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The map label for this gene is amiC

Identifier: 41409052

GI number: 41409052

Start: 3287253

End: 3288668

Strand: Reverse

Name: amiC

Synonym: MAP2954c

Alternate gene names: 41409052

Gene position: 3288668-3287253 (Counterclockwise)

Preceding gene: 41409053

Following gene: 41409050

Centisome position: 68.09

GC content: 72.18

Gene sequence:

>1416_bases
ATGCGACACGTGCACGCGTTCGGCGACGACGCCCTCGGCGACCTCGACGCGGTCGGGCTGGCCGACGCCCTCCGAGCCGG
TCGGGTGAGCCGGGCGGAGGTGGTCGAGGCCGCGATCGCGCGCACCGAGGCCGTCGACCCGCTGCTCAATGGCTTGGCGT
ACGCGGCTTTTCAGCAGGCGCGGTCGGCCGCCGAGCGGCCCGACCCGCCCGCCGGTTTCTCCGCGTTTTTCGACGGCGTC
CCGACGTTCATCAAGGATAACATCGACGTCGCCGGCCAGCCCACCATGCACGGCACCGACGCGTGGACGTCGTACAACGC
CGTCGCAGACAGCGTGTTCACCCGGCTGTACCTGGCCACCGGGCTGATCTCGGTGGGCAAGACGCAGCTGTCGGAGTTCG
GTTTCAGCGCGGCGGCCGAGCATCCCCGGCTGGGCCCGGTCCGCAACCCGTGGGACACCGACTACACCGCCGGGGCGTCG
TCGTCGGGATCGGGCGCGTTCGTCGGCGCCGGCGTGGTGCCGATCGCGCACGCCAACGACGGCGGCGGCTCCATCCGCAT
CCCGGCGGCCTGCAACGGGCTGGTCGGTCTTAAGCCGTCGCGCGGGCGGCTGCCGCTGGATGCCACGCTGCGCCGGATGC
CGGTCGGGGTGGTGGCCAACGGGGTGGTGACGCGTTCGGTGCGCGACACCGCGGCGTTCTACCGGGAGGCCGAGCGGATC
TGGCGCAACAGGCTGGCGCCGATCGGCGACGTCACCGGCCCGGGCCGCCAGCGGCTGCGGATCGCGGTGCTGACCCGGTC
GATCCAGCGCGAGTGCAGTCCGCGGATCCGGGAGCTGACGCTCAAGACGGCCGGCCTGCTCGAGGAGCTCGGCCACCGGG
TCGATCTCCTCGACGAGCCCCCGGTCGCGGCCAGCTTCGTCGACGATTTCGTGCTGTATTGGGGGTTTTTGGCGCTGGCC
CCGGTGCGCAGCGGCCGGCACCTGTTCGGCCCGACGTTCGACCGCGACAAGCTGGACAGCCTGACCCGGGGCCTGTACCG
GCACACCAGCCGCAACCTGCACCGCCTGCCGCTGGCGATCGCGCGGCTGCGCCGGGCGCGACGGCGCACCGCGCCCCTGT
TCGGCATCTACGACGCGGCGCTGACCCCGACCGTCGCCGACGAGACGCCGCGCATCGGTTTCCTGGCGCCGACCGACTAT
CAGCAGGTGATCAGCCGGTTGATCGACTGGGTGTCGTTCACCCCGCTGCACAACGTCACCGGCGAGCCGGCCATCTCGCT
GCCGTTGGCGCAGTCCGAGCACGGCATGCCGGTCGGCATGATGCTGTCGGCCGACATTGGCCAGGAGGCGTTGCTGCTGC
AGCTGGCCTACGAGCTGGAAGAGGCGCGGCCGTGGGCGCGCATCCAGGCCGCCTGA

Upstream 100 bases:

>100_bases
TCACCCGGTTCGTGCGCTTCGAGGTCGGCCAGGCCTGACCGGTCGCGCGCAGCGGCACAAAACCTGCCGACGGCGTGCCC
GCGCGGGTTAGCGTCGGTGC

Downstream 100 bases:

>100_bases
TCAGCCGTCGGAGCCCAGTTTCTGCAGCATTCGTTTGAACTCGCGCTGCTGAGTCTCGGTGAGCTTGGCCAGGATTCGGG
CATCGGCGCCGCGCACGGCG

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MRHVHAFGDDALGDLDAVGLADALRAGRVSRAEVVEAAIARTEAVDPLLNGLAYAAFQQARSAAERPDPPAGFSAFFDGV
PTFIKDNIDVAGQPTMHGTDAWTSYNAVADSVFTRLYLATGLISVGKTQLSEFGFSAAAEHPRLGPVRNPWDTDYTAGAS
SSGSGAFVGAGVVPIAHANDGGGSIRIPAACNGLVGLKPSRGRLPLDATLRRMPVGVVANGVVTRSVRDTAAFYREAERI
WRNRLAPIGDVTGPGRQRLRIAVLTRSIQRECSPRIRELTLKTAGLLEELGHRVDLLDEPPVAASFVDDFVLYWGFLALA
PVRSGRHLFGPTFDRDKLDSLTRGLYRHTSRNLHRLPLAIARLRRARRRTAPLFGIYDAALTPTVADETPRIGFLAPTDY
QQVISRLIDWVSFTPLHNVTGEPAISLPLAQSEHGMPVGMMLSADIGQEALLLQLAYELEEARPWARIQAA

Sequences:

>Translated_471_residues
MRHVHAFGDDALGDLDAVGLADALRAGRVSRAEVVEAAIARTEAVDPLLNGLAYAAFQQARSAAERPDPPAGFSAFFDGV
PTFIKDNIDVAGQPTMHGTDAWTSYNAVADSVFTRLYLATGLISVGKTQLSEFGFSAAAEHPRLGPVRNPWDTDYTAGAS
SSGSGAFVGAGVVPIAHANDGGGSIRIPAACNGLVGLKPSRGRLPLDATLRRMPVGVVANGVVTRSVRDTAAFYREAERI
WRNRLAPIGDVTGPGRQRLRIAVLTRSIQRECSPRIRELTLKTAGLLEELGHRVDLLDEPPVAASFVDDFVLYWGFLALA
PVRSGRHLFGPTFDRDKLDSLTRGLYRHTSRNLHRLPLAIARLRRARRRTAPLFGIYDAALTPTVADETPRIGFLAPTDY
QQVISRLIDWVSFTPLHNVTGEPAISLPLAQSEHGMPVGMMLSADIGQEALLLQLAYELEEARPWARIQAA
>Mature_471_residues
MRHVHAFGDDALGDLDAVGLADALRAGRVSRAEVVEAAIARTEAVDPLLNGLAYAAFQQARSAAERPDPPAGFSAFFDGV
PTFIKDNIDVAGQPTMHGTDAWTSYNAVADSVFTRLYLATGLISVGKTQLSEFGFSAAAEHPRLGPVRNPWDTDYTAGAS
SSGSGAFVGAGVVPIAHANDGGGSIRIPAACNGLVGLKPSRGRLPLDATLRRMPVGVVANGVVTRSVRDTAAFYREAERI
WRNRLAPIGDVTGPGRQRLRIAVLTRSIQRECSPRIRELTLKTAGLLEELGHRVDLLDEPPVAASFVDDFVLYWGFLALA
PVRSGRHLFGPTFDRDKLDSLTRGLYRHTSRNLHRLPLAIARLRRARRRTAPLFGIYDAALTPTVADETPRIGFLAPTDY
QQVISRLIDWVSFTPLHNVTGEPAISLPLAQSEHGMPVGMMLSADIGQEALLLQLAYELEEARPWARIQAA

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=510, Percent_Identity=25.6862745098039, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI195972892, Length=258, Percent_Identity=30.6201550387597, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17538252, Length=302, Percent_Identity=26.8211920529801, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17556264, Length=298, Percent_Identity=26.510067114094, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17537465, Length=211, Percent_Identity=29.3838862559242, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319685, Length=124, Percent_Identity=40.3225806451613, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323950, Length=124, Percent_Identity=37.0967741935484, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356731, Length=277, Percent_Identity=27.7978339350181, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24652985, Length=202, Percent_Identity=30.6930693069307, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922090, Length=202, Percent_Identity=30.6930693069307, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24652981, Length=202, Percent_Identity=30.6930693069307, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24652983, Length=202, Percent_Identity=30.6930693069307, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550774, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648435, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648437, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644968, Length=231, Percent_Identity=29.004329004329, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648113, Length=485, Percent_Identity=26.5979381443299, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 50902; Mature: 50902

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHVHAFGDDALGDLDAVGLADALRAGRVSRAEVVEAAIARTEAVDPLLNGLAYAAFQQA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSAAERPDPPAGFSAFFDGVPTFIKDNIDVAGQPTMHGTDAWTSYNAVADSVFTRLYLAT
HHHHCCCCCCCCHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GLISVGKTQLSEFGFSAAAEHPRLGPVRNPWDTDYTAGASSSGSGAFVGAGVVPIAHAND
HHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCC
GGGSIRIPAACNGLVGLKPSRGRLPLDATLRRMPVGVVANGVVTRSVRDTAAFYREAERI
CCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHH
WRNRLAPIGDVTGPGRQRLRIAVLTRSIQRECSPRIRELTLKTAGLLEELGHRVDLLDEP
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVAASFVDDFVLYWGFLALAPVRSGRHLFGPTFDRDKLDSLTRGLYRHTSRNLHRLPLAI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
ARLRRARRRTAPLFGIYDAALTPTVADETPRIGFLAPTDYQQVISRLIDWVSFTPLHNVT
HHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCC
GEPAISLPLAQSEHGMPVGMMLSADIGQEALLLQLAYELEEARPWARIQAA
CCCCEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEECCC
>Mature Secondary Structure
MRHVHAFGDDALGDLDAVGLADALRAGRVSRAEVVEAAIARTEAVDPLLNGLAYAAFQQA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSAAERPDPPAGFSAFFDGVPTFIKDNIDVAGQPTMHGTDAWTSYNAVADSVFTRLYLAT
HHHHCCCCCCCCHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GLISVGKTQLSEFGFSAAAEHPRLGPVRNPWDTDYTAGASSSGSGAFVGAGVVPIAHAND
HHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCC
GGGSIRIPAACNGLVGLKPSRGRLPLDATLRRMPVGVVANGVVTRSVRDTAAFYREAERI
CCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHH
WRNRLAPIGDVTGPGRQRLRIAVLTRSIQRECSPRIRELTLKTAGLLEELGHRVDLLDEP
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVAASFVDDFVLYWGFLALAPVRSGRHLFGPTFDRDKLDSLTRGLYRHTSRNLHRLPLAI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
ARLRRARRRTAPLFGIYDAALTPTVADETPRIGFLAPTDYQQVISRLIDWVSFTPLHNVT
HHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCC
GEPAISLPLAQSEHGMPVGMMLSADIGQEALLLQLAYELEEARPWARIQAA
CCCCEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]