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The map label for this gene is nicT

Identifier: 41409022

GI number: 41409022

Start: 3257877

End: 3259109

Strand: Direct

Name: nicT

Synonym: MAP2924

Alternate gene names: 41409022

Gene position: 3257877-3259109 (Clockwise)

Preceding gene: 41409021

Following gene: 41409023

Centisome position: 67.45

GC content: 68.45

Gene sequence:

>1233_bases
GTGCCCGCCTTGCGTCCGGCAAGACGCGGAACTTACAGTCGTGCCCGTTGCCCTGTGCCCGACACCGCCCGCGCCGGAAG
GACCCCCGTGACCAGTACGGAGATCGACCGGTGGCCGGCACGGGCGACCAGGTTTCTCGGCGCGCTGGCGCCGACGGAAT
GGTGGCGGCTGGCGTCGATGCTGGGCGCCATCCTCGCGCTGCACCTGATCGGCTGGTTGACCTTGGTGCTGTTGGTGGCC
CCGGGGCAATACAGCTTGGGCGGCAAGGCATTTGGCGTCGGTGTCGGATTGACGGCCTACACCCTGGGTCTGCGGCACGC
CTTCGACGCCGACCACATCGCCGCGATCGACAACACCACCCGCAAGCTGATGAACGACGGGCAGCGCCCGCTGGCCGTCG
GCTTCTTCTTCTCGCTGGGCCATTCCACGGTGGTGTTCGCGCTGGCGGTGCTGCTGGCCTGCGGGGTGAGGACGGTGGTG
GGGCCGGTGCGCGACGACTCGTCGGCGCTGCACCACTACACCGGGCTGATCGGCACCAGCGTCTCGGGCGTGTTCCTCTA
TGCGATCGCCCTGCTCAACGTCGTCGTCCTGGTCGGCATCCTGCGCGTCCTCGCGCGAGTGCGCCGGGGTGACTACGACC
CGCACACCGACGCCGCGGAATTGGAGCGGCAGCTGGACAACCGGGGGCTGATGAACCGGTGGCTGGGCCGGTTCACCAAG
TCGATCACCCAGTCCTGGCACTGCTATCCGGTCGGCCTGCTGTTCGGGCTCGGTTTCGACACCGCCACCGAGGTCGCGCT
GCTGGTGCTGGCCGGCACCAGCGCGGCGGCCGGGCTGCCCTGGTACGCCATCCTGTGCCTGCCGGTGCTGTTCGCGGCCG
GCATGTGCCTGCTGGACACCATCGACGGCTCGTTCATGAACTTCGCCTACGGCTGGGCGTTTTCCAACCCGGTGCGCAAG
ATCTACTACAACATCATCATCACCGCGCTGTCGGTGGCGGTCGCGTGGGTGATCGGCAGCATCGAGCTGCTCGTCCTGTT
CGCCGACGAATTCGGTTGGCGGGGCTCGTTCTGGGACTGGCTCGGCGGGCTGGACCTGAACACGGTCGGTTACGCCGTCG
TCGGCATGTTCGTCCTCACCTGGGCGGTGGCCCTGCTGATCTGGCGGTACGGACGCATCGAAGAGAGGTGGGCCGGCGCC
GATCCGCGCGCCGGGACCGGCCGAGAAGCCTGA

Upstream 100 bases:

>100_bases
GCGCAGATGGCCCGCGGCCAGTACTGGATTCACCCGGCGCTGCCCGAGGTCGTCGAGAACGCGCTGCTGGGCCTGTACTG
ATTTCGCGGGCACGGGCCGT

Downstream 100 bases:

>100_bases
ACCGCGCCCTGACGGTCGGGCCGCCCCGGGCCCGACCGCCGACTGGCGCGCGTGTGGGCCGGACGCCAGACTGGCCGGGT
GCCCGGTTCGCTGCGCGACG

Product: NicT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MPALRPARRGTYSRARCPVPDTARAGRTPVTSTEIDRWPARATRFLGALAPTEWWRLASMLGAILALHLIGWLTLVLLVA
PGQYSLGGKAFGVGVGLTAYTLGLRHAFDADHIAAIDNTTRKLMNDGQRPLAVGFFFSLGHSTVVFALAVLLACGVRTVV
GPVRDDSSALHHYTGLIGTSVSGVFLYAIALLNVVVLVGILRVLARVRRGDYDPHTDAAELERQLDNRGLMNRWLGRFTK
SITQSWHCYPVGLLFGLGFDTATEVALLVLAGTSAAAGLPWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSNPVRK
IYYNIIITALSVAVAWVIGSIELLVLFADEFGWRGSFWDWLGGLDLNTVGYAVVGMFVLTWAVALLIWRYGRIEERWAGA
DPRAGTGREA

Sequences:

>Translated_410_residues
MPALRPARRGTYSRARCPVPDTARAGRTPVTSTEIDRWPARATRFLGALAPTEWWRLASMLGAILALHLIGWLTLVLLVA
PGQYSLGGKAFGVGVGLTAYTLGLRHAFDADHIAAIDNTTRKLMNDGQRPLAVGFFFSLGHSTVVFALAVLLACGVRTVV
GPVRDDSSALHHYTGLIGTSVSGVFLYAIALLNVVVLVGILRVLARVRRGDYDPHTDAAELERQLDNRGLMNRWLGRFTK
SITQSWHCYPVGLLFGLGFDTATEVALLVLAGTSAAAGLPWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSNPVRK
IYYNIIITALSVAVAWVIGSIELLVLFADEFGWRGSFWDWLGGLDLNTVGYAVVGMFVLTWAVALLIWRYGRIEERWAGA
DPRAGTGREA
>Mature_409_residues
PALRPARRGTYSRARCPVPDTARAGRTPVTSTEIDRWPARATRFLGALAPTEWWRLASMLGAILALHLIGWLTLVLLVAP
GQYSLGGKAFGVGVGLTAYTLGLRHAFDADHIAAIDNTTRKLMNDGQRPLAVGFFFSLGHSTVVFALAVLLACGVRTVVG
PVRDDSSALHHYTGLIGTSVSGVFLYAIALLNVVVLVGILRVLARVRRGDYDPHTDAAELERQLDNRGLMNRWLGRFTKS
ITQSWHCYPVGLLFGLGFDTATEVALLVLAGTSAAAGLPWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSNPVRKI
YYNIIITALSVAVAWVIGSIELLVLFADEFGWRGSFWDWLGGLDLNTVGYAVVGMFVLTWAVALLIWRYGRIEERWAGAD
PRAGTGREA

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 44617; Mature: 44486

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALRPARRGTYSRARCPVPDTARAGRTPVTSTEIDRWPARATRFLGALAPTEWWRLASM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
LGAILALHLIGWLTLVLLVAPGQYSLGGKAFGVGVGLTAYTLGLRHAFDADHIAAIDNTT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RKLMNDGQRPLAVGFFFSLGHSTVVFALAVLLACGVRTVVGPVRDDSSALHHYTGLIGTS
HHHHCCCCCCEEHHHHHHHCHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHH
VSGVFLYAIALLNVVVLVGILRVLARVRRGDYDPHTDAAELERQLDNRGLMNRWLGRFTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
SITQSWHCYPVGLLFGLGFDTATEVALLVLAGTSAAAGLPWYAILCLPVLFAAGMCLLDT
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHEECCCHHCCCHHHHHHHHHHHHHCCHHHHHH
IDGSFMNFAYGWAFSNPVRKIYYNIIITALSVAVAWVIGSIELLVLFADEFGWRGSFWDW
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCHHHH
LGGLDLNTVGYAVVGMFVLTWAVALLIWRYGRIEERWAGADPRAGTGREA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PALRPARRGTYSRARCPVPDTARAGRTPVTSTEIDRWPARATRFLGALAPTEWWRLASM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
LGAILALHLIGWLTLVLLVAPGQYSLGGKAFGVGVGLTAYTLGLRHAFDADHIAAIDNTT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RKLMNDGQRPLAVGFFFSLGHSTVVFALAVLLACGVRTVVGPVRDDSSALHHYTGLIGTS
HHHHCCCCCCEEHHHHHHHCHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHH
VSGVFLYAIALLNVVVLVGILRVLARVRRGDYDPHTDAAELERQLDNRGLMNRWLGRFTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
SITQSWHCYPVGLLFGLGFDTATEVALLVLAGTSAAAGLPWYAILCLPVLFAAGMCLLDT
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHEECCCHHCCCHHHHHHHHHHHHHCCHHHHHH
IDGSFMNFAYGWAFSNPVRKIYYNIIITALSVAVAWVIGSIELLVLFADEFGWRGSFWDW
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCHHHH
LGGLDLNTVGYAVVGMFVLTWAVALLIWRYGRIEERWAGADPRAGTGREA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]