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The map label for this gene is ung

Identifier: 41409114

GI number: 41409114

Start: 3355645

End: 3356328

Strand: Reverse

Name: ung

Synonym: MAP3016c

Alternate gene names: 41409114

Gene position: 3356328-3355645 (Counterclockwise)

Preceding gene: 41409115

Following gene: 41409111

Centisome position: 69.49

GC content: 71.2

Gene sequence:

>684_bases
ATGACGGCGCGCCCGCTGAATGAACTCGTCGAGCCCGGCTGGGCGCGTGCGTTGCAGCCGGTGGCCGAGCAGGTCGCCCG
GATGGGGCAGTTTCTGCGGGCCGAGATCGCGGCCGGGCGCCGGTACCTGCCGGCCGGCCCAAACGTGTTGCGCGCGTTCA
CCTATCCCTTCGACGAGGTCAAGGTGCTCATCGTTGGGCAGGATCCCTATCCGACGCCGGGACACGCTGTGGGGCTGAGC
TTTTCGGTGGCACCCGACGTGTCGCCGCTGCCGCGCAGCCTGGCCAACATCTTCCAGGAGTACACCGCGGACCTGGGCCA
CCCGCCGCCCTCGTGCGGCGACCTGACGCCCTGGGCGCAGCGCGGCGTGCTGCTGCTGAACAGGGTGCTCACCGTGCGCC
CCAGCAACCCGGCGTCGCACCGGGGCAAGGGCTGGGAGCCGGTGACCGAGTGCGCCATCCGGGCGCTGACCGCGCGCCAG
CAGCCCCTGGTCGCCATCCTGTGGGGCCGTGACGCCTCGACCCTGAAACCGATTCTGGCCCAAGGTAATTGCGTGGCCAT
CGAGTCGCCGCACCCGTCTCCGCTGTCGGCGTCGCGGGGGTTCTTCGGGTCGCGGCCGTTCAGCCGGGCCAACAAGCTGC
TGGCCGAGATGGGCGCCGACGAGATCGACTGGCGGCTGCCCTGA

Upstream 100 bases:

>100_bases
GTCGACGAGCGGGAGTGGAGCGGCCCCGCCGGCTGGCAGTCGTACTAGGGTGGCCCGGTGATCTCTAAGTGACCGATCCC
GCGGCCGGCGGGGGCCGGCG

Downstream 100 bases:

>100_bases
CGCTCGCGGTTGGGCCGGCGCCCGTCACGCTGGCGTGACGCTCGGCGCCGGCCGTCACGCTGGCGTGACGCTCGGCCGTG
GCCGTCACGCTGGCGTGACG

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTARPLNELVEPGWARALQPVAEQVARMGQFLRAEIAAGRRYLPAGPNVLRAFTYPFDEVKVLIVGQDPYPTPGHAVGLS
FSVAPDVSPLPRSLANIFQEYTADLGHPPPSCGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEPVTECAIRALTARQ
QPLVAILWGRDASTLKPILAQGNCVAIESPHPSPLSASRGFFGSRPFSRANKLLAEMGADEIDWRLP

Sequences:

>Translated_227_residues
MTARPLNELVEPGWARALQPVAEQVARMGQFLRAEIAAGRRYLPAGPNVLRAFTYPFDEVKVLIVGQDPYPTPGHAVGLS
FSVAPDVSPLPRSLANIFQEYTADLGHPPPSCGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEPVTECAIRALTARQ
QPLVAILWGRDASTLKPILAQGNCVAIESPHPSPLSASRGFFGSRPFSRANKLLAEMGADEIDWRLP
>Mature_226_residues
TARPLNELVEPGWARALQPVAEQVARMGQFLRAEIAAGRRYLPAGPNVLRAFTYPFDEVKVLIVGQDPYPTPGHAVGLSF
SVAPDVSPLPRSLANIFQEYTADLGHPPPSCGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEPVTECAIRALTARQQ
PLVAILWGRDASTLKPILAQGNCVAIESPHPSPLSASRGFFGSRPFSRANKLLAEMGADEIDWRLP

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI6224979, Length=199, Percent_Identity=41.2060301507538, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI19718751, Length=199, Percent_Identity=41.2060301507538, Blast_Score=143, Evalue=1e-34,
Organism=Escherichia coli, GI1788934, Length=197, Percent_Identity=41.1167512690355, Blast_Score=143, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17556304, Length=221, Percent_Identity=36.1990950226244, Blast_Score=147, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6323620, Length=238, Percent_Identity=37.3949579831933, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24668; Mature: 24536

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARPLNELVEPGWARALQPVAEQVARMGQFLRAEIAAGRRYLPAGPNVLRAFTYPFDEV
CCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCE
KVLIVGQDPYPTPGHAVGLSFSVAPDVSPLPRSLANIFQEYTADLGHPPPSCGDLTPWAQ
EEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
RGVLLLNRVLTVRPSNPASHRGKGWEPVTECAIRALTARQQPLVAILWGRDASTLKPILA
HHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
QGNCVAIESPHPSPLSASRGFFGSRPFSRANKLLAEMGADEIDWRLP
CCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TARPLNELVEPGWARALQPVAEQVARMGQFLRAEIAAGRRYLPAGPNVLRAFTYPFDEV
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCE
KVLIVGQDPYPTPGHAVGLSFSVAPDVSPLPRSLANIFQEYTADLGHPPPSCGDLTPWAQ
EEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
RGVLLLNRVLTVRPSNPASHRGKGWEPVTECAIRALTARQQPLVAILWGRDASTLKPILA
HHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
QGNCVAIESPHPSPLSASRGFFGSRPFSRANKLLAEMGADEIDWRLP
CCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA