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The map label for this gene is adhC

Identifier: 41409191

GI number: 41409191

Start: 3441530

End: 3442570

Strand: Direct

Name: adhC

Synonym: MAP3093

Alternate gene names: 41409191

Gene position: 3441530-3442570 (Clockwise)

Preceding gene: 41409190

Following gene: 41409194

Centisome position: 71.26

GC content: 67.53

Gene sequence:

>1041_bases
ATGAGCACCGTTTCGGCGTACGCCGCCACGTCGGCGACCGAACCATTGACCAAGACCACTATCGAGCGGCGCGACCCCGG
CCCGCGCGACGTGGCCATCGACATCAAGTTCGCCGGCATCTGCCACTCCGACATCCACACCGCGAAAGGTGAATGGGGCC
ACACGAATTACCCGGTGGTGGTGGGCCACGAGATCGCCGGCGTCGTCACCGAGGTGGGCGCGGAGGTCACCAAGTACAAG
GTGGGCGACCACGTCGGCGTGGGCTGCATGGTGAACTCCTGCCGGCAGTGCAGCAGCTGTACGGCCGGGCTGGAGCAGTA
CTGCAAGCGCGGCGCGACCTTCACCTACAACTCGATCGACAGGGACGGCTCGGTCACCCAGGGCGGCTACAGCCAGGCGA
TCGTGGTCGACGAGGACTTCGTCGTGCGCATCCCCGACTCGCTGCCGCTGGACAAGGCGGCCCCGCTGCTGTGCGCGGGC
ATCACGCTGTTCTCGCCGCTGCGGCACTGGAACGCCGGGCCCGGCACCCGGTTGGCGATCGTCGGCCTGGGCGGCCTGGG
GCACATGGGCGTCAAGCTGGGTGCGGCGATGGGCGCCGAGGTGACGGTGCTGTCGCAGTCGCTGAAGAAGATGGAGGACG
GGCTGCGGCTGGGCGCCAAGCACTACCACGCCACCGCCGACCCCGACACCTTCACGAAGCTGCGCGGCAGCTTCGACCTG
ATGCTCAACACCGTGTCGGCGAACCTCAAGCTCAACGACTATCTGAGCCTGCTCGACGTCGACGGCACGCTGGTCGAGCT
GGGCATCCCCGAGCACCCGATGGAGGTGGGCGCGTTCCCGCTGGCGCTGGCGCGGCGCAGCCTGTCCGGGTCGAACATCG
GCGGCATCGCCGAGACCCAGGAGATGCTGGACTTCTGCGCCGAGCACAACGTGACGCCGGAGATCGAGCTGATCGAGCCC
GACTACATCAACGAGGCCTACGAGCGCGTGCTGGCCAGCGACGTGCGCTACCGCTTCGTCATCGACATCTCGAAGCTATG
A

Upstream 100 bases:

>100_bases
ATCCCCCACGCGACAACGTGATCTTCGCCGCGCCGGTTGGCGCCAGAACCATTACCTTAGCTAAACTTTTTGGGAAAGCA
CGGCTGGAAGAGGGACATTC

Downstream 100 bases:

>100_bases
GGCTATGAGGCTATGAGCCTATGAGGCGACCCCCGGTGTCTGACCTCGCGCCGCGATCTCGGCGGACTCGGCGAAGTCAT
CACCGGGGATCACCTCGCTG

Product: AdhC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSTVSAYAATSATEPLTKTTIERRDPGPRDVAIDIKFAGICHSDIHTAKGEWGHTNYPVVVGHEIAGVVTEVGAEVTKYK
VGDHVGVGCMVNSCRQCSSCTAGLEQYCKRGATFTYNSIDRDGSVTQGGYSQAIVVDEDFVVRIPDSLPLDKAAPLLCAG
ITLFSPLRHWNAGPGTRLAIVGLGGLGHMGVKLGAAMGAEVTVLSQSLKKMEDGLRLGAKHYHATADPDTFTKLRGSFDL
MLNTVSANLKLNDYLSLLDVDGTLVELGIPEHPMEVGAFPLALARRSLSGSNIGGIAETQEMLDFCAEHNVTPEIELIEP
DYINEAYERVLASDVRYRFVIDISKL

Sequences:

>Translated_346_residues
MSTVSAYAATSATEPLTKTTIERRDPGPRDVAIDIKFAGICHSDIHTAKGEWGHTNYPVVVGHEIAGVVTEVGAEVTKYK
VGDHVGVGCMVNSCRQCSSCTAGLEQYCKRGATFTYNSIDRDGSVTQGGYSQAIVVDEDFVVRIPDSLPLDKAAPLLCAG
ITLFSPLRHWNAGPGTRLAIVGLGGLGHMGVKLGAAMGAEVTVLSQSLKKMEDGLRLGAKHYHATADPDTFTKLRGSFDL
MLNTVSANLKLNDYLSLLDVDGTLVELGIPEHPMEVGAFPLALARRSLSGSNIGGIAETQEMLDFCAEHNVTPEIELIEP
DYINEAYERVLASDVRYRFVIDISKL
>Mature_345_residues
STVSAYAATSATEPLTKTTIERRDPGPRDVAIDIKFAGICHSDIHTAKGEWGHTNYPVVVGHEIAGVVTEVGAEVTKYKV
GDHVGVGCMVNSCRQCSSCTAGLEQYCKRGATFTYNSIDRDGSVTQGGYSQAIVVDEDFVVRIPDSLPLDKAAPLLCAGI
TLFSPLRHWNAGPGTRLAIVGLGGLGHMGVKLGAAMGAEVTVLSQSLKKMEDGLRLGAKHYHATADPDTFTKLRGSFDLM
LNTVSANLKLNDYLSLLDVDGTLVELGIPEHPMEVGAFPLALARRSLSGSNIGGIAETQEMLDFCAEHNVTPEIELIEPD
YINEAYERVLASDVRYRFVIDISKL

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=367, Percent_Identity=28.3378746594005, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI34577061, Length=328, Percent_Identity=27.4390243902439, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4501929, Length=320, Percent_Identity=27.5, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI262073058, Length=320, Percent_Identity=25.625, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI71743840, Length=320, Percent_Identity=25.625, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI71565154, Length=245, Percent_Identity=28.1632653061224, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI71565152, Length=319, Percent_Identity=25.3918495297806, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4501939, Length=354, Percent_Identity=26.271186440678, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI156523966, Length=354, Percent_Identity=26.271186440678, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786518, Length=347, Percent_Identity=51.8731988472622, Blast_Score=318, Evalue=3e-88,
Organism=Escherichia coli, GI87082401, Length=346, Percent_Identity=35.5491329479769, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI87081918, Length=315, Percent_Identity=27.6190476190476, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI226510992, Length=279, Percent_Identity=28.3154121863799, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788075, Length=281, Percent_Identity=24.1992882562278, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787863, Length=137, Percent_Identity=33.5766423357664, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788073, Length=232, Percent_Identity=28.0172413793103, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790045, Length=283, Percent_Identity=25.4416961130742, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788407, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71988145, Length=335, Percent_Identity=25.6716417910448, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17562584, Length=352, Percent_Identity=27.2727272727273, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562582, Length=351, Percent_Identity=27.3504273504274, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17562878, Length=183, Percent_Identity=30.6010928961749, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=208, Percent_Identity=29.3269230769231, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25146526, Length=213, Percent_Identity=31.4553990610329, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71997431, Length=215, Percent_Identity=31.1627906976744, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17565904, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323980, Length=345, Percent_Identity=38.8405797101449, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6319949, Length=326, Percent_Identity=38.3435582822086, Blast_Score=199, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6323961, Length=338, Percent_Identity=29.8816568047337, Blast_Score=142, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6319621, Length=329, Percent_Identity=28.2674772036474, Blast_Score=141, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6324486, Length=328, Percent_Identity=29.5731707317073, Blast_Score=135, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6323729, Length=331, Percent_Identity=28.0966767371601, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319258, Length=319, Percent_Identity=26.9592476489028, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320033, Length=325, Percent_Identity=27.6923076923077, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319257, Length=300, Percent_Identity=28, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323099, Length=282, Percent_Identity=26.5957446808511, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=274, Percent_Identity=27.007299270073, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=274, Percent_Identity=27.007299270073, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17737895, Length=364, Percent_Identity=26.6483516483516, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737897, Length=201, Percent_Identity=32.3383084577114, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17137530, Length=198, Percent_Identity=31.3131313131313, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.2 [H]

Molecular weight: Translated: 37141; Mature: 37009

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVSAYAATSATEPLTKTTIERRDPGPRDVAIDIKFAGICHSDIHTAKGEWGHTNYPVV
CCCCCHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEEEEEEECCCHHCCCCCCCCCCCCEE
VGHEIAGVVTEVGAEVTKYKVGDHVGVGCMVNSCRQCSSCTAGLEQYCKRGATFTYNSID
ECCHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
RDGSVTQGGYSQAIVVDEDFVVRIPDSLPLDKAAPLLCAGITLFSPLRHWNAGPGTRLAI
CCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
VGLGGLGHMGVKLGAAMGAEVTVLSQSLKKMEDGLRLGAKHYHATADPDTFTKLRGSFDL
EEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHCCCCEE
MLNTVSANLKLNDYLSLLDVDGTLVELGIPEHPMEVGAFPLALARRSLSGSNIGGIAETQ
EEEEEECCEEEHHCEEEEECCCEEEEECCCCCCHHHCCHHHHHHHHCCCCCCCCCHHHHH
EMLDFCAEHNVTPEIELIEPDYINEAYERVLASDVRYRFVIDISKL
HHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCEEEEEEEEECC
>Mature Secondary Structure 
STVSAYAATSATEPLTKTTIERRDPGPRDVAIDIKFAGICHSDIHTAKGEWGHTNYPVV
CCCCHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEEEEEEECCCHHCCCCCCCCCCCCEE
VGHEIAGVVTEVGAEVTKYKVGDHVGVGCMVNSCRQCSSCTAGLEQYCKRGATFTYNSID
ECCHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
RDGSVTQGGYSQAIVVDEDFVVRIPDSLPLDKAAPLLCAGITLFSPLRHWNAGPGTRLAI
CCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
VGLGGLGHMGVKLGAAMGAEVTVLSQSLKKMEDGLRLGAKHYHATADPDTFTKLRGSFDL
EEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHCCCCEE
MLNTVSANLKLNDYLSLLDVDGTLVELGIPEHPMEVGAFPLALARRSLSGSNIGGIAETQ
EEEEEECCEEEHHCEEEEECCCEEEEECCCCCCHHHCCHHHHHHHHCCCCCCCCCHHHHH
EMLDFCAEHNVTPEIELIEPDYINEAYERVLASDVRYRFVIDISKL
HHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1427101; 12788972 [H]