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The map label for this gene is fadB4

Identifier: 41409288

GI number: 41409288

Start: 3540935

End: 3541906

Strand: Direct

Name: fadB4

Synonym: MAP3190

Alternate gene names: 41409288

Gene position: 3540935-3541906 (Clockwise)

Preceding gene: 41409287

Following gene: 41409289

Centisome position: 73.31

GC content: 73.25

Gene sequence:

>972_bases
ATGCGTGCTGCACGAGTGACTCGACTGGACGGTCCGGACGCGATCGAGGTGACGGACGTCGACGAACCGACCGGCGACGG
CGTCTTCGTCGACGTGCACGCGGCCGGGGTGGCCTTCCCGGACGCCCTGCTCACCCGCGGCCTCTACCAGTACCGGCCGG
AGTTGCCGTTCGTGCTCGGCGCCGAGATCGCCGGCGTGGTGCGGTCCGCGCCCGAGGGCGCGCACGTGCGTTCCGGCGAC
CGGGTCGTCGGCCTCACCATGCTGTCCGGCGGCATGGCCGAGGTGGCGGTGCTGGCCCCCGACCGGGTGTTCAAGCTGCC
CGACAAGGTCAGCTTCGAGGCCGGCGCCGGCCTGCTGTTCAACGACCTGACGGTGTACTTCGCGCTGACCGTGCGGGGCC
GGCTGCAGCGCGGCGAGACGGTGCTGGTGCACGGCGCGGCCGGCGGTATCGGCACCTCGGCGCTGCGACTGGCGCCGGCG
CTGGGCGCCGCCCGCACCATCGCCGTGGTCAGCACGACGGACAAGGCCGACATCGCCACGGCGGCCGGCGCGACGGACGT
CGTGCTGGCCGACGGCTTCAAGGACGCCGTGAAGGAGCTGACCCACGGCCGCGGCGTCGACATCGTCGTCGACCCGGTCG
GCGGCGACCGGTTCACCGATTCGCTGCGCTCGCTGGCCCCCGGCGGGCGGCTGCTGGTGGTCGGCTTCACCGGCGGCGAG
ATCCCCACGGTCAAGGTAAACCGGTTGCTACTCAACAACATCGACGTGGTCGGCGTCGGCTGGGGCGCCTGGACGGGCAC
CCATCCCGGCGCGCTGGCCGAGCAGTGGGCGGGGCTCGAGCGACTGCTCACCTCCGGTGAGCTGGCCCCGCCCGAGCCGG
TGGTCTATCCGCTCGACGAGGCCGCGGCGGCCGTGGCCTCGCTGGAGAACCGCACCGCCAAGGGCAAGGTCGTGTTGCGC
GTGCGCGGTTAG

Upstream 100 bases:

>100_bases
AGTACACGTTCGGCGACAGTCAAGCGCGCCGGCGAATCCTCCGGCCGGGCCGTGGTGCGGGTCGTCGACGGTTTTTGAGC
CGGCAGTACGCTGTTCGACC

Downstream 100 bases:

>100_bases
GCGCTCGGCGCCGGCGGCACCCGGGCGGGCCTTGTGCCCGCCCAAAAGAAAAAGTAATGTCACTTTCAGTTTTTGCCGCC
GAGCTTGGCCCCACCGGAGG

Product: FadB4

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MRAARVTRLDGPDAIEVTDVDEPTGDGVFVDVHAAGVAFPDALLTRGLYQYRPELPFVLGAEIAGVVRSAPEGAHVRSGD
RVVGLTMLSGGMAEVAVLAPDRVFKLPDKVSFEAGAGLLFNDLTVYFALTVRGRLQRGETVLVHGAAGGIGTSALRLAPA
LGAARTIAVVSTTDKADIATAAGATDVVLADGFKDAVKELTHGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGGE
IPTVKVNRLLLNNIDVVGVGWGAWTGTHPGALAEQWAGLERLLTSGELAPPEPVVYPLDEAAAAVASLENRTAKGKVVLR
VRG

Sequences:

>Translated_323_residues
MRAARVTRLDGPDAIEVTDVDEPTGDGVFVDVHAAGVAFPDALLTRGLYQYRPELPFVLGAEIAGVVRSAPEGAHVRSGD
RVVGLTMLSGGMAEVAVLAPDRVFKLPDKVSFEAGAGLLFNDLTVYFALTVRGRLQRGETVLVHGAAGGIGTSALRLAPA
LGAARTIAVVSTTDKADIATAAGATDVVLADGFKDAVKELTHGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGGE
IPTVKVNRLLLNNIDVVGVGWGAWTGTHPGALAEQWAGLERLLTSGELAPPEPVVYPLDEAAAAVASLENRTAKGKVVLR
VRG
>Mature_323_residues
MRAARVTRLDGPDAIEVTDVDEPTGDGVFVDVHAAGVAFPDALLTRGLYQYRPELPFVLGAEIAGVVRSAPEGAHVRSGD
RVVGLTMLSGGMAEVAVLAPDRVFKLPDKVSFEAGAGLLFNDLTVYFALTVRGRLQRGETVLVHGAAGGIGTSALRLAPA
LGAARTIAVVSTTDKADIATAAGATDVVLADGFKDAVKELTHGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGGE
IPTVKVNRLLLNNIDVVGVGWGAWTGTHPGALAEQWAGLERLLTSGELAPPEPVVYPLDEAAAAVASLENRTAKGKVVLR
VRG

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=328, Percent_Identity=30.7926829268293, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI13236495, Length=328, Percent_Identity=30.7926829268293, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI18379349, Length=307, Percent_Identity=31.5960912052117, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI194239676, Length=191, Percent_Identity=35.6020942408377, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI41872631, Length=320, Percent_Identity=28.4375, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI24308257, Length=322, Percent_Identity=27.3291925465839, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI67078404, Length=308, Percent_Identity=26.9480519480519, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI22538446, Length=334, Percent_Identity=25.4491017964072, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI22538444, Length=334, Percent_Identity=25.4491017964072, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI67078406, Length=285, Percent_Identity=27.3684210526316, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1790485, Length=319, Percent_Identity=34.1692789968652, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789651, Length=277, Percent_Identity=29.2418772563177, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=330, Percent_Identity=31.5151515151515, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17556000, Length=314, Percent_Identity=25.796178343949, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536829, Length=306, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=331, Percent_Identity=29.9093655589124, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221330659, Length=220, Percent_Identity=27.7272727272727, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920632, Length=220, Percent_Identity=27.7272727272727, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24581345, Length=184, Percent_Identity=27.7173913043478, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33406; Mature: 33406

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAARVTRLDGPDAIEVTDVDEPTGDGVFVDVHAAGVAFPDALLTRGLYQYRPELPFVLG
CCCCEEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEC
AEIAGVVRSAPEGAHVRSGDRVVGLTMLSGGMAEVAVLAPDRVFKLPDKVSFEAGAGLLF
HHHHHHHHCCCCCCEECCCCEEEEEEEECCCCEEEEEECCCCEEECCCCCCCCCCCCEEE
NDLTVYFALTVRGRLQRGETVLVHGAAGGIGTSALRLAPALGAARTIAVVSTTDKADIAT
CCEEEEEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHC
AAGATDVVLADGFKDAVKELTHGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGGE
CCCCCEEEEECCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCC
IPTVKVNRLLLNNIDVVGVGWGAWTGTHPGALAEQWAGLERLLTSGELAPPEPVVYPLDE
CCEEEEEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECHH
AAAAVASLENRTAKGKVVLRVRG
HHHHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure
MRAARVTRLDGPDAIEVTDVDEPTGDGVFVDVHAAGVAFPDALLTRGLYQYRPELPFVLG
CCCCEEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEC
AEIAGVVRSAPEGAHVRSGDRVVGLTMLSGGMAEVAVLAPDRVFKLPDKVSFEAGAGLLF
HHHHHHHHCCCCCCEECCCCEEEEEEEECCCCEEEEEECCCCEEECCCCCCCCCCCCEEE
NDLTVYFALTVRGRLQRGETVLVHGAAGGIGTSALRLAPALGAARTIAVVSTTDKADIAT
CCEEEEEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHC
AAGATDVVLADGFKDAVKELTHGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGGE
CCCCCEEEEECCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCC
IPTVKVNRLLLNNIDVVGVGWGAWTGTHPGALAEQWAGLERLLTSGELAPPEPVVYPLDE
CCEEEEEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECHH
AAAAVASLENRTAKGKVVLRVRG
HHHHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]