHCCEEEEEEEECCCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
RELLDSGAKLALIDVREPVEFDIVHLDGAQLIPQSSINSGEGLAKLPADRMPVLYCKTGV
HHHHHCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCC
RSAQALAVVRQAGFSDAVHLQGGIVAWAQQMQPDMILY
CHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]