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The map label for this gene is idsA2_2

Identifier: 41409167

GI number: 41409167

Start: 3414585

End: 3415733

Strand: Direct

Name: idsA2_2

Synonym: MAP3069

Alternate gene names: 41409167

Gene position: 3414585-3415733 (Clockwise)

Preceding gene: 41409166

Following gene: 41409168

Centisome position: 70.7

GC content: 70.67

Gene sequence:

>1149_bases
GTGCCGTCCGGGAGGGAGCGCTGGGACACCATGGGAGCTTTGTCGTTTTCGCCCACCACCACGGCGGCGGCGCCGGCCTG
GACGCGCATCGACGACTTCGGCGGGTGGCGGGCACACGTTCGGGCGATGGTGTTGGACGAGGTCGCCGACTTCGTCGGAA
TGCGACGCGCCGACGAACTCGACCGGGCGGGGATCGGGACCGCGGGCGACATCCTGGTTCAGTTCGTCTCCGGCGGCAAG
TGCCTGCGGTCGACGTTCGTCTACCTGGGCTGGCTGTGTGGGGCACCGCGCGACCGGGCGGCGCTGCGGGCCGCCGCCAG
TTTCGAGCTGCTGCACGCCTTCGCACTGCTGCAAGACGATGTGATGGACGGTGCGCAGGAACGGCGGGGCCGTCCGGCCG
CGCATCTGCAGTTCGGCCGCTGGCATCAAGACCGCGGATTGTCCGGCTCGCCACGGCGATTCGGTGAATCGGCCGCCATC
CTGTTGGGCGATCTCTGCCTGATCTGGGCCGAACAGATGCTGCGCGACAGCGGACTCGAAGCGCGCCGCCTGCAACGCGC
GTGGCCGCGCTATGACGCCATGCGCGTCGAGCTCGCGGTGGGCCAGTTCGCCGACCTGACCAACGACATCCGGCAGTCAC
CGGGGCTGGACGCCGTGCTGGAGGTGGCGCGCCGCAAATCGGGTAACTACACGGTGCGCCGGCCGCTGGAAATCGGCGCG
ACGATGGCCGGGTGCGACGACCGGACGGTGGCCCGGCTGAGCCGCTACGGCGCGGCGGTGGGTGAAGCCTTCCAGCTGCG
CGACGACGTGCTGGGCGTCTTCGGCTCGCCGGCGGTCACCGGGAAGCCCTGCGCCGCAGATCTGTTCGAGCGCAAGGCCA
CCGCCGTGGTGGTGAGCGCCCACCAACTCGCCGATCCGCCGGTCCGGCGTGAGCTCATCGAGCTCGCCACTCGTGACGTG
CTGGACGCGGCCGCGATCGAGAGGTGGAAAGCGCTGATCGTCGAGACCGGAGCGGTGCGGCTGATCGAGCGGATGATCAG
CGACCGCGTCGCGTCGGCACGCGAGCAGCTGTGCGGCCTGCCCGTCGACGAATCGGTGCGCGCCGCGCTGGCCGAGATGG
CGGCCGTCTGTACGGATCGCGCCGAATGA

Upstream 100 bases:

>100_bases
GCGGACCGCGCCGAGCGGGCCTGACGTCAGGGCTGTGGTTTTGTCCGCGTCATCGAGGGTATGACCGGCGGTGTTCGGCC
CGGGCGGGACTGGGCAGGCC

Downstream 100 bases:

>100_bases
CCGCCACCGGCACGGGAGTTCGGTGAGCATGCGGGCCATCGAGGGCTCCGCCGATCACGTCGTGGTGATCGGGGCCGGTC
TGGCCGGCCTGTCCGCGGCG

Product: IdsA2_2

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MPSGRERWDTMGALSFSPTTTAAAPAWTRIDDFGGWRAHVRAMVLDEVADFVGMRRADELDRAGIGTAGDILVQFVSGGK
CLRSTFVYLGWLCGAPRDRAALRAAASFELLHAFALLQDDVMDGAQERRGRPAAHLQFGRWHQDRGLSGSPRRFGESAAI
LLGDLCLIWAEQMLRDSGLEARRLQRAWPRYDAMRVELAVGQFADLTNDIRQSPGLDAVLEVARRKSGNYTVRRPLEIGA
TMAGCDDRTVARLSRYGAAVGEAFQLRDDVLGVFGSPAVTGKPCAADLFERKATAVVVSAHQLADPPVRRELIELATRDV
LDAAAIERWKALIVETGAVRLIERMISDRVASAREQLCGLPVDESVRAALAEMAAVCTDRAE

Sequences:

>Translated_382_residues
MPSGRERWDTMGALSFSPTTTAAAPAWTRIDDFGGWRAHVRAMVLDEVADFVGMRRADELDRAGIGTAGDILVQFVSGGK
CLRSTFVYLGWLCGAPRDRAALRAAASFELLHAFALLQDDVMDGAQERRGRPAAHLQFGRWHQDRGLSGSPRRFGESAAI
LLGDLCLIWAEQMLRDSGLEARRLQRAWPRYDAMRVELAVGQFADLTNDIRQSPGLDAVLEVARRKSGNYTVRRPLEIGA
TMAGCDDRTVARLSRYGAAVGEAFQLRDDVLGVFGSPAVTGKPCAADLFERKATAVVVSAHQLADPPVRRELIELATRDV
LDAAAIERWKALIVETGAVRLIERMISDRVASAREQLCGLPVDESVRAALAEMAAVCTDRAE
>Mature_381_residues
PSGRERWDTMGALSFSPTTTAAAPAWTRIDDFGGWRAHVRAMVLDEVADFVGMRRADELDRAGIGTAGDILVQFVSGGKC
LRSTFVYLGWLCGAPRDRAALRAAASFELLHAFALLQDDVMDGAQERRGRPAAHLQFGRWHQDRGLSGSPRRFGESAAIL
LGDLCLIWAEQMLRDSGLEARRLQRAWPRYDAMRVELAVGQFADLTNDIRQSPGLDAVLEVARRKSGNYTVRRPLEIGAT
MAGCDDRTVARLSRYGAAVGEAFQLRDDVLGVFGSPAVTGKPCAADLFERKATAVVVSAHQLADPPVRRELIELATRDVL
DAAAIERWKALIVETGAVRLIERMISDRVASAREQLCGLPVDESVRAALAEMAAVCTDRAE

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=280, Percent_Identity=31.0714285714286, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508563, Length=214, Percent_Identity=27.5700934579439, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 41732; Mature: 41601

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSGRERWDTMGALSFSPTTTAAAPAWTRIDDFGGWRAHVRAMVLDEVADFVGMRRADEL
CCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DRAGIGTAGDILVQFVSGGKCLRSTFVYLGWLCGAPRDRAALRAAASFELLHAFALLQDD
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VMDGAQERRGRPAAHLQFGRWHQDRGLSGSPRRFGESAAILLGDLCLIWAEQMLRDSGLE
HHCCHHHHCCCCCHHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
ARRLQRAWPRYDAMRVELAVGQFADLTNDIRQSPGLDAVLEVARRKSGNYTVRRPLEIGA
HHHHHHHCCCHHHHEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECHHHHCC
TMAGCDDRTVARLSRYGAAVGEAFQLRDDVLGVFGSPAVTGKPCAADLFERKATAVVVSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEEEH
HQLADPPVRRELIELATRDVLDAAAIERWKALIVETGAVRLIERMISDRVASAREQLCGL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVDESVRAALAEMAAVCTDRAE
CCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PSGRERWDTMGALSFSPTTTAAAPAWTRIDDFGGWRAHVRAMVLDEVADFVGMRRADEL
CCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DRAGIGTAGDILVQFVSGGKCLRSTFVYLGWLCGAPRDRAALRAAASFELLHAFALLQDD
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VMDGAQERRGRPAAHLQFGRWHQDRGLSGSPRRFGESAAILLGDLCLIWAEQMLRDSGLE
HHCCHHHHCCCCCHHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
ARRLQRAWPRYDAMRVELAVGQFADLTNDIRQSPGLDAVLEVARRKSGNYTVRRPLEIGA
HHHHHHHCCCHHHHEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECHHHHCC
TMAGCDDRTVARLSRYGAAVGEAFQLRDDVLGVFGSPAVTGKPCAADLFERKATAVVVSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEEEH
HQLADPPVRRELIELATRDVLDAAAIERWKALIVETGAVRLIERMISDRVASAREQLCGL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVDESVRAALAEMAAVCTDRAE
CCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]