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The map label for this gene is narL_2

Identifier: 41409373

GI number: 41409373

Start: 3635052

End: 3635717

Strand: Direct

Name: narL_2

Synonym: MAP3275

Alternate gene names: 41409373

Gene position: 3635052-3635717 (Clockwise)

Preceding gene: 41409372

Following gene: 41409377

Centisome position: 75.26

GC content: 70.12

Gene sequence:

>666_bases
ATGACGGATGACGCGACGCCCACGACGGTGATGGTGGTCGACGACCATCCGATCTGGCGTGACGCGGTGGCTCGCGACCT
GGCCGAAAGCGGCTTCGCGGTGGTCGCTACCGCCGACGGGGTGACCGCCGCCCAGCGGCGGGCGGGCGTGGTCAGGCCCG
ATGTGGTGGTGATGGACATGCAGCTGCCCGACGGTGACGGTGCGCAGGCCACCGCCGCGGTGCTGGCGGTCTCGCCCTCG
TCGCGGGTGCTGGTGCTGTCGGCCTCCGACGAACGCGACGACGTCCTGCAGGCGGTCAAGGCCGGTGCGGCCGGCTACCT
GGTGAAGAGCGCCTCGAAAGCCGAACTGGCGCAGGCGGTGACGGACACCGCCGCCGGGCGGGCCGTGTTCACCCCGAGCC
TGGCCGGGCTGGTGCTGGGCGAATACCGGCGCATCGCGCAGAGCAAGGACGACGGCCCCACCCGCCCCCGGCTCACCGAC
CGCGAGACGGAGGTGTTGCGGTATGTCGCAAAAGGGCTGTCCGCCAAGCAGATCGCCGAGAAGCTCTCGCTGAGCCACCG
CACGGTGGAAAACCATGTGCAGGCGACGTTTCGCAAACTGCAGGTCGCCAACCGGGTGGAATTGGCCCGCTACGCCATCG
AACACGGCCTCGACGAAGAGCCGTGA

Upstream 100 bases:

>100_bases
GTGGGACGGTTGGCGTCGCTGGGCGGCACCGCCGAACTGCACAGCGAGCCCGGGGCCGGCACCGAATGGGAGTTGTGCGT
GCCGCGCCGGGAGGGACGCG

Downstream 100 bases:

>100_bases
CCCGCGGGGCCGGCGTGCTGGGCCACGATCCGCGCGGCCACCAGCGCGGCCACCACCACGGCCATGCAGACCAGCCCGTC
GTCCTTGAGCCCCCACCTGA

Product: NarL_2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTDDATPTTVMVVDDHPIWRDAVARDLAESGFAVVATADGVTAAQRRAGVVRPDVVVMDMQLPDGDGAQATAAVLAVSPS
SRVLVLSASDERDDVLQAVKAGAAGYLVKSASKAELAQAVTDTAAGRAVFTPSLAGLVLGEYRRIAQSKDDGPTRPRLTD
RETEVLRYVAKGLSAKQIAEKLSLSHRTVENHVQATFRKLQVANRVELARYAIEHGLDEEP

Sequences:

>Translated_221_residues
MTDDATPTTVMVVDDHPIWRDAVARDLAESGFAVVATADGVTAAQRRAGVVRPDVVVMDMQLPDGDGAQATAAVLAVSPS
SRVLVLSASDERDDVLQAVKAGAAGYLVKSASKAELAQAVTDTAAGRAVFTPSLAGLVLGEYRRIAQSKDDGPTRPRLTD
RETEVLRYVAKGLSAKQIAEKLSLSHRTVENHVQATFRKLQVANRVELARYAIEHGLDEEP
>Mature_220_residues
TDDATPTTVMVVDDHPIWRDAVARDLAESGFAVVATADGVTAAQRRAGVVRPDVVVMDMQLPDGDGAQATAAVLAVSPSS
RVLVLSASDERDDVLQAVKAGAAGYLVKSASKAELAQAVTDTAAGRAVFTPSLAGLVLGEYRRIAQSKDDGPTRPRLTDR
ETEVLRYVAKGLSAKQIAEKLSLSHRTVENHVQATFRKLQVANRVELARYAIEHGLDEEP

Specific function: Probable member of the two-component regulatory system NarS/NarL [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=205, Percent_Identity=35.609756097561, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786747, Length=210, Percent_Identity=32.3809523809524, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788222, Length=210, Percent_Identity=30.4761904761905, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787473, Length=208, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790102, Length=208, Percent_Identity=34.6153846153846, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788712, Length=202, Percent_Identity=23.7623762376238, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788546, Length=207, Percent_Identity=25.1207729468599, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23528; Mature: 23397

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDDATPTTVMVVDDHPIWRDAVARDLAESGFAVVATADGVTAAQRRAGVVRPDVVVMDM
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCEEEEEE
QLPDGDGAQATAAVLAVSPSSRVLVLSASDERDDVLQAVKAGAAGYLVKSASKAELAQAV
ECCCCCCCHHEEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHH
TDTAAGRAVFTPSLAGLVLGEYRRIAQSKDDGPTRPRLTDRETEVLRYVAKGLSAKQIAE
HHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
KLSLSHRTVENHVQATFRKLQVANRVELARYAIEHGLDEEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDDATPTTVMVVDDHPIWRDAVARDLAESGFAVVATADGVTAAQRRAGVVRPDVVVMDM
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCEEEEEE
QLPDGDGAQATAAVLAVSPSSRVLVLSASDERDDVLQAVKAGAAGYLVKSASKAELAQAV
ECCCCCCCHHEEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHH
TDTAAGRAVFTPSLAGLVLGEYRRIAQSKDDGPTRPRLTDRETEVLRYVAKGLSAKQIAE
HHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
KLSLSHRTVENHVQATFRKLQVANRVELARYAIEHGLDEEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]