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The map label for this gene is dapB

Identifier: 41408976

GI number: 41408976

Start: 3206935

End: 3207672

Strand: Reverse

Name: dapB

Synonym: MAP2878c

Alternate gene names: 41408976

Gene position: 3207672-3206935 (Counterclockwise)

Preceding gene: 41408977

Following gene: 41408975

Centisome position: 66.41

GC content: 70.05

Gene sequence:

>738_bases
ATGCGGGTAGGAGTGCTGGGAGCCAAGGGAAAAGTCGGGTCGACGATGGTGGCGGCGGTGCAGGCCGCCGAGGACCTGAC
GCTGTCCGCCGAGGTGGACGCCGGCGATCCGCTGAGTCTGCTGACCGACGGCGGCACCGAGGCGGTGATCGACTTCACCC
ATCCCGACGTCGTGATGGGCAACCTGGAGTTCTTGGTGCGCAACGGAATTCACGCCGTCGTCGGCACCACCGGCTTCACC
GCCGAACGGCTGGCGCAGGTCCGGGAGTGGCTGGCCGACAGCCCCGGCACGTCGGTGCTCGTCGCGCCGAACTTCGCCAT
CGGGGCCGTGCTGTCGATGCACTTCGCCAAGCAGGCGGCGCGCTTCTTCGACTCGGCGGAGGTGATCGAACTGCATCATC
CGCACAAGGCCGACGCCCCGTCGGGCACCGCGACCCGCACCGCCAAACTGATCGCCGAAGCGCGAAAAGGCTTGCCCCCC
AACCCCGATGCCACCAGCACCAGCCTGCCGGGAGCGCGCGGCGCCGACGTGGACGGCATCCCCGTGCACGCGGTGCGGCT
GGCCGGGCTGGTCGCCCATCAGGAGATCCTGTTCGGCACCGAGGGCGAGACGCTGAGCATCCGCCACGACAGCCTGGACC
GGACCTCGTTCGTGCCCGGTGTGCTGCTGGCGGTGCGGCGCATCAGGGAACACCCGGGCCTGACCGTGGGCCTCGAACCG
CTGCTCGACCTGGGCTGA

Upstream 100 bases:

>100_bases
CCCGAGCAACCCGCTCCGTACACCGAAGCGGGCTGGATCGTGCACACCTGAACCCGCGGCACCGCGCGGCGCGGAATGTG
ACCCGGTCTAGGCTTCAGCC

Downstream 100 bases:

>100_bases
GCAAACCGGCTATGAGCAAACGGCTATGAACAAAGCGCTGCGCATCCAACTGCTCGTCGCCTTCCTGTGTGTGGCGCTGG
TGGTGTACTTCGCGCTGCTC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MRVGVLGAKGKVGSTMVAAVQAAEDLTLSAEVDAGDPLSLLTDGGTEAVIDFTHPDVVMGNLEFLVRNGIHAVVGTTGFT
AERLAQVREWLADSPGTSVLVAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKADAPSGTATRTAKLIAEARKGLPP
NPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEILFGTEGETLSIRHDSLDRTSFVPGVLLAVRRIREHPGLTVGLEP
LLDLG

Sequences:

>Translated_245_residues
MRVGVLGAKGKVGSTMVAAVQAAEDLTLSAEVDAGDPLSLLTDGGTEAVIDFTHPDVVMGNLEFLVRNGIHAVVGTTGFT
AERLAQVREWLADSPGTSVLVAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKADAPSGTATRTAKLIAEARKGLPP
NPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEILFGTEGETLSIRHDSLDRTSFVPGVLLAVRRIREHPGLTVGLEP
LLDLG
>Mature_245_residues
MRVGVLGAKGKVGSTMVAAVQAAEDLTLSAEVDAGDPLSLLTDGGTEAVIDFTHPDVVMGNLEFLVRNGIHAVVGTTGFT
AERLAQVREWLADSPGTSVLVAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKADAPSGTATRTAKLIAEARKGLPP
NPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEILFGTEGETLSIRHDSLDRTSFVPGVLLAVRRIREHPGLTVGLEP
LLDLG

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=270, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_MYCPA (Q73VY3)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_961812.1
- ProteinModelPortal:   Q73VY3
- SMR:   Q73VY3
- EnsemblBacteria:   EBMYCT00000040157
- GeneID:   2720864
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP2878c
- NMPDR:   fig|262316.1.peg.2878
- GeneTree:   EBGT00050000017074
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 25561; Mature: 25561

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGVLGAKGKVGSTMVAAVQAAEDLTLSAEVDAGDPLSLLTDGGTEAVIDFTHPDVVMG
CEEEEECCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCEEEECCCCEEEEEECCCCEEEH
NLEFLVRNGIHAVVGTTGFTAERLAQVREWLADSPGTSVLVAPNFAIGAVLSMHFAKQAA
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHH
RFFDSAEVIELHHPHKADAPSGTATRTAKLIAEARKGLPPNPDATSTSLPGARGADVDGI
HHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PVHAVRLAGLVAHQEILFGTEGETLSIRHDSLDRTSFVPGVLLAVRRIREHPGLTVGLEP
CHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECHH
LLDLG
HHCCC
>Mature Secondary Structure
MRVGVLGAKGKVGSTMVAAVQAAEDLTLSAEVDAGDPLSLLTDGGTEAVIDFTHPDVVMG
CEEEEECCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCEEEECCCCEEEEEECCCCEEEH
NLEFLVRNGIHAVVGTTGFTAERLAQVREWLADSPGTSVLVAPNFAIGAVLSMHFAKQAA
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHH
RFFDSAEVIELHHPHKADAPSGTATRTAKLIAEARKGLPPNPDATSTSLPGARGADVDGI
HHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PVHAVRLAGLVAHQEILFGTEGETLSIRHDSLDRTSFVPGVLLAVRRIREHPGLTVGLEP
CHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECHH
LLDLG
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA